All Substitutes


Loading...

Disclaimer

Want to know more?
Read Our Editorial Policy

Did you find this information helpful?

    
RAFINLAR 50MG CAPSULE_1
RAFINLAR 50MG CAPSULE_2
RAFINLAR 50MG CAPSULE_3
RAFINLAR 50MG CAPSULE_1
3% Off

Rafinlar 50mg Capsule

Prescription Required

Salt Composition : Dabrafenib

Manufacturer : NOVARTIS INDIA LTD

Origin of Medicine : Switzerland

MRP: 28300
Price :27451
You Save :849 (3%)

28 Capsule(s) In A Bottle


Patient Assistance Programs
Know About PAP

Get financial assistance directly from pharma companies and cover your cost of medicines or get free medicines for the eligible patient with patient assistance programs (PAP). We provide proper guidance assistance to patients getting enrolled in the patient assistance program.

Introduction to Rafinlar 50mg Capsule

Rafinlar 50mg Capsule contains an active molecule named Dabrafenib. It is used to treat skin cancer called melanoma which cannot be removed by surgery or has spread to other body parts. Also prevents melanoma from returning after being removed from surgery. This medication is used to treat a kind of lung cancer called non-small cell lung cancer (NSCLC). It is only used to treat NSCLC and melanomas with abnormal BRAF genes.

In cancer, cancer cells multiply uncontrolled and abnormally. Talk to your physician if you have any liver problems, kidney problems, heart problems, eye problems, breathing problems, gastrointestinal disorders, or have had a different type of cancer before taking this medication. It is not recommended for adolescents and children under the age of 18. Rafinlar 50mg Capsule may impair fertility. Before starting the treatment, talk to your physician about options to improve your chances of having children.


Uses of Rafinlar 50mg Capsule

 Rafinlar 50mg Capsule used in the treatment of 

  • Melanoma
  • Non-small cell lung cancer

Therapeutic Effects of Rafinlar 50mg Capsule

The therapeutic effect of Rafinlar 50mg Capsule is inhibiting the BRAF protein, which plays a crucial role in the signaling pathway that leads to uncontrolled cell growth in cancer cells with the BRAF mutation. By blocking the activity of the BRAF protein, this medication can slow down or stop the growth and spread of cancer cells, leading to the shrinkage of tumors and improving overall health.


Interaction of Rafinlar 50mg Capsule with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Rafinlar 50mg Capsule and reduce effectiveness by causing undesirable side effects.


More Information about Rafinlar 50mg Capsule

  • Rafinlar 50mg Capsule should be stored at room temperature, between 20°C to 25°C (68°F to 77°F).
  • Protected from light.
  • Keep it in its original packaging until it is ready to be used.
  • Keep reaching out of the reach of children and pets.
  • It should be disposed of properly.

How to consume Rafinlar 50mg Capsule

Rafinlar 50mg Capsule is usually taken orally, in the form of a capsule, once or twice a day, with or without food. The dose and frequency depend on several factors, such as the individual's age, weight, overall health, and the type and stage of the cancer being treated. It should be swallowed whole with a full glass of water and not opened, crushed, or chewed. If a dose is missed, it should be taken as soon as possible unless it's almost time for the next scheduled dose, in which case the missed dose should be skipped, and the regular dosing schedule resumed. Do not double the dose to make up for missed doses.


Safety Advices for Rafinlar 50mg Capsule

Image Not Available  

Pregnancy

  

Rafinlar 50mg Capsule is unsafe during pregnancy as it can cause fetal harm. It is s recommended to avoid this medication during pregnancy.

Image Not Available  

Breast Feeding

  

You need to talk to your doctor if breastfeeding before taking Rafinlar 50mg Capsule. It may cause harm to the baby.

Image Not Available  

Lungs

  

Rafinlar 50mg Capsule can cause side effects that affect the lungs, such as cough, shortness of breath, and pneumonitis (inflammation of the lung tissue). In rare cases, it can also cause interstitial lung disease (ILD), a serious and potentially life-threatening condition.

Image Not Available  

Liver

  

Rafinlar 50mg Capsule can affect liver function, and in rare cases, it can cause liver damage, including hepatotoxicity and liver failure. Therefore, it's important to inform your healthcare professional if you have any history of liver problems, such as hepatitis or cirrhosis, before starting treatment.

Image Not Available  

Alcohol

  

It is recommended to avoid consuming alcohol while taking Rafinlar 50mg Capsule, as alcohol can increase the risk of certain side effects associated with the medication, such as stomach ulcers or gastrointestinal bleeding.

Image Not Available  

Driving

  

Patients receiving Rafinlar 50mg Capsule should be advised to avoid driving or operating machinery if they experience side effects such as fatigue, dizziness, or blurred vision, impairing a patient's ability to drive or operate machinery safely.


Side Effects of Rafinlar 50mg Capsule

Rafinlar 50mg Capsule can cause side effects like all medications, although not everyone who takes it will experience them. 

Serious:

  • New or worsening skin lesions or changes in skin color or texture
  • Severe or persistent abdominal pain
  • Signs of liver damage, such as yellowing of the skin or eyes, dark urine, or persistent nausea and vomiting
  • Chest pain or heart palpitations
  • Bleeding or bruising easily
  • Signs of an allergic reaction, such as rash, itching, swelling, dizziness, or difficulty breathing

Common:

  • Nausea and vomiting
  • Diarrhea or constipation
  • Abdominal pain or discomfort
  • Fatigue or weakness
  • Headache
  • Fever
  • Chills
  • Dizziness or lightheadedness
  • Loss of appetite
  • Dry skin or rash
  • Joint pain or muscle pain
  • Cough or shortness of breath

Word of Advice

If you are receiving Rafinlar 50mg Capsule, it's important to be proactive in managing your treatment and monitoring your symptoms. Keep communication with your healthcare provider and report any concerns or side effects as soon as possible. Avoid getting pregnant and breastfeeding during treatment. Use effective birth control during the treatment and at least 2 weeks after the last dose. Use sun protection to avoid the chances of secondary cancer of the skin. Take steps to care for yourself physically and emotionally during treatment, and seek support from loved ones and professionals as needed. Maintain a healthy and balanced diet during treatment to support your overall health and well-being. Being informed and engaged in your treatment can help ensure the best possible outcomes and manage potential risks or complications.


FAQs

Q 1. Can Rafinlar 50mg Capsule be used to treat other types of cancer besides melanoma?

Rafinlar 50mg Capsule is currently only approved for the treatment of melanoma and has not been approved for other types of cancer. But it can also be used to treat non-small cell lung carcinoma.

Q 2. Can Rafinlar 50mg Capsule be combined with other medications for melanoma treatment?

Rafinlar 50mg Capsule is often used with trametinib for treating melanoma.

Q 3. How long do patients typically take Rafinlar 50mg Capsules?

The Rafinlar 50mg Capsule treatment duration can vary depending on the individual patient and their response to treatment. Some patients may take it for several months, while others may take it for several years.

Q 4. Can Rafinlar 50mg Capsule be taken with food?

Rafinlar 50mg Capsule should be taken at least one hour before or two hours after a meal, as food can affect the absorption of the medication.

Q 5. Can Rafinlar 50mg Capsule cause hair loss?

Hair loss is not a common side effect of Rafinlar 50mg Capsule, but it can occur in some patients. Hair growth becomes normal after discontinuing this medication.

Q 6. Can Rafinlar 50mg Capsule be used in pediatric patients?

Rafinlar 50mg Capsule is not currently approved for pediatric patients, and its safety and effectiveness have not been established in this population.


Fact Box of Rafinlar 50mg Capsule

Molecule name: Dabrafenib

Therapeutic class: Anticancer

Pharmacological class: Kinase Inhibitor

Indications:

1. Melanoma

2. Non-small cell lung cancer


References

  1. Novartis Europharm Limited, Electronic medicines compendium (emc), [Revised on Jan 2021] [ Accessed on 19 Artil, 2023], https://www.medicines.org.uk/emc/files/pil.5190.pdf
  2. GlaxoSmithKline, US Food and Drug Administration, [Revised on Jan 2014] [ Accessed on 19 Artil, 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/202806s002lbl.pdf
  3. Enrico Tiacci et al; Safety and efficacy of the BRAF inhibitor dabrafenib in relapsed or refractory hairy cell leukemia: a pilot phase-2 clinical trial; Leukemia; Published on 17/03/2021; [Accessed on 19 Artil, 2023] https://www.nature.com/articles/s41375-021-01210-8.pdf

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

4000+ products

We maintain strict quality controls on all our partner retailers, so that you always get standard quality products.

Secure Payment

100% secure and trusted payment protection

Easy Return

We have a new and dynamic return window policy for medicines and healthcare items. Refer FAQs section for more details.