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Rpmel 5mg Tablet
Last updated on 31 Mar 2026 | 09:30 AM (IST)
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Introduction to Rpmel 5mg Tablet
Rpmel 5mg tablet contains an active ingredient called Metolazone, which belongs to the group of medicines called thiazide diuretics. It is used to treat fluid retention (edema) associated with heart and kidney conditions by promoting urine flow. It is also used to treat high blood pressure, either alone or in combination with other medications.
Do not use Rpmel 5mg tablet if you are allergic to Metolazone, thiazides, sulfonamides, or any of its ingredients. Do not use this medication if you are unable to urinate, experiencing coma or comatose conditions due to liver cirrhosis, or have severe imbalances of salts or chemicals in your blood. Before start taking medicine, talk to your doctor if you have severe kidney or liver disease, are elderly, have fluid or electrolyte imbalances, or suffer from Addison's disease, diabetes, gout, systemic lupus erythematosus.
Notify your doctor if you have porphyria, high cholesterol, or have a history of penicillin or sulfonamide allergy. Rpmel 5mg tablet contains lactose, so if you have galactose intolerance, total lactase deficiency, or glucose-galactose malabsorption, it is advised to avoid it. Regular monitoring may be necessary for certain conditions. This medicine is not recommended for children under the age of 18, and it should be used cautiously in elderly patients.
Uses of Rpmel 5mg Tablet
- Treats fluid retention (edema) associated with heart and kidney conditions.
- Manage high blood pressure, with or without other medications.
Therapeutic Effects of Rpmel 5mg Tablet
Rpmel 5mg tablet works by increasing the flow of urine and promoting the removal of excess fluid from the body. It achieves this by blocking the reabsorption of sodium and water in the kidneys, which helps to reduce fluid retention (edema). Additionally, this medicine also helps to widen the blood vessels, leading to a decrease in blood pressure, making it effective for managing hypertension.
Interaction of Rpmel 5mg Tablet with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Rpmel 5mg tablet and can cause undesirable side effects.
More Information about Rpmel 5mg Tablet
- Keep out of sight and reach of pets and children.
- Store between 15°C - 30°C.
- Always check the expiry date before consuming it.
How to consume Rpmel 5mg Tablet
Take the Rpmel 5mg tablet as your physician advises. Do not take more or less of the medication than your doctor has instructed. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.
Safety Advice for Rpmel 5mg Tablet
Breast Feeding
It is unsafe to consume Rpmel 5mg tablet during breastfeeding. So, before starting the treatment, inform your doctor if you are breastfeeding. Contact your doctor for more information.
Alcohol
Do not consume alcohol while taking Rpmel 5mg tablet because your blood pressure may decrease and result in dizziness, debility, and fatigue. Please speak with your physician for more information.
Liver
Rpmel 5mg tablet should be used cautiously in patients with liver conditions. Before starting the treatment, inform your physician about pre-existing liver conditions.
Lungs
It is unknown whether Rpmel 5mg tablet is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Driving
Do not drive or operate machinery if you experience side effects like dizziness and fatigue from Rpmel 5mg tablet, as it may affect your ability to do so safely.
Pregnancy
It is unsafe to consume Rpmel 5mg tablet during pregnancy. Before starting the treatment, inform your doctor if you are pregnant or planning to get pregnant or think you may be pregnant
Side Effects of Rpmel 5mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Common
- Nausea
- Muscle pain and cramps
- Headache, dizziness, and fatigue
- Low blood pressure and dizziness on standing (orthostatic hypotension)
- Low levels of potassium, sodium, magnesium, and chloride in the blood
- High levels of uric acid, urea, creatinine, and sugar in the blood
- Glucose in the urine
- Vomiting
- Constipation
- Diarrhea
Word of Advice
Patients with liver, and kidney conditions should take Rpmel 5mg tablet cautiously and should inform the doctor about all the underlying medical conditions. Do not stop the medicine until your doctor advises. Do not double-dose the medicine to make up for a forgotten dose. Notify your doctor if you experience any serious side effects. Your medical professional will inform you if you need any dose adjustments. Contact your doctor for more information.
FAQs about Rpmel 5mg Tablet
Q1.
Can I use Rpmel 5mg tablet if I’m pregnant?
Do not consume Rpmel 5mg tablet during pregnancy. Notify your doctor if you are pregnant or planning to get pregnant, or think you may be pregnant.
Q2.
Who should not take Rpmel 5mg tablet?
Rpmel 5mg tablet should not be taken by people who are allergic to it. It should also not be taken by people who have severe kidney disease, liver disease, or hypokalemia (low potassium levels). Rpmel 5mg tablet should be used with caution in people who have diabetes, gout, or a history of kidney stones.
Q3.
Can I use Rpmel 5mg tablet with other medications?
Before using this medicine, it is essential to consult your doctor, as they can interact with various other medications. Getting suggestions from your doctor will help ensure the safe and appropriate use of Rpmel 5mg tablet with your current medication regimen.
Q4.
What are the side effects of Rpmel 5mg tablet?
The most common side effects of Rpmel 5mg tablet are dizziness, lightheadedness, and fatigue. These side effects are usually mild and go away on their own. Other side effects, such as low potassium levels, high blood sugar levels, and gout, can be more serious. If you experience any side effects that are bothersome or do not go away, talk to your doctor.
Q5.
Is that okay to consume alcohol while taking Rpmel 5mg tablet?
Do not consume alcohol while taking Rpmel 5mg tablet because your blood pressure may decrease and result in dizziness, debility, and fatigue.
Fact Box of Rpmel 5mg Tablet
| Molecule Name: Metolazone | Therapeutic class: Cardiology |
| Pharmacological class: Thiazide diuretics | Indications: 1. Treats fluid retention (edema) associated with heart and kidney conditions. 2. Manage high blood pressure with or without other medications. |
References
- Renascience Pharma Limited, Electronic medicines compendium (emc), [Revised on May 2021] [ Accessed on 25th July 2023], Xaqua 5mg UK leaflet Mock Up 4.ai (medicines.org.uk)
- Lannett Company, Inc, US Food and Drug Administration, [Revised on May 2019] [ Accessed on 25th July 2023], label (fda.gov)
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Regulation of renal function and vascular volume, 12th edition, 2011, 688.
- KD Tripathi, Essentials of Medical Pharmacology, Diuretics, 7th edition, 2013, 583.
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details
Written By
Aswini Priya Velmurugan
PG in Biotechnology
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:30 AM (IST)
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