Pregnin Retard 40mg Capsule is used in the treatment of the following:

• Peripheral vascular disease improves blood circulation by relaxing blood vessels.
• Preterm labour relaxes uterine muscles and helps prevent premature contractions.
• Raynaud's disease and other circulatory issues to alleviate symptoms and improve blood flow.

Pregnin Retard 40mg Capsule works by blocking alpha-adrenergic receptors, which causes relaxation of the smooth muscle in blood vessels. This leads to vasodilation, improving blood flow and reducing arterial resistance. In the uterus, it also relaxes smooth muscle, helping to prevent premature contractions.

It is important to inform your healthcare professional about all the medications you are taking, including prescription drugs, over-the-counter medications, nutritional supplements, and herbal products. Some medications may interact with Pregnin Retard 40mg Capsule, potentially affecting their effectiveness or causing side effects.

• Keep out of reach of children and pets.
• Store in the original packaging to protect from moisture.
• Avoid direct sunlight
• Store Pregnin Retard 40mg Capsule at a temperature not exceeding 25°C.

Pregnin Retard 40mg Capsule is typically taken orally, depending on the prescribed dosage. The tablet should not be crushed, chewed, or broken, while the capsule should be swallowed whole. For the appropriate dosage and frequency, it is important to consult your healthcare provider, as the exact dosage may differ based on your specific condition and response to treatment.

Side effects are unwanted symptoms caused by medicines. Although all drugs can cause side effects, not everyone experiences them.

Common side effects of Pregnin Retard 40mg Capsule are

• Tachycardia
• Rashes
• Transient flushing
• Gastrointestinal disturbances
• Hypotension

Serious side effects of Pregnin Retard 40mg Capsule are:

• Shortness of breath
• Fetal tachycardia (following intravenous administration in preterm labour)
• Maternal pulmonary edema
• Rapid or irregular heartbeat
• Chest pain
• Fainting or lightheadedness
• Severe allergic reactions (rash, itching, swelling, difficulty breathing)

Follow your healthcare provider's instructions on how to take Pregnin Retard 40mg Capsule. Do not crush, chew, or break the tablet or capsule. Watch for side effects like dizziness, flushing, or chest pain, and report them immediately. If you're pregnant, especially in preterm labour, ensure close monitoring during treatment. Always consult your doctor before adjusting or stopping your medication.

1. National Center for Biotechnology Information (2025). PubChem Compound Summary for CID 11779629, Isoxsuprine. Retrieved February 22, 2025 from https://pubchem.ncbi.nlm.nih.gov/compound/Isoxsuprine.

2. aju PB. Effectiveness and Safety of Isoxsuprine Hydrochloride as Tocolytic Agent in Arresting Active/Threatened Preterm Labor and Its Role in Maintenance Tocolysis: A Prospective, Open-Label Study. https://pubmed.ncbi.nlm.nih.gov/31550735/

3. Alavi A, Rajaee M, Amirian M, Mahboobi H, Jahanshahi KA, Faghihi A. Effect of Maintenance Therapy with Isoxsuprine in the Prevention of Preterm Labor: Randomized controlled trial. https://pmc.ncbi.nlm.nih.gov/articles/PMC4578532/