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Salphaz 500mg Tablet
Last updated on 26 Sep 2026 | 08:43 AM (IST)
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Salphaz 500 mg Tablet is a prescription medicine used to treat ulcerative colitis, Crohn’s disease, and rheumatoid arthritis. It contains sulfasalazine, which works by reducing inflammation in the intestines and joints, helping relieve symptoms like pain, swelling, and bowel discomfort.
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Introduction to Salphaz 500mg Tablet
Salphaz 500mg Tablet is an antibiotic medication containing the active ingredient Sulphadiazine. This medication is used to treat various bacterial infections such as urinary tract infections, respiratory tract infections, and certain types of pneumonia caused by susceptible bacteria. It mainly inhibits the synthesis of folic acid in bacteria, disrupting their ability to grow and multiply.
Individuals with known allergies to sulfonamides should not use Salphaz 500mg Tablet. Patients with a history of kidney disease should use this drug cautiously, as the drug is primarily excreted through the kidneys. Individuals with kidney issues, including kidney stones, may require special monitoring and dosage adjustments when taking this drug. Your doctor needs to evaluate your kidney function and determine your suitable dose. Adequate hydration is essential to reduce the risk of crystallization of the drug in the urine, which can lead to kidney damage.
Salphaz 500mg Tablet may cause blood disorders, such as agranulocytosis or aplastic anemia. Regular monitoring of blood counts is often recommended during prolonged therapy. This drug is generally avoided in infants under two months of age due to the risk of kernicterus (a type of brain damage) in newborns. This medicine may increase sensitivity to sunlight. Patients are advised to use sunscreen and protective clothing to avoid sunburn. You should not breastfeed while taking this tablet since your newborn is at risk of brain damage. Inform your doctor if you are breastfeeding before taking this medicine. This tablet may harm your unborn baby. Tell your doctor if you are pregnant or planning to get pregnant before taking this medicine.
Uses of Salphaz 500mg Tablet
- Treatment of bacterial infections
Therapeutic Effects of Salphaz 500mg Tablet
Salphaz 500mg Tablet works by blocking the synthesis of folic acid, which is essential for bacterial growth. Without folic acid, bacteria cannot produce important components necessary for their reproduction.
Interaction of Salphaz 500mg Tablet with other drugs
Inform your physician about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Salphaz 500mg Tablet and reduce effectiveness by causing undesirable side effects.
More Information about Salphaz 500mg Tablet
- Store Salphaz 500mg Tablet in a cool, dry and dark place
- Protect from light and moisture.
How to consume Salphaz 500mg Tablet
Take the Salphaz 500mg Tablet as advised by your physician. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.
Safety Advice for Salphaz 500mg Tablet
Breast Feeding
Small amounts of this drug can pass into breast milk. If you plan to breastfeed while taking Salphaz 500mg Tablet, you should consult your doctor.
Alcohol
It is unknown whether consuming alcohol interacts with the Salphaz 500mg Tablet. Please consult your doctor for more advice.
Liver
Salphaz 500mg Tablet should be cautiously administered in patients with severe liver diseases. Dose adjustments are necessary. Inform your doctor if you have liver issues before initiating the therapy.
Lungs
It is unknown whether Salphaz 500mg Tablet is safe for patients with lung problems. Inform your physician if you have lung disease before starting the treatment.
Driving
Salphaz 500mg Tablet may be less likely to impair your ability to drive or operate machinery. Consult your doctor for more advice.
Pregnancy
It's advised not to take Salphaz 500mg Tablet during late pregnancy due to serious side effects on your unborn child. If you are pregnant or planning to become pregnant, it's important to discuss the use of this tablet with your doctor.
Side Effects of Salphaz 500mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Severe allergic reactions
- Severe diarrhea
- Lower back pain, blood in urine, passing urine less than usual
Common
- Nausea
- Loss of appetite
Word of Advice
Tell your doctor immediately about all the medications you have been taking recently, including herbal and supplements, before taking Salphaz 500mg Tablet. If you forget to take this medicine for the entire day, take your usual dose the next day. However, do not double-dose yourself. Throw away medicines that are no longer needed or are out-of-date. Keep medicines away from children and pets. Do not store these medicines in a damp place such as a bathroom, cabinet, or near the kitchen sink.
FAQs about Salphaz 500mg Tablet
Q1.
How is Salphaz 500mg Tablet administered?
Salphaz 500mg Tablet is usually taken orally as tablet or suspension. In some cases, it may also be used topically as a cream or ointment for skin infections or burns.
Q2.
What types of infections can Salphaz 500mg Tablet treat?
Salphaz 500mg Tablet is often used to treat or prevent infections caused by bacteria, including urinary tract infections, burn wound infections, and certain respiratory infections.
Q3.
Is Salphaz 500mg Tablet effective against viral infections?
Salphaz 500mg Tablet is specifically designed to target bacterial infections and is not effective against viral infections such as the flu or common cold.
Q4.
Are there any potential side effects of Salphaz 500mg Tablet?
Salphaz 500mg Tablet may cause side effects. Common side effects include nausea, vomiting, diarrhea, and allergic reactions. It's important to report any severe or persