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Picasa GR 100mg Tablet
Last updated on 10 Aug 2026 | 06:36 AM (IST)
₹2675
MRP: ₹6227.7
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Picasa GR 100 mg Tablet is a prescription medicine used in the treatment of idiopathic pulmonary fibrosis (IPF), a condition that causes progressive scarring of the lungs. It contains pirfenidone in a modified-release form, which works by reducing inflammation and slowing the formation of fibrotic tissue in the lungs. Picasa GR is taken under medical supervision as part of a long-term respiratory care plan.
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Introduction
Picasa GR 100mg Tablet belongs to a class of drugs called azole antifungals containing the active ingredient Posaconazole. It is used to treat and prevent certain fungal infections. The medication is commonly prescribed for preventing and treating invasive fungal infections in patients with weak immune systems, such as those undergoing cancer chemotherapy, stem cell transplantation, or those with HIV/AIDS. It also treats certain fungal infections in individuals who cannot tolerate or have not responded to other antifungal treatments.
This drug is contraindicated in individuals with known hypersensitivity or allergy to other antifungal medications like ketoconazole, fluconazole, itraconazole, or voriconazole. Before taking Picasa GR 100mg Tablet, it is necessary to consult with your physician if you have certain heart conditions like abnormal heart rhythm (long QTc interval), weakness of the heart muscle, heart failure, or any heart rhythm disturbances, or if you experience severe kidney problems, diarrhea or vomiting while on treatment with this drug, it's important to inform your physician immediately, as these conditions may affect the medicine's effectiveness.
Picasa GR 100mg Tablet may affect the levels of potassium, magnesium, or calcium in the blood. If you have any problems with these electrolyte levels, your doctor will monitor you closely during treatment. If you are taking medications such as vincristine, vinblastine, or any other vinca alkaloids drugs which are used to treat cancer, you should also inform your physician before initiating the treatment. If you are pregnant, use this drug only if your doctor advises. Consuming this drug while breastfeeding may be unsafe because it passes into breast milk and affects the child. Do not breastfeed while taking this medicine.
Uses
Treatment of fungal infections
How Picasa GR 100mg Tablet Works
Picasa GR 100mg Tablet works by inhibiting the synthesis of ergosterol, a vital component of the fungal cell membrane. This disruption weakens the membrane, leading to cell death, and effectively treats fungal infections.
Interaction of Picasa GR 100mg Tablet with other drugs
Taking Picasa GR 100mg Tablet (itraconazole) with any of the following medicines can change the effect of either of them and may increase the risk of serious side effects.
Terfenadine, Astemizole, or Cisapride (Oral Route) Life-threatening
Do not use together.
Concomitant use may cause serious heart rhythm disturbances.
Simvastatin or Lovastatin (Oral Route) Life-threatening
Avoid using together.
Itraconazole may increase statin levels and raise the risk of severe muscle damage.
Midazolam or Triazolam (Oral Route) Life-threatening
Do not take together.
Concomitant use may increase sedation and cause breathing problems.
Warfarin (Oral Route) Moderate
Use with caution.
Itraconazole may increase the effect of warfarin and raise the risk of bleeding.
Digoxin (Oral Route) Moderate
Use under medical supervision.
Itraconazole may increase digoxin levels and increase the risk of toxicity.
Rifampicin (Oral Route) Life-threatening
Do not use together.
Rifampicin may reduce itraconazole levels and make the treatment ineffective.
Carbamazepine or Phenytoin (Oral Route) Life-threatening
Avoid using together.
These medicines may decrease itraconazole levels and reduce its effectiveness.
Antacids or Proton Pump Inhibitors such as Omeprazole (Oral Route) Moderate
Use with caution.
These medicines may reduce the absorption of itraconazole and decrease its effectiveness.
Storage Conditions
Store Picasa GR 100mg Tablet below (30°C).
Protect from light and moisture.
How to consume Picasa GR 100mg Tablet
Take the Picasa GR 100mg Tablet as your physician advises. Usually, the tablets will be taken with or without food. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.
