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Phesgo 1200mg/600mg Injection

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Salt Composition : Pertuzumab,trastuzumab

Manufacturer : ROCHE PRODUCTS INDIA PVT LTD

Origin of Medicine : Switzerland

MRP: 535000
Price :460100
You Save :74900 (14%)

1 Vial(s)

Prepaid Only. Non-Returnable

PAP Information :    Buy 1,Get 1 Free. Contact us for latest updates

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Patient Assistance Programs
Know About PAP

Program Overview: ROCHE PRODUCTS INDIA PVT LTD, is dedicated to helping patients in need of Phesgo 1200mg/600mg Injection. The program aims to provide eligible patients with access to the medication at a more affordable cost.

Program Benefits: Purchase 1 vial of Phesgo 1200mg/600mg Injection, and you will receive 1 additional vial for free. Therefore, if eligible, you will have to pay only Rs. 4,60,100 for 2 vials, which is Rs.2,30,050 per vial.

With MrMed's MRP discount of Rs. 74,900 per vial and Roche’s PAP program, the overall savings is over 6 lakhs per purchase.  

Eligibility Criteria: To qualify for the Phesgo Patient Assistance Program (PAP), you must meet specific criteria, including having a valid prescription for tablet containing pertuzumab and trasrtuzumab 1200mg/600mg from a medical oncologist and being an Indian patient with a valid identity card. Eligibility is determined based on the diagnosed condition and program-specific requirements.

Contact Information: If you have any questions or need assistance with the application process, our dedicated patient support team is here to help. You can reach us by phone at 89391 69999 or email us at [email protected].

Please note that MrMed is not involved in the PAP program. They offer free consultations to patients to provide information about the program. Patients eligible for the PAP program by Roche can avail of it without having to purchase the medication from MrMed.

Patient Assistance Programs

Program Overview: ROCHE PRODUCTS INDIA PVT LTD, is dedicated to helping patients in need of Phesgo 1200mg/600mg Injection. The program aims to provide eligible patients with access to the medication at a more affordable cost.

Program Benefits: Purchase 1 vial of Phesgo 1200mg/600mg Injection, and you will receive 1 additional vial for free. Therefore, if eligible, you will have to pay only Rs. 4,60,100 for 2 vials, which is Rs.2,30,050 per vial.

With MrMed's MRP discount of Rs. 74,900 per vial and Roche’s PAP program, the overall savings is over 6 lakhs per purchase.  

Eligibility Criteria: To qualify for the Phesgo Patient Assistance Program (PAP), you must meet specific criteria, including having a valid prescription for tablet containing pertuzumab and trasrtuzumab 1200mg/600mg from a medical oncologist and being an Indian patient with a valid identity card. Eligibility is determined based on the diagnosed condition and program-specific requirements.

Contact Information: If you have any questions or need assistance with the application process, our dedicated patient support team is here to help. You can reach us by phone at 89391 69999 or email us at [email protected].

Please note that MrMed is not involved in the PAP program. They offer free consultations to patients to provide information about the program. Patients eligible for the PAP program by Roche can avail of it without having to purchase the medication from MrMed.

Introduction to Phesgo 1200mg/600mg Injection

Phesgo 1200mg/600mg Injection is a targeted therapy containing the active constituents pertuzumab and trasrtuzumab. It is used to treat a type of breast cancer (human epidermal growth factor receptor 2 positive breast cancer) that has spread to other parts of the body (metastasized) or cancer that has come back after the treatment. It will also be given before or after the surgery if the cancer has not metastasized. Cancer occurs when cells begin to grow abnormally in an uncontrolled manner.

Before taking Phesgo 1200mg/600mg Injection, talk to the physician if you have heart problems, have had radiotherapy, or have allergic conditions. This medication is not recommended for adolescents and children under 18. In patients with early-stage HER2-positive breast cancer, adding pertuzumab or trastuzumab to standard chemotherapy can reduce the risk of recurrence and improve disease-free survival.


Uses of Phesgo 1200mg/600mg Injection

Phesgo 1200mg/600mg Injection is used to manage the following conditions:

  • Breast cancer
  • Non-small cell lung cancer

Therapeutic Effects of Phesgo 1200mg/600mg Injection

Human epidermal growth factor receptor 2 protein is largely present in some cancer cells and stimulates the growth of cancer cells. Phesgo 1200mg/600mg Injection binds selectively to the HER2 receptors on breast cancer cells' surface, blocks them from receiving growth signals, and stops the cancer cells' growth.


Interaction of Phesgo 1200mg/600mg Injection with other drugs

Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Phesgo 1200mg/600mg Injection and reduce effectiveness by causing undesirable side effects.


More Information about Phesgo 1200mg/600mg Injection

  • Store in a refrigerator between 2°C and 8°C (36°F and 46°F).
  • It should not be frozen.
  • Keep it in its original packaging until it is ready to be used.
  • Keep out of the reach of children and pets.

How to consume Phesgo 1200mg/600mg Injection

Phesgo 1200mg/600mg Injection is a medication administered intravenously (IV) by a healthcare professional. It is important to follow the healthcare provider's instructions regarding the dosage and administration of medication. Do not double the dose to make up for missed doses.


Safety Advices for Phesgo 1200mg/600mg Injection

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Pregnancy

  

Phesgo 1200mg/600mg Injection may harm the developing fetus, so it is unsafe to use it during pregnancy.

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Breast Feeding

  

It is unknown whether Phesgo 1200mg/600mg Injection is excreted in human milk. So breastfeeding women should consult their doctor before taking it.

