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Pentrelief 30mg Injection 1ml
Last updated on 31 Mar 2026 | 09:30 AM (IST)
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1 AMPOULE(s) OF 1ML
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MRP: ₹42.19
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Introduction to Pentrelief 30mg Injection 1ml
Pentrelief 30mg injection contains an active component such as Pentazocine lactate. It is a medication used for pain management. After surgical procedures, patients often experience pain as part of the recovery process. It can help manage the pain during this period. It might be used to alleviate pain caused by injuries, such as fractures, sprains, or soft tissue damage. It can be used as part of a pain management plan for cancer patients. It may be considered for chronic pain conditions like severe back pain, neuropathic pain, and other conditions where non-opioid medications have proven ineffective. This medication may sometimes be used during labor to help manage the pain associated with contractions. It can also be administered to reduce pain and anxiety associated with certain medical procedures, such as wound care or dressing changes.
Individuals who have a known hypersensitivity or allergy to Pentrelief 30mg injection or any of its components should not use this medication. It should be avoided in individuals with severe respiratory conditions or compromised respiratory function. It should be avoided in individuals with conditions that can be worsened by CNS depression, such as head injuries or increased intracranial pressure. It should not be used in combination with MAOIs or within 14 days of discontinuing MAOIs due to the risk of hypertensive crisis. Elderly patients may be more susceptible to this medication's CNS depressant effects and other side effects, so its use should be carefully considered. Pentrelief 30mg injection is an opioid analgesic, and its use in children should be approached with caution and under the guidance of a pediatrician or a healthcare provider
Uses of Pentrelief 30mg Injection 1ml
Pentrelief 30mg injection is used in the following:
- Postoperative pain
- Injury and trauma pain
- Cancer pain
- Chronic pain
- Labor pain
- Painful medical procedures
- Emergency pain relief
- Pain from medical conditions
- Preoperative sedation
- Diagnostic procedures
Therapeutic Effects of Pentrelief 30mg Injection 1ml
Pentrelief 30mg injection involves binding to both kappa opioid receptors as an agonist and mu-opioid receptors as a weak antagonist. This dual activity modulates pain perception and transmission in the central nervous system, relieving pain. Its partial agonist activity at mu receptors relieves pain while limiting the potential for respiratory depression, though it still carries risks of side effects and misuse.
Interaction of Pentrelief 30mg Injection 1ml with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Pentrelief 30mg injection, reducing effectiveness by causing undesirable side effects.
More Information about Pentrelief 30mg Injection 1ml
- Store at room temperature, between 15°C and 30°C
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Pentrelief 30mg Injection 1ml
The common routes of administration of Pentrelief 30mg injection include intramuscular (IM) injection and intravenous (IV) injection. Depending on the situation and the healthcare provider's recommendations, it can be administered through various routes.
Safety Advice for Pentrelief 30mg Injection 1ml
Breast Feeding
Pentrelief 30mg injection passes into breast milk and can affect nursing infants. It's not safe to use this medication while breastfeeding.
Alcohol
Alcohol can enhance the central nervous system depressant effects of Pentrelief 30mg injection , leading to increased drowsiness and respiratory depression, so it is not safe to take this medication with alcohol.
Liver
Pentrelief 30mg injection metabolism may involve the liver, and individuals with severe liver impairment should consult their healthcare provider before using this medication.
Lungs
Pentrelief 30mg injection can depress the respiratory system, potentially causing breathing difficulties, especially in individuals with lung conditions. Inform your healthcare provider about any lung issues you have before taking pentazocine.
Driving
It is not safe to take Pentrelief 30mg injection as it can cause drowsiness, dizziness, and impaired coordination.
Pregnancy
Pentrelief 30mg injection should be used cautiously during pregnancy. It's important to consult your healthcare provider before using this medication while pregnant
Side Effects of Pentrelief 30mg Injection 1ml
Pentrelief 30mg injection causes some side effects like all medications, although not everyone will experience them.