Safety Advice
Breast Feeding
Taking Picasa GR 100mg Tablet while breastfeeding may be unsafe because it passes into breast milk and affects the child. Do not breastfeed while taking this medicine.
Alcohol
It is unknown whether consuming alcohol during treatment with Picasa GR 100mg Tablet is safe. Please speak with your physician.
Liver
Inform your doctor if you have liver disease because the Picasa GR 100mg Tablet should be used cautiously with a liver condition.
Lungs
It is unknown whether Picasa GR 100mg Tablet is safe for patients with lung problems. Inform your physician if you have lung disease before starting the treatment.
Driving
Some side effects of Picasa GR 100mg Tablet may impair your ability to drive or operate machinery safely. It is unsafe to consume this drug.
Pregnancy
If you are pregnant, suspecting, or planning for the pregnancy, consult your doctor for more advice before taking Picasa GR 100mg Tablet.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
Serious allergic reactions
Skin rash or ulcers in the mouth, bruising, pale skin
Yellow discoloration of eyes and skin, abdominal pain
Common
Loss of appetite
Low white blood cells
Mild increase in blood pressure
Diarrhea
Nausea, vomiting
Rectal discomfort
Expert Tips
Your doctor will review your medical history and may perform tests to check if this medicine is suitable for you.
Follow your doctor's instructions for proper use and monitoring during treatment.
Regular monitoring may be required to track your progress.
Discuss any questions or concerns about the medicine or its side effects with your doctor.
FAQs about Picasa GR 100mg Tablet
Q1.
What conditions does Picasa GR 100mg Tablet treat?
Picasa GR 100mg Tablet treats and prevents invasive fungal infections caused by certain fungi, such as Aspergillus and Candida species. It is commonly prescribed for patients undergoing cancer chemotherapy, stem cell transplantation, or those with HIV/AIDS.
Q2.
What formulations are available for Picasa GR 100mg Tablet?
Picasa GR 100mg Tablet is available in different formulations, including oral suspension, syrup, delayed-release tablets, and intravenous (IV) infusion. The specific formulation and dosing will depend on the individual's condition and the physician's recommendation.
Q3.
Are there any precautions or contraindications for using Picasa GR 100mg Tablet?
Individuals who have had an allergic reaction to other azole antifungal medications, those with certain heart conditions, liver problems, or abnormal potassium, magnesium, or calcium levels in the blood should exercise caution or avoid Picasa GR 100mg Tablet. Always inform your physician about your medical history before initiating the treatment.
Q4.
Are there any side effects associated with Picasa GR 100mg Tablet?
Common side effects of Picasa GR 100mg Tablet include nausea, diarrhea, headache, and abdominal pain. Serious side effects are rare but may also include liver problems and allergic reactions. If you experience any concerning side effects, contact your physician immediately.
Q5.
Can pregnant or breastfeeding individuals take Picasa GR 100mg Tablet?
Picasa GR 100mg Tablet may not be safe during pregnancy, and its use during breastfeeding is not recommended. If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of this drug with your doctor.
Fact Box
Molecule name: Posaconazole | Therapeutic class: Antifungal |
Pharmacological class: Azole derivative | Indications: Treatment of fungal infections |
References
- Merck Sharp & Dohme (UK) Limited, Electronic medicines compendium (EMC), [Revised on June 2023] [ Accessed on 20th July 2023], https://www.medicines.org.uk/emc/files/pil.5388.pdf
- Merck & Co. Inc, US FDA, [Revised on Dec 2016] [Accessed on 20th July 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/022003s018s020,0205053s002s004,0205596s001s003lbl.pdf
- KD Tripathi, Antifungal drugs, Essentials of Medical Pharmacology, 7th Edition, 2013, 795.
- Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Antifungal agents, 12th edition, 2011, 1581.
Disclaimer
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Author Details
Written By
Dr. B. Deiva
Pharm D
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 10 Aug 2026 | 06:36 AM (IST)
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