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Lungs

  

Phesgo 1200mg/600mg Injection can cause side effects, and the safety of their use in the lungs depends on several factors. Patients should consult their doctor if they have any pre-existing health condition before taking this medication.

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Liver

  

Patients with pre-existing liver disease or impaired liver function may be at increased risk for the potential side effects of Phesgo 1200mg/600mg Injection, including liver toxicity. So patients should discuss it with their healthcare provider before taking it.

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Alcohol

  

Alcohol use can negatively affect the immune system, and patients receiving Phesgo 1200mg/600mg Injection may already have compromised immune systems due to their medical condition or treatment. Therefore, it is generally recommended that patients limit their alcohol consumption or avoid alcohol entirely while receiving it.

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Driving

  

Patients should always monitor their response to the Phesgo 1200mg/600mg Injection medication and be cautious when driving or operating machinery if they experience any side effects that may impair their ability to do so safely.


Side Effects of Phesgo 1200mg/600mg Injection

Like all medications, Phesgo 1200mg/600mg Injections cause some side effects, although not everyone will experience them. 

Serious:

  • Pulmonary toxicity (interstitial lung disease or pneumonitis)
  • Infusion-related reactions
  • Hypersensitivity reactions
  • Liver toxicity
  • Immune system effects
  • Severe allergic reactions
  • Gastrointestinal perforation (rare)
  • Reduced blood platelets or white blood cell counts

Common:

  • Nausea and vomiting
  • Diarrhea
  • Fatigue
  • Hair loss
  • Rash or itching
  • Muscle pain or weakness
  • Headache
  • Difficulty sleeping
  • Loss of appetite

Word of Advice

If you have prescribed Phesgo 1200mg/600mg Injection, or any other medication, it is important to carefully read and understand the warnings and precautions associated with the medication. Patients should be monitored for signs of an allergic reaction, such as rash, itching, or swelling, and should seek immediate medical attention if these symptoms occur. It should be used with caution in patients with severe renal impairment. Talk to the physician if you have heart problems, have had radiotherapy, or have allergic conditions. Use effective birth control during the treatment and at least seven months after the last dose. Always maintain a healthy and balanced diet to support your overall health and well-being.


FAQs

Q 1. Can Phesgo 1200mg/600mg Injection cause infertility?

Phesgo 1200mg/600mg Injection can affect fertility in some patients, although the extent of this effect is not well-understood. Women who wish to preserve their fertility should discuss their options with their healthcare provider before starting treatment with these drugs.

Q 2. Can Phesgo 1200mg/600mg Injection be used together with chemotherapy?

Yes, Phesgo 1200mg/600mg Injection are often combined with chemotherapy to treat HER2-positive breast cancer. This combination therapy effectively reduces the risk of recurrence and improves overall survival in patients with HER2-positive breast cancer.

Q 3. Can I take Phesgo 1200mg/600mg Injection if I have TB?

If you have active tuberculosis (TB) infection, Phesgo 1200mg/600mg Injection should not be used until the TB infection has been treated and is under control. These drugs can suppress the immune system, worsening TB or other infections.

Q 4. Can Phesgo 1200mg/600mg Injection cause skin reactions?

Yes, Phesgo 1200mg/600mg Injection can cause skin reactions, including rash, dry skin, and itching. In some cases, these skin reactions can be severe and require treatment. Patients should promptly report any new or worsening skin symptoms to their healthcare provider.

Q 5. Can Phesgo 1200mg/600mg Injection affect blood counts?

Yes, Phesgo 1200mg/600mg Injection can affect blood counts and may increase the risk of anemia, thrombocytopenia, and neutropenia. These blood disorders can cause symptoms such as fatigue, weakness, and an increased risk of infections or bleeding. Patients receiving this medication should check their blood counts regularly.

Q 6. Can Phesgo 1200mg/600mg Injection be used in older adults?

Yes, Phesgo 1200mg/600mg Injection can be used in older adults. However, older adults may be at increased risk of side effects like heart-related complications or infections. Healthcare providers may need to adjust the dose or monitor more closely for potential side effects in older patients.

Q 7. Can Phesgo 1200mg/600mg Injection be used in men with breast cancer?

Yes, Phesgo 1200mg/600mg Injection can be used in men with HER2-positive breast cancer. Breast cancer is rare in men, accounting for less than 1% of all breast cancer cases. However, HER2-positive breast cancer is more common in men than in women with breast cancer.


Fact Box of Phesgo 1200mg/600mg Injection

Molecule name: Pertuzumab, Trastuzumab

Therapeutic class: Anticancer

Pharmacological class: Monoclonal antibodies

Indications: 

1. Non-small cell lung cancer

2. Breast cancer


References

  1. Roche products limited, Electronic medicines compendium (EMC), [Revised on Jan 2022] [ Accessed on 03/05/2023], https://www.medicines.org.uk/emc/files/pil.11989.pdf
  2. zhu Chenjing et al.; Safety and efficacy evaluation of pertuzumab in patients with solid tumors; Medicine; [Published on May 2017]; [Accessed on 03/05/2023] https://journals.lww.com/md-journal/fulltext/2017/05190/safety_and_efficacy_evaluation_of_pertuzumab_in.19.aspx
  3. Sandra M Swain et al; Pertuzumab, Trastuzumab, and docetaxel in HER2-positive metastatic breast cancer; The New England Journal of Medicine; [Published on Feb 2015]; [Accessed on 03/05/203]; https://pubmed.ncbi.nlm.nih.gov/25693012/

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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