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Pemetrex 100mg Injection
Last updated on 29 Apr 2026 | 05:02 AM (IST)
₹686
MRP: ₹857.3
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1 VIAL(s)
Pemetrex 100mg Injection
Salt Composition
PEMETREXEDMarketer
BDR PHARMACEUTICALS INTERNATIONALS PVT LTD
Prepaid Only. Non-Returnable.
20% OFF
₹686
MRP: ₹857.30
Inclusive of all taxes
20% Off
Salt Composition
PEMETREXEDMarketer
BDR PHARMACEUTICALS INTERNATIONALS PVT LTD
Prepaid Only. Non-Returnable.
Dispatch: Today
Care delivered without the wait. Your order is prioritized for rapid dispatch to ensure it reaches your doorstep on time.
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Introduction
Pemetrex 100 mg/vial (injection) is an anticancer medicine containing the active ingredient Pemetrexed. It belongs to the medication class known as an antifolate agent. Pemetrex injection uses in the treat non-small cell lung cancer and malignant pleural mesothelioma (cancers of the lungs and chest). This Injection is given alone or in combination with another anticancer medicine, such as cisplatin. Your doctor may prescribe corticosteroids, folic acid, and vitamin B12 to limit the side effects.
Blood tests will be taken before each infusion to determine whether your kidney and liver functions are adequate and whether you have enough blood cells to receive this medicine. Before starting treatment with Pemetrex 100mg Injection, it is very important to tell your physician if you are currently or previously had any medical conditions of kidney problems, heart disorders, fluid accumulation in the lungs, Report your doctor if you recently had or currently having radiotherapy or any vaccination before taking this medication.
Inform your doctor immediately if you are planning to get pregnant or think you may be pregnant. Use effective birth control during the treatment and at least six months after the last dose of Pemetrex 100mg Injection. In men, it is recommended not to father a child during and up to 3 months after the treatment. So it is advised to get suggestions about fertility concerns from your doctor. This medication is not recommended for adolescents and children under 18 years of age.
Uses
Pemetrex 100mg uses are
Malignant pleural mesothelioma
Non-small cell lung carcinoma
How Pemetrex 100mg Injection works
Pemetrex 100mg inhibits the mechanism required for cell division and replication by blocking specific enzymes involved in folate metabolism (essential for cell replication) and DNA synthesis, which will prevent the cancer cells from growing and multiplying.
Interaction of Pemetrex 100mg Injection with other drugs
Inform your healthcare provider about all your medicines, including prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products. Certain medications such as may interact with Pemetrex 100mg and reduce effectiveness by causing undesirable side effects.
Storage conditions
Keep the tablets away from light and moisture.
Store refrigerated at 2°C to 8°C.
Keep the tablets out of the reach of children and animals.
How to use Pemetrex 100mg Injection
Pemetrex 100mg injection is administered as an intravenous infusion into the vein. If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administer. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.
Safety Advice for Pemetrex 100mg Injection
Breast Feeding
It is unsafe to breastfeed while taking Pemetrex 100mg because it can cause toxicity to the baby. If you are breastfeeding a baby, it has to be discontinued. Please consult your physician for more advice.
Alcohol
It is unknown whether consuming alcohol while taking a Pemetrex 100mg injection is safe. Please speak with your physician.
Liver
Inform your physician about any underlying liver disorders before taking Pemetrex 100mg, as this medication should be used with caution in liver disease patients.
Lungs
Consult your doctor if you experience any symptoms like; shortness of breath, blockage, or inflammation in the lining of the lung while taking Pemetrex 100mg injection
Driving
While taking Pemetrex 100mg injection, it is unsafe to drive or use machines because it may cause nausea, fatigue, vomiting, etc. Talk to your doctor for more information.
Pregnancy
Do not take Pemetrex 100mg if you are pregnant because it may cause harm to the unborn baby. Consult your doctor before starting the treatment
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Pemetrex 100mg side effects are
Serious:
Blood infection
Severe allergic reaction
Breathlessness, intense chest pain or cough with bloody sputum
Reduced neutrophil granulocytes (white blood cells)
Kidney failure
Pharyngitis (a sore throat)
Abnormal liver function
Common:
Fatigue
Nausea, vomiting, diarrhea
Redness, swelling or sores in the mouth
Loss of appetite, sensation
Reduced hemoglobin level
Increased skin pigmentation
Watery and inflamed eyes, taste change
Fever
Muscle weakness
Dehydration
Constipation
Skin rash
Hair loss
Expert tips
Discuss fertility concerns with your doctor, as men are advised not to father a child during treatment and for 3 months afterward.
Avoid pregnancy planning during this period and follow medical guidance on fertility issues.
If you develop any symptoms or side effects, contact your doctor immediately.
Inform your doctor if you have received any radiotherapy, vaccines, or other medications before starting Pemetrex 100mg, as these may affect its effectiveness or increase side effects.
Share your medical history, especially if you have or previously had heart disease, kidney problems, or liver issues, before beginning treatment.
FAQs about Pemetrex 100mg Injection
Q1.
What should I tell my doctor before starting Pemetrex 100mg?
Before starting Pemetrex 100mg, you should tell your doctor about any medical conditions you have, especially kidney or liver problems, as well as any medications you are taking, including over-the-counter drugs and supplements.
Q2.
Can children or adults take Pemetrex 100mg?
No, Pemetrex 100mg is not recommended for children or adults under 18 years. Talk with your doctor for more information.
Q3.
What is the recommended blood test schedule while using Pemetrex 100mg?
You will need to have regular blood tests while taking Pemetrex 100mg to monitor your blood cell counts, blood uric acid level, and kidney function.
Q4.
Can I continue my normal activities while on Pemetrex 100mg?
It depends on your circumstances and how you feel. You should discuss your activities and any concerns with your healthcare provider.
Q5.
What is the method of administering Pemetrex 100mg?
A healthcare provider gives Pemetrex 100mg as an intravenous (IV) injection. The dose and frequency of the injections will depend on the patient's condition and other factors.
Q6.
Why do I feel nauseous while taking Pemetrex 100mg?
Nausea is a common side effect of chemotherapy drugs, including Pemetrex 100mg. This happens because chemotherapy drugs can affect the lining of the stomach, leading to nausea and vomiting.
Fact Box
Molecule name | Pemetrexed |
Therapeutic class | Anti-Cancer |
Pharmacological class | Antifolate agent |
Indication: |
|
References
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs,7th edition, 2013, 863.
- Eagle Pharmaceuticals, US Food and Drug Administration, [ Revised on Feb 2020] [ Accessed on 27 - March - 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/209472s000lbl.pdf
- Seacross Pharmaceuticals Ltd, Electronic medicines compendium (emc), [ Accessed on 27 - March - 2023], https://www.medicines.org.uk/emc/files/pil.8887.pdf
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details

Written By
Aswini Priya Velmurugan
PG in Biotechnology

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 29 Apr 2026 | 05:02 AM (IST)

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