Serious
- Respiratory depression
- Dependence and addiction
- Hypotension
- Central nervous system effects
- Gastrointestinal effects
- Allergic reactions
- Withdrawal
Common
- Drowsiness and dizziness
- Nausea and vomiting
- Sweating
- Constipation
- Dry mouth
- Headache
- Lightheadedness
- Weakness or fatigue
- Mood changes
- Urinary retention
Word of Advice
Inform your healthcare provider of your medical history, allergies, and current medications, as certain conditions or medications can interact with Pentrelief 30mg injection. If you have respiratory issues, consult your healthcare provider due to the risk of respiratory depression. Consider your liver and kidney function, as adjustments to the dosage might be necessary. Those with a history of substance abuse should exercise caution, as it carries the potential for dependence and misuse. Its dosages should be closely monitored and adjusted by your healthcare provider. It is advisable not to stop the medication abruptly, and any changes in mood or mental health should be communicated. Be cautious about accidental overdose and avoid sharing medication. In case of emergencies, know the signs of allergic reactions. Maintain open communication with your healthcare provider, attend follow-up appointments, and educate yourself about the medication for informed decision-making. Always follow your healthcare provider's instructions for this medication's safe and appropriate use.
FAQs about Pentrelief 30mg Injection 1ml
Q1.
What should I do if I miss a dose of Pentrelief 30mg injection?
If you miss a dose, take it as soon as you remember. However, if it's close to the next dose, skip it and continue with your regular dosing schedule.
Q2.
Can Pentrelief 30mg injection be addictive?
Yes, pentazocine has the potential to be habit-forming. To minimize the risk of dependence, take it only as your doctor prescribes, and don't share it with others.
Q3.
How long can I take Pentrelief 30mg injection?
Pentrelief 30mg injection is typically prescribed for short-term pain relief, as its long-term use can increase the risk of side effects, tolerance, and dependence. Your healthcare provider will determine the appropriate duration of treatment based on your condition.
Q4.
Does Pentrelief 30mg injection affect breathing?
Yes, pentazocine can slow down breathing, especially if used in high doses or for prolonged periods. It's essential to discuss any existing breathing issues or lung conditions with your doctor before using this medication.
Q5.
How does Pentrelief 30mg injection compare to other pain medications?
Pentrelief 30mg injection has a unique mechanism of action, acting as a partial agonist and antagonist on certain opioid receptors. It's important to discuss your pain management needs and any previous experiences with pain medications with your doctor to determine the best option for you.
Q6.
Can I adjust the dose of Pentrelief 30mg injection on my own?
No, it's important not to adjust the dose of Pentrelief 30mg injection on your own. Any changes to your dosage should be discussed with your healthcare provider to ensure safe and effective pain management.
Fact Box of Pentrelief 30mg Injection 1ml
Molecule name: Pentazocine lactate | Therapeutic class: Opioid receptor agonist-antagonists. |
Pharmacological class: Analgesics | Indications: 1. Postoperative pain 2. Injury and trauma pain 3. Cancer pain 4. Chronic pain 5. Labor pain 6. Painful medical procedures 7. Emergency pain relief 8. Pain from medical conditions 9. Preoperative sedation 10. Diagnostic procedures |
References
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Opioids, analgesia and pain management, 12th edition, 2011, 509.
- KD Tripathi, Essentials of Medical Pharmacology, Opioid analgesics and antagonists, 7th edition, 2013, 480 - 482.
- Hospira, Inc, US Food and Drug Administration, [Revised on Dec 2016] [ Accessed on 31 August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/016194s079s080lbl.pdf
- Mylan, Electronic medicines compendium (EMC), [ Revised on 22nd Aug 2021] [ Accessed on August 31st, 2023],https://www.medicines.org.uk/emc/product/8832/smpc#gref
Disclaimer
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Author Details
Written By
Dr. Archana Gupta
BDS
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:30 AM (IST)
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