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Safimao 50mg Tablet
Last updated on 31 Mar 2026 | 09:29 AM (IST)
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Introduction
Safimao 50mg Tablet contains active components called Safinamide. This medication is used to treat Parkinson's disease. It helps reduce the symptoms of Parkinson's disease(a neurodegenerative disorder that affects movement), such as tremors, stiffness, and slowness of movement. Individuals who have had a hypersensitivity or allergic reaction to Safimao 50mg Tablet or any of its components should avoid using this medication. Avoid using it concurrently or within 14 days of discontinuing other MAO inhibitors, as it can lead to potentially serious drug interactions and increase the risk of serotonin syndrome. It might not be suitable for individuals with pheochromocytoma due to its potential to increase blood pressure and stimulate the release of certain hormones. Individuals with kidney impairment should use Safimao 50mg Tablet with caution. The safety and efficacy of Safimao 50mg Tablet in children have not been established, so it is not typically recommended for children. This mediation can be used in older adults, but caution may be needed due to age-related changes in drug metabolism and the potential for other health issues.
Uses
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Parkinson's disease treatment
How Safimao 50mg Tablet Works
Safimao 50mg Tablet works by increasing levels of dopamine in the brain, helping to manage symptoms like tremors, stiffness, and slowness of movement associated with Parkinson's disease.
Interaction of Safimao 50mg Tablet with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with the Safimao 50mg Tablet, reducing effectiveness by causing undesirable side effects.
Storage Conditions
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Stored at controlled room temperature between 20°C to 25°C
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Keep away from moisture, heat, and light.
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It should not be frozen.
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Keep away from children and pets.
How to take Safimao 50mg Tablet
Safimao 50mg Tablet is administered orally, meaning you take it by mouth. The recommended dosage may be adjusted by a healthcare professional as needed.
Safety Advices
Breast Feeding
There is limited data on whether Safimao 50mg Tablet passes into breast milk. Consult your doctor for advice before taking this medication if you are a breastfeeding mother.
Alcohol
Drinking alcohol while taking Safimao 50mg Tablet may increase the risk of certain side effects, such as dizziness or drowsiness, so it is not safe to take with alcohol.
Liver
If you have a liver condition or are concerned about the safety of the Safimao 50mg Tablet. In that case, it is recommended that you consult your healthcare provider for personalized advice.
Lungs
Consult your health care provider before taking Safimao 50mg Tablet if you have lung disease.
Driving
Safimao 50mg Tablet might cause dizziness, drowsiness, or other side effects that could impair one's ability to drive or operate machinery. Consult your healthcare provider before taking it after driving.
Pregnancy
Talk to your doctor before taking Safimao 50mg Tablet if you are pregnant or trying to become pregnant, as its safety during pregnancy has not been fully established.
Side Effects
Safimao 50mg Tablet causes side effects like all medications, although not everyone will experience them.
Serious:
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Allergic reactions
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Hallucinations or psychiatric symptoms
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Serotonin syndrome
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Changes in liver function
Common:
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Nausea
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Insomnia
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Dizziness
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Headache
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Uncontrolled movements
Expert tips
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Inform your doctor about all medications, supplements, or herbal products you are taking to avoid potential interactions.
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Use Safimao 50mg Tablet with caution alongside other medicines that increase serotonin levels, as this may cause serotonin syndrome.
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Watch for symptoms like confusion, hallucinations, rapid heart rate, or high blood pressure, and report them to your doctor immediately.
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Regularly monitor your blood pressure, especially when starting treatment or adjusting the dose, and inform your doctor of any unusual changes in mental health.
FAQs
Q1.
Can Safimao 50mg Tablet be used alone to treat Parkinson's?
Safimao 50mg Tablet is often used in combination with other Parkinson's medications, especially levodopa/carbidopa, to enhance their effects and manage motor fluctuations.
Q2.
What are the common side effects of Safimao 50mg Tablet?
Common side effects of the Safimao 50mg Tablet may include nausea, insomnia, dizziness, headaches, and uncontrolled movements.
Q3.
What should I do if I miss a dose of Safimao 50mg Tablet?
If you miss a dose of Safimao 50mg Tablet, take it as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.
Q4.
Can Safimao 50mg Tablet be stopped suddenly?
It is important not to stop taking Safimao 50mg Tablet abruptly without consulting your healthcare provider. They can provide guidance on tapering off the medication if necessary.
Q5.
Are there specific dietary restrictions while taking Safimao 50mg Tablet?
Safimao 50mg Tablet doesn't typically have specific dietary restrictions. However, discussing dietary considerations with your doctor, especially concerning tyramine-rich foods if taking other MAO inhibitors is advisable.
Q6.
How often should I have check-ups while on a Safimao 50mg Tablet?
The frequency of check-ups varies based on individual needs and responses to the Safimao 50mg Tablet. Your doctor will determine the appropriate schedule for monitoring your condition while taking this medication.
Expert tips
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Molecule name: |
Safinamide |
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Therapeutic class: |
Antiparkinsonian agent |
|
Pharmacological class: |
Monoamine oxidase B (MAO-B) inhibitors |
|
Indications: |
Parkinson's disease treatment |
References
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U.S FDA (Food and Drug Safety Administration), [ Last Revised 21st March 2017], [Accessed on 29th Dec 2023], https://www.fda.gov/news-events/press-announcements/fda-approves-drug-treat-parkinsons-disease
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Baker DE, Kim AP. Formulary Drug Review: Safimao 50mg Tablet. Hosp Pharm.[Published on 2017 September] [Accessed on 29th Dec 2023]
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details

Written By
P. Thirumal Reddy
B. Pharm

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:29 AM (IST)

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