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Posiact 100mg Injection
Last updated on 31 Mar 2026 | 09:29 AM (IST)
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Introduction to Posiact 100mg Injection
Posiact 100mg Injection is an anticancer drug with the ingredient Etoposide. It belongs to the medication class known as cytostatic. It is used to treat certain types of cancers such as testicular cancer, small-cell lung cancer, acute myeloid leukemia (blood cancer), tumor in the lymphatic system (Hodgkin’s lymphoma, non-Hodgkin’s lymphoma), and ovarian cancer in adults.
Talk to your doctor if you had or currently having radiotherapy or chemotherapy. Report to your doctor if you have any infections or low levels of protein (albumin) in your blood. Posiact 100mg Injection should not be taken if you have recently been vaccinated with yellow fever or any live vaccines. Before starting treatment with this medicine, it is very important to tell your physician if you currently or previously had any medical conditions of kidney problems or liver disorders.
Both women and men should use effective birth control during the treatment and at least 6 months after the last dose. In men, it is recommended not to father a child during and up to 6 months after the treatment. So it is advised to get suggestions about fertility concerns from your doctor. Administration of the Posiact 100mg Injection may cause a reduction in the level of blood cells and increase the risk of developing infections. So, your doctor may perform blood tests regularly to monitor your kidney and liver function. It is unknown whether it is safe to use on a child.
Uses of Posiact 100mg Injection
- Testicular cancer
- Small-cell lung cancer
- Acute myeloid leukemia (blood cancer)
- Hodgkin’s lymphoma and non-Hodgkin’s lymphoma
- Ovarian cancer
Therapeutic Effects of Posiact 100mg Injection
Posiact 100mg Injection works by inhibiting the activity of topoisomerase II (essential for cell replication) and DNA synthesis, which will prevent cancer cells from growing and multiplying, ultimately leading to cell death.
Interaction of Posiact 100mg Injection with other drugs
Inform your healthcare provider about all your medicines, including prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products. Certain medications such as Ciclosporin, Phenytoin, Phenobarbitone, Warfarin, Anthracyclines, Aspirin, and Fosphenytoin may interact with Posiact 100mg Injection and reduce effectiveness by causing undesirable side effects.
More Information about Posiact 100mg Injection
- Keep Posiact 100mg Injection out of sight and reach of children.
- Store at a controlled room temperature between 15°C to 30°C.
- Store in the original package
- Do not refrigerate or freeze.
How to consume Posiact 100mg Injection
Posiact 100mg Injection is taken on an empty stomach with a glass of water. Avoid chewing, breaking, or crushing it. Your physician will choose the dosage based on your medical condition because it differs for each person.
Safety Advice for Posiact 100mg Injection
Breast Feeding
It is unsafe to breastfeed while taking Posiact 100mg Injection because it can cause toxicity to the baby. Please consult your physician for more advice.
Alcohol
It is unknown if drinking alcohol while taking an Posiact 100mg Injection is safe. Please speak with your physician.
Liver
You need to tell your doctor if you have any liver disorders before taking Posiact 100mg Injection. Your doctor may perform blood tests regularly to monitor your condition. Consult your doctor for more information.
Lungs
Consult your doctor if you experience any lung-related symptoms like; shortness of breath or lung inflammation while taking an Posiact 100mg Injection.
Driving
Driving while taking an Posiact 100mg Injection is unsafe because this medicine can cause tiredness, lightheadedness, or dizziness.
Pregnancy
Do not take this Posiact 100mg Injection if you are pregnant because it may cause harm to the unborn baby. Consult your doctor before starting the treatment.
Side Effects of Posiact 100mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious
- Severe allergic reactions (swelling of tongue, or throat, breathing difficulties, rash, flushing, fast heartbeat)
- Irregular heartbeat (arrhythmia)
- Blood disorder
- Hepatotoxicity (damage to the liver)
- Acute leukemia
Common
- Nausea, vomiting
- Loss of appetite
- Abdominal pain
- Constipation, diarrhea
- Changes in skin color
- Weakness
- Asthenia (feeling weak)
- Temporary hair loss
- High or low blood pressure
- Dizziness
- Redness of the skin
- Sore lips, throat, or mouth ulcers
Word of Advice
Discuss your fertility problem with the doctor since, in men, it is advised not to father a child during and after the 6 months of treatment. So it is advised to get suggestions about fertility concerns. Avoid planning for the pregnancy. If you experience any symptoms mentioned as a side effect, consult your doctor immediately. Notify your doctor immediately if you have undergone or are taking or planning any radiotherapy or chemotherapy. Inform your doctor immediately if you took any vaccines inducing yellow fever and live vaccine and other medications before starting with Posiact 100mg Injection because it might reduce the effectiveness of this medicine and may cause side effects. Inform your doctor if you have or had any history of heart disease, kidney problems, or liver problems.
FAQs about Posiact 100mg Injection
Q1.
What should I tell my doctor before starting Posiact 100mg Injection?
Before starting Posiact 100mg Injection, you should tell your doctor about any medical conditions you have, especially kidney or liver problems, and any medications you are taking, including over-the-counter drugs and supplements. Inform your doctor if you had or are currently planning to take radiotherapy or chemotherapy. If you have low levels of protein (albumin) in your blood, it has to be notified to the doctor.
Q2.
How often do I need to have blood tests while on Posiact 100mg Injection?
You will need regular blood tests while taking Posiact 100mg Injection to monitor your liver and kidney function.
Q3.
Can Posiact 100mg Injection cause skin problems?
Skin problems include a skin rash, dry skin, and itching. This usually goes back to normal when your treatment finishes.
Q4.
Should I use contraception even after the treatment with Posiact 100mg Injection?
Yes, contraception is mandatory during and after treatment with Posiact 100mg Injection for at least six months.
Fact Box of Posiact 100mg Injection
| Molecule name: Etoposide | Pharmacological class: Anti-cancer |
| Therapeutic class: Alkaloids-cytotoxic agents | Indications: 1. Small-cell lung cancer 2. Acute myeloid leukemia (blood cancer) 3. Hodgkin’s lymphoma and non-Hodgkin's lymphoma 4. Ovarian cancer 5. Testicular cancer |
References
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1714 -1715.
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 866.
- Neon Healthcare Limited, Electronic medicines compendium (emc), [ Revised on Sept 2022] [ Accessed on 29th - Mar- 2023 ], pil.10533.pdf (medicines.org.uk)
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details
Written By
Dr. Vijayalakshmi N.
BDS
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:29 AM (IST)
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