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Rhoclone 300mcg Injection
Prescription Required
Salt Composition : Anti Rh D Immunoglobulin
Manufacturer : BHARAT SERUMS & VACCINES LTD
Origin of Medicine : India
1 Vial(s)
Introduction to Rhoclone 300mcg Injection
Rhoclone 300mcg injection contains active components called Anti-Rh(D) immunoglobulin. It is a medication used to prevent Rh(D) hemolytic disease of the newborn (HDN). This condition can occur when an Rh-negative mother carries an Rh-positive baby. It significantly reduces the risk of Rh-negative mothers developing antibodies against Rh(D) antigens, which could otherwise lead to HDN in subsequent pregnancies.
Individuals with a known severe allergy or hypersensitivity to any component of anti-Rh(D) immunoglobulin should not receive the medication. It should not be given to Rh-positive mothers as they already have Rh(D) antigens on their red blood cells and cannot develop Rh antibodies. If a woman is already sensitized to Rh(D) antigens (meaning she has developed Rh antibodies in a previous pregnancy or event), administering this medication will not reverse the sensitization. It is only effective as a preventive measure and should not be given in this situation.
Rhoclone 300mcg injection is generally considered safe for use in elderly individuals, provided they meet the necessary criteria for administration based on their blood type and medical history. It can be administered to children when it is medically necessary to prevent Rh sensitization.
Uses of Rhoclone 300mcg Injection
- Prevention of Rh Sensitization
- Prevention of Rh Hemolytic Disease of the Newborn (HDN)
- Preventing Alloimmunization
Therapeutic Effects of Rhoclone 300mcg Injection
Rhoclone 300mcg injection involves the binding of RhIg antibodies to Rh-positive fetal blood cells that enter the maternal bloodstream during pregnancy or childbirth. By covering the Rh(D) antigens on these fetal blood cells, RhIg prevents the mother's immune system from recognizing them as foreign and producing antibodies against them. This neutralization of Rh-positive fetal blood cells effectively prevents Rh sensitization, ensuring the mother's immune system does not develop antibodies that could lead to hemolytic disease of the newborn (HDN) in subsequent pregnancies.
Interaction of Rhoclone 300mcg Injection with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with rhoclone 300mcg injection , reducing effectiveness by causing undesirable side effects.
More Information about Rhoclone 300mcg Injection
- Store at room temperature from 2-8°C.
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Rhoclone 300mcg Injection
Rhoclone 300mcg injection (RhIg) can be administered through two primary routes: intramuscular (IM) injection and intravenous (IV) injection. The doctor chooses the administration route based on the patient's needs and preferences.
Safety Advices for Rhoclone 300mcg Injection
Pregnancy
Rhoclone 300mcg injection is commonly administered during pregnancy to prevent Rh sensitization in Rh-negative mothers carrying Rh-positive babies. Always consult a healthcare provider before taking this medication.
Breast Feeding
Rhoclone 300mcg injection is not contraindicated during breastfeeding. It is a blood product, but the components are not known to pass into breast milk in significant amounts. However, healthcare providers should consider individual circumstances.
Lungs
Individuals with respiratory conditions should consult a health care provider before taking rhoclone 300mcg injection.
Liver
Individuals with liver conditions should consult with their healthcare provider before taking rhoclone 300mcg injection.
Alcohol
There is generally no specific interaction between Rhoclone 300mcg injection and alcohol. However, it's essential to consult your healthcare provider's recommendations and avoid excessive alcohol consumption, which can adversely affect health.
Driving
Rhoclone 300mcg injection can cause side effects, such as fatigue and dizziness. These side effects can affect your ability to drive. It is important to talk to your doctor about whether it is safe for you to drive while taking it.
Side Effects of Rhoclone 300mcg Injection
Rhoclone 300mcg injection causes some side effects like all medications, although not everyone will experience them.
Serious
- Allergic reactions
- Blood Clots (thromboembolism)
- Kidney issues
- Infections
Common
- Local reactions
- Low-grade fever
Word of Advice
When using rhoclone 300mcg injection, healthcare providers should exercise precautions such as confirming the patient's Rh blood type, monitoring for allergic reactions (especially in those with known allergies), assessing clotting risk, closely observing patients with kidney issues, educating about infection transmission risks, considering vaccination timing, evaluating safety during pregnancy and breastfeeding, screening for hepatitis B, administering accurate dosages, being aware of potential drug interactions, ensuring proper storage, monitoring for Rh sensitization efficacy, adjusting dosages for pediatric and geriatric patients, and assessing patients with compromised immune systems or underlying conditions. These precautions help ensure the safe and effective use of this medication for each patient's specific clinical needs while minimizing potential risks.
FAQs
Q 1. Can rhoclone 300mcg injection be administered after a stillbirth or pregnancy termination?
Yes, rhoclone 300mcg injection can be administered after a stillbirth or pregnancy termination, as these events may result in the mixing of maternal and fetal blood, posing a risk of Rh sensitization.
Q 2. What are the common side effects of rhoclone 300mcg injection?
Common side effects of rhoclone 300mcg injection may include mild local reactions at the injection site, such as pain, redness, or swelling. Some individuals may experience a low-grade fever.
Q 3. What is the recommended dosage of rhoclone 300mcg injection?
The dosage of RhIg varies depending on the specific situation and the patient's weight. Healthcare providers follow established guidelines to determine the correct dosage.
Q 4. Can rhoclone 300mcg injection interfere with blood tests or affect typing results?
Rhoclone 300mcg injection administration can temporarily affect blood test results related to Rh typing. Healthcare providers should consider this when interpreting test results and may need to perform additional testing if necessary.
Q 5. Is rhoclone 300mcg injection the same as a vaccine?
No, rhoclone 300mcg injection is not a vaccine. It is a medication that contains antibodies against the Rh(D) antigen and is used to prevent the development of Rh antibodies in Rh-negative individuals exposed to Rh-positive blood.
Q 6. Are there any dietary restrictions or lifestyle changes necessary when receiving rhoclone 300mcg injection?
There are typically no specific dietary restrictions or lifestyle changes required when receiving rhoclone 300mcg injection. Patients should continue their regular routines unless advised otherwise by their healthcare provider.
Fact Box of Rhoclone 300mcg Injection
Molecule name: Anti-Rh(D) immunoglobulin
| Therapeutic class: Immunomodulator |
Pharmacological class: Immunoglobulin G (IgG) | Indications: Immune Globulins
|
References
- Athina L. Yoham, Damian Casadesus, [Revised on 27th May 2021] [Accessed on 26 September 2023], https://www.ncbi.nlm.nih.gov/books/NBK557884/
- CSL Behring GmbH, [Revised on Jun 2019] [Accessed on 26 September 2023], https://www.medicines.org.uk/emc/files/pil.6791.pdf
- CSL Behring (NZ) Ltd, [Revised on Jun 2021] [Accessed on 26 September 2023], https://www.medsafe.govt.nz/profs/Datasheet/r/RhDimmunoglobulinVFinj.pdf
Disclaimer
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