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Pylokit Tablet
Last updated on 31 Mar 2026 | 09:31 AM (IST)
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Pylokit Tablet is a prescription medicine used to treat Helicobacter pylori (H. pylori) infections in the stomach, which can cause ulcers and gastritis. It contains a combination of pantoprazole (proton pump inhibitor), clarithromycin, and amoxicillin (antibiotics) that work together to reduce stomach acid and eliminate the infection. Pylokit Tablet should be taken exactly as prescribed by a healthcare professional for safe and effective treatment.
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Introduction to Pylokit Tablet
Pylokit tablet contains an active component called Clarithromycin, Lansoprazole and Tinidazole. It is a medicine used to treat peptic ulcer disease (PUD) caused by Helicobacter pylori infection (H. pylori). It is also used to treat gastritis caused by H. pylori infection. Peptic ulcer disease (PUD) is when sores, or ulcers, form in the stomach lining or duodenum (the first part of the small intestine). Gastritis is inflammation of the stomach lining. This medication reduces the risk of complications, such as bleeding and perforation, improving quality of life.
Pylokit tablet should not be taken by people allergic to any ingredients. It is not recommended in people with active liver disease, active heart rhythm problems, pregnancy, or breastfeeding. It should also be used cautiously in people with kidney disease, low magnesium levels, low bone mineral density, tachycardia, or long QT syndrome. It is generally safe for use in older adults. However, older adults may be more likely to experience side effects like diarrhea, nausea, and vomiting. Before starting treatment, talking to your doctor about the risks and benefits of taking this medication is important. Pylokit tablet is not recommended for use in children under 18.
Uses of Pylokit Tablet
- Peptic ulcer disease (PUD) caused by H. pylori infection
- Gastritis caused by H. pylori infection
Therapeutic Effects of Pylokit Tablet
Pylokit tablet works by blocking the production of stomach acid and killing H. pylori bacteria, which helps to heal the ulcer and prevent it from coming back.
Interaction of Pylokit Tablet with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Pylokit tablet, reducing effectiveness by causing undesirable side effects.
More Information about Pylokit Tablet
- Store at room temperature, between 15-25°C
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Pylokit Tablet
Pylokit tablet is administered orally, meaning that it is taken by mouth. The choice of administration route may depend on the situation providing the medication.
Safety Advice for Pylokit Tablet
Breast Feeding
The amount of Pylokit tablet should not be taken while breastfeeding. There is a risk that it could pass into breast milk and harm the baby.
Alcohol
It is not safe to drink alcohol while taking Pylokit tablet. Alcohol can increase the risk of side effects, such as nausea, vomiting, and diarrhea.
Liver
Pylokit tablet can cause liver damage in some people. If you have liver disease, consult your doctor about the risks and benefits of taking this medication.
Lungs
If you have any lung disease, it is advisable to consult your healthcare provider before taking Pylokit tablet.
Driving
Pylokit tablet is unsafe to take while driving as it can cause drowsiness in some people.
Pregnancy
Pylokit tablet is unsafe during pregnancy. There is a risk that it could harm the developing baby. If you are pregnant or planning to become pregnant, talk to your doctor about other treatment options
Side Effects of Pylokit Tablet
Pylokit tablet causes some side effects like all medications, although not everyone will experience them.
Serious:
- Allergic reactions
- Liver damage
- Heart rhythm problems
- QT prolongation
Common:
- Nausea
- Vomiting
- Abdominal pain
- Headache
- Fatigue
- Taste disturbance
- Metallic taste
- Changes in liver function tests
Word of Advice
Be careful if you are taking any other medications that can interact with Pylokit tablet. If you have any underlying medical conditions, such as kidney disease, liver disease, or heart disease, talk to your doctor before taking this medication. This includes antibiotics, antifungals, heart medications, and blood thinners. If you experience any unusual side effects while taking this medication, stop taking the medication and talk to your doctor immediately. Do not take more or less medication than prescribed or longer than prescribed.
FAQs about Pylokit Tablet
Q1.
How long does it take for Pylokit tablet to start working?
Pylokit tablet usually starts working within a few days of taking it. However, it may take up to two weeks to see the full effects of the medication.
Q2.
How long should I take Pylokit tablet?
The length of treatment with Pylokit tablet will vary depending on your individual condition. Your doctor will tell you how long to take this medication.
Q3.
Can I take Pylokit tablet with food?
Pylokit tablet can be taken with or without food. However, if you experience stomach upset, you may want to take this medication with food.
Q4.
What are the side effects of Pylokit tablet?
The most common side effects of Pylokit tablet are diarrhea, nausea, vomiting, abdominal pain, headache, fatigue, taste disturbance, metallic taste, and changes in liver function tests. Most side effects are mild and go away on their own. However, if you experience any serious side effects, stop taking this medication and seek medical attention immediately.
Q5.
Do I need to take any special precautions while taking Pylokit tablet?
If you have any underlying medical conditions, such as kidney disease, liver disease, or heart disease, talk to your doctor before taking Pylokit tablet. It may affect your condition and require a dosage adjustment.
Q6.
What if I miss a dose of Pylokit tablet?
If you miss a Pylokit tablet dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take your next dose as scheduled. Do not take two doses of this medication at once.
Fact Box of Pylokit Tablet
Molecule name: Clarithromycin, Lansoprazole, Tinidazole | Therapeutic class: Gastrointestinal agents |
Pharmacological class: 1. Lansoprazole: Proton pump inhibitor (PPI) 2. Clarithromycin: Macrolide antibiotic 3. Tinidazole: Nitroimidazole antibiotic | Indications: 1. Peptic ulcer disease (PUD) caused by H. pylori infection 2. Gastritis caused by H. pylori infection |
References
- I.D. Penman, C.W. Lees, Alimentary tract and pancreatic disease, Davidson’s Principles & Practice of Medicine, 22nd Edition, 2014, 837-920.
- Ciplamed, [Revised on 25th Jun 2020] [Accessed on 28th Sept 2023], https://www.ciplamed.com/content/pylokit-kit
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details
Written By
Dr. Bhairavi S
Pharm. D
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:31 AM (IST)
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