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Posatral 300mg Tablet
Last updated on 02 Apr 2026 | 07:22 AM (IST)
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Introduction
Posatral 300mg Tablet belongs to a class of drugs called azole antifungals containing the active ingredient Posaconazole. It is used to treat and prevent certain fungal infections. The medication is commonly prescribed for preventing and treating invasive fungal infections in patients with weak immune systems, such as those undergoing cancer chemotherapy, stem cell transplantation, or those with HIV/AIDS. It also treats certain fungal infections in individuals who cannot tolerate or have not responded to other antifungal treatments.
This drug is contraindicated in individuals with known hypersensitivity or allergy to other antifungal medications like ketoconazole, fluconazole, itraconazole, or voriconazole. Before taking Posatral 300mg Tablet, it is necessary to consult with your physician if you have certain heart conditions like abnormal heart rhythm (long QTc interval), weakness of the heart muscle, heart failure, or any heart rhythm disturbances, or if you experience severe kidney problems, diarrhea or vomiting while on treatment with this drug, it's important to inform your physician immediately, as these conditions may affect the medicine's effectiveness.
Posatral 300 mg Tablet may affect the levels of potassium, magnesium, or calcium in the blood. If you have any problems with these electrolyte levels, your doctor will monitor you closely during treatment. If you are taking medications such as vincristine, vinblastine, or any other vinca alkaloid drugs which are used to treat cancer, you should also inform your physician before initiating the treatment. If you are pregnant, use this drug only if your doctor advises. Taking this drug while breastfeeding may be unsafe because it passes into breast milk and affects the child. Do not breastfeed while taking this medicine. Posatral tablet price varies on the retailer and Location.
Uses
Posatral 300mg uses:
- Treatment of fungal infections
How Posatral 300mg Tablet Works
Posatral 300mg Tablet works by inhibiting the synthesis of ergosterol, a vital component of the fungal cell membrane. This disruption weakens the membrane, leading to cell death, and effectively treats fungal infections.
Interaction of Posatral 300mg Tablet with other drugs
Inform your physician about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications such as terfenadine, astemizole, cisapride, pimozide, halofantrine, and quinidine may interact with Posatral 300mg Tablet and reduce effectiveness by causing undesirable side effects.
Storage Conditions
- Store Posatral 300mg Tablet below (30°C).
- Protect from light and moisture.
How to Use Posatral 300mg Tablet
Posatral 300mg Tablet can be administered only as an intravenous injection into a vein by your physician in a hospital setting. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.
Safety Advice for Posatral 300mg Tablet
Breast Feeding
Taking Posatral 300mg Tablet while breastfeeding may be unsafe because it passes into breast milk and affects the child. Do not breastfeed while taking this medicine.
Alcohol
It is unknown whether consuming alcohol during treatment with Posatral 300mg Tablet is safe. Please speak with your physician.
Liver
Inform your doctor if you have liver disease because the Posatral 300mg Tablet should be used cautiously with a liver condition.
Lungs
It is unknown whether Posatral 300mg Tablet is safe for patients with lung problems. Inform your physician if you have lung disease before starting the treatment.
Driving
Some side effects of Posatral 300mg Tablet may impair your ability to drive or operate machinery safely. It is unsafe to administer this drug.
Pregnancy
If you are pregnant, suspecting, or planning for a pregnancy, consult your doctor for more advice before taking Posatral 300mg Tablet.
Side Effects
Posatral 300mg side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Serious allergic reactions
- Skin rash or ulcers in the mouth, bruising, pale skin
- Yellow discoloration of eyes and skin, abdominal pain
Common
- Loss of appetite
- Low white blood cells
- Mild increase in blood pressure
- Diarrhea
- Nausea, vomiting
- Rectal discomfort
Expert tips
-
Your doctor will review your medical history and may run tests to confirm if Posatral 300mg Tablet is right for you.
-
You will receive guidance on the correct way to take the medicine and how your progress will be monitored during treatment.
-
If you have doubts about the medicine or its possible side effects, consult your doctor for proper clarification.
FAQs about Posatral 300mg Tablet
Q1.
What conditions does Posatral 300mg Tablet treat?
Posatral 300mg Tablet treats and prevents invasive fungal infections caused by certain fungi, such as Aspergillus and Candida species. It is commonly prescribed for patients undergoing cancer chemotherapy, stem cell transplantation, or those with HIV/AIDS.
Q2.
What formulations are available for Posatral 300mg Tablet?
Posatral 300mg Tablet is available in different formulations, including oral suspension, syrup, delayed-release tablets, and intravenous (IV) infusion. The specific formulation and dosing will depend on the individual's condition and the physician's recommendation.
Q3.
Are there any precautions or contraindications for using Posatral 300mg Tablet?
Individuals who have had an allergic reaction to other azole antifungal medications, those with certain heart conditions, liver problems, or abnormal potassium, magnesium, or calcium levels in the blood should exercise caution or avoid Posatral 300mg Tablet. Always inform your physician about your medical history before initiating the treatment.
Q4.
Are there any side effects associated with Posatral tablet 300 mg?
Common side effects of Posatral Tablet 300 mg include nausea, diarrhea, headache, and abdominal pain. Serious side effects are rare but may also include liver problems and allergic reactions. If you experience any concerning side effects, contact your physician immediately.
Q5.
Can pregnant or breastfeeding individuals take Posatral 300mg Tablet?
Posatral 300mg Tablet may not be safe during pregnancy, and its use during breastfeeding is not recommended. If you are pregnant, planning to become pregnant, or breastfeeding, discuss the risks and benefits of this drug with your doctor.
Fact Box
|
Molecule name: | Posaconazole |
|
Therapeutic class: | Antifungal |
|
Pharmacological class: | Azole derivative |
| Indications: |
Treatment of fungal infections |
References
- Merck Sharp & Dohme (UK) Limited, Electronic medicines compendium (EMC), [Revised on June 2023] [ Accessed on 20th July 2023], https://www.medicines.org.uk/emc/files/pil.5388.pdf
- Merck & Co. Inc, US FDA, [Revised on Dec 2016] [Accessed on 20th July 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/022003s018s020,0205053s002s004,0205596s001s003lbl.pdf
- KD Tripathi, Antifungal drugs, Essentials of Medical Pharmacology, 7th Edition, 2013, 795.
- Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Antifungal agents, 12th edition, 2011, 1581.
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details
Written By
Dr. Vijayalakshmi N.
BDS
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 02 Apr 2026 | 07:22 AM (IST)
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