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  3. Pemetrex 100mg Injection

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Quick summary
Quick Summary

Pemetrex 100mg Injection

Prescription Required
Cold Chain Required
pemetrexed
Written By:Aswini Priya VelmuruganPG in Biotechnology Reviewed By:Dr. Tejashwin AdigaMBBS

Last updated on 29 Apr 2026 | 05:02 AM (IST)

₹686

MRP: ₹857.3

(You Save ₹171.3)

1 VIAL(s)

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Pemetrex 100mg Injection
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Pemetrex 100mg Injection


Prescription Required
Required
Cold Chain Required
Cold Chain
Info

Salt Composition

PEMETREXED

Marketer

BDR PHARMACEUTICALS INTERNATIONALS PVT LTD


Prepaid Only. Non-Returnable.

Info

20% OFF

Pemetrex 100mg Injection
Preview
We are Rated 4.8 ⭐️ On Google

₹686

MRP: ₹857.30

Inclusive of all taxes

20% Off

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1 Vial(s)

1 Vial(s)

₹ 686.0/Unit

1 VIAL(s)


Prescription Required
Prescription Required
Cold Chain Required
Cold Chain
Info

Salt Composition

PEMETREXED

Marketer

BDR PHARMACEUTICALS INTERNATIONALS PVT LTD


Prepaid Only. Non-Returnable.

Info
Dispatch Date Icon

Dispatch: Today

Care delivered without the wait. Your order is prioritized for rapid dispatch to ensure it reaches your doorstep on time.

Substitutes

Pemsted 100mg Injection

HALSTED PHARMA ...

₹ 536.00/injection

21% cheaper

Pemeplast 100mg Injection

NEON LABORATORI...

₹ 584.00/injection

14% cheaper

Giopem 100mg Injection

GLS PHARMA LTD

₹ 616.00/injection

10% cheaper

Pemnat 100mg Injection

NATCO PHARMA LT...

₹ 643.00/injection

6% cheaper

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Introduction

Pemetrex 100 mg/vial (injection) is an anticancer medicine containing the active ingredient Pemetrexed.  It belongs to the medication class known as an antifolate agent. Pemetrex injection uses in the treat non-small cell lung cancer and malignant pleural mesothelioma (cancers of the lungs and chest). This Injection is given alone or in combination with another anticancer medicine, such as cisplatin. Your doctor may prescribe corticosteroids, folic acid, and vitamin B12 to limit the side effects.  

Blood tests will be taken before each infusion to determine whether your kidney and liver functions are adequate and whether you have enough blood cells to receive this medicine. Before starting treatment with Pemetrex 100mg Injection, it is very important to tell your physician if you are currently or previously had any medical conditions  of  kidney problems, heart disorders, fluid accumulation in the lungs, Report your doctor if you recently had or currently having radiotherapy or any vaccination before taking this medication. 

Inform your doctor immediately if you are planning to get pregnant or think you may be pregnant. Use effective birth control during the treatment and at least six months after the last dose of Pemetrex 100mg Injection. In men, it is recommended not to father a child during and up to 3 months after the treatment. So it is advised to get suggestions about fertility concerns from your doctor. This medication is not recommended for adolescents and children under 18 years of age. 

Uses

Pemetrex 100mg uses are

  • Malignant pleural mesothelioma

  • Non-small cell lung carcinoma

How Pemetrex 100mg Injection works

Pemetrex 100mg inhibits the mechanism required for cell division and replication by blocking specific enzymes involved in folate metabolism (essential for cell replication) and DNA synthesis, which will prevent the cancer cells from growing and multiplying.

Interaction of Pemetrex 100mg Injection with other drugs

Inform your healthcare provider about all your medicines, including prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products. Certain medications such as  may interact with Pemetrex 100mg and reduce effectiveness by causing undesirable side effects.

Storage conditions

  • Keep the tablets away from light and moisture.

  • Store refrigerated at 2°C to 8°C.

  • Keep the tablets out of the reach of children and animals.

How to use Pemetrex 100mg Injection

Pemetrex 100mg injection is administered as an intravenous infusion into the vein. If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administer. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.

Safety Advice for Pemetrex 100mg Injection

Breast Feeding-unsafe

Breast Feeding

Unsafe

It is unsafe to breastfeed while taking Pemetrex 100mg because it can cause toxicity to the baby. If you are breastfeeding a baby, it has to be discontinued. Please consult your physician for more advice.

Alcohol-Consult your doctor

Alcohol

Consult Your Doctor

It is unknown whether consuming alcohol while taking a Pemetrex 100mg injection is safe. Please speak with your physician.

Liver-Consult your doctor

Liver

Consult Your Doctor

Inform your physician about any underlying liver disorders before taking Pemetrex 100mg, as this medication should be used with caution in liver disease patients.

Lungs-Consult your doctor

Lungs

Consult Your Doctor

Consult your doctor if you experience any symptoms like; shortness of breath, blockage, or inflammation in the lining of the lung while taking  Pemetrex 100mg injection

Driving-unsafe

Driving

Unsafe

While taking Pemetrex 100mg injection, it is unsafe to drive or use machines because it may cause nausea, fatigue, vomiting, etc. Talk to your doctor for more information.

Pregnancy-unsafe

Pregnancy

Unsafe

Do not take Pemetrex 100mg if you are pregnant because it may cause harm to the unborn baby. Consult your doctor before starting the treatment

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Pemetrex 100mg side effects are

Serious:

  • Blood infection

  • Severe allergic reaction

  • Breathlessness, intense chest pain or cough with bloody sputum

  • Reduced neutrophil granulocytes (white blood cells)

  • Kidney failure

  • Pharyngitis (a sore throat)

  • Abnormal liver function

Common:

  • Fatigue

  • Nausea, vomiting, diarrhea

  • Redness, swelling or sores in the mouth

  • Loss of appetite, sensation

  • Reduced hemoglobin level

  • Increased skin pigmentation

  • Watery and inflamed eyes, taste change

  • Fever

  • Muscle weakness

  • Dehydration

  • Constipation

  • Skin rash

  • Hair loss

Expert tips

  • Discuss fertility concerns with your doctor, as men are advised not to father a child during treatment and for 3 months afterward.

  • Avoid pregnancy planning during this period and follow medical guidance on fertility issues.

  • If you develop any symptoms or side effects, contact your doctor immediately.

  • Inform your doctor if you have received any radiotherapy, vaccines, or other medications before starting Pemetrex 100mg, as these may affect its effectiveness or increase side effects.

  • Share your medical history, especially if you have or previously had heart disease, kidney problems, or liver issues, before beginning treatment.

FAQs about Pemetrex 100mg Injection

Q1.

What should I tell my doctor before starting Pemetrex 100mg? 

Before starting Pemetrex 100mg, you should tell your doctor about any medical conditions you have, especially kidney or liver problems, as well as any medications you are taking, including over-the-counter drugs and supplements.

Q2.

Can children or adults take Pemetrex 100mg?

No, Pemetrex 100mg is not recommended for children or adults under 18 years. Talk with your doctor for more information. 

Q3.

What is the recommended blood test schedule while using Pemetrex 100mg?

You will need to have regular blood tests while taking Pemetrex 100mg to monitor your blood cell counts, blood uric acid level, and kidney function.

Q4.

Can I continue my normal activities while on Pemetrex 100mg? 

It depends on your circumstances and how you feel. You should discuss your activities and any concerns with your healthcare provider.

Q5.

What is the method of administering Pemetrex 100mg? 

A healthcare provider gives Pemetrex 100mg as an intravenous (IV) injection. The dose and frequency of the injections will depend on the patient's condition and other factors.

Q6.

Why do I feel nauseous while taking Pemetrex 100mg? 

Nausea is a common side effect of chemotherapy drugs, including Pemetrex 100mg. This happens because chemotherapy drugs can affect the lining of the stomach, leading to nausea and vomiting.

Fact Box

Molecule name

Pemetrexed

Therapeutic class

Anti-Cancer

Pharmacological class

Antifolate agent

Indication: 

  • Non-small cell lung carcinoma

  • Malignant pleural mesothelioma

References

  1. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs,7th edition, 2013, 863.
  2. Eagle Pharmaceuticals, US Food and Drug Administration, [ Revised on Feb 2020] [ Accessed on 27 - March - 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/209472s000lbl.pdf 
  3. Seacross Pharmaceuticals Ltd, Electronic medicines compendium (emc), [ Accessed on 27 - March - 2023], https://www.medicines.org.uk/emc/files/pil.8887.pdf

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

Did you find this information helpful?

Author Details
Aswini Priya Velmurugan

Written By

Aswini Priya Velmurugan

PG in Biotechnology


Dr. Tejashwin Adiga

Reviewed By

Dr. Tejashwin Adiga

MBBS


Last updated : 29 Apr 2026 | 05:02 AM (IST)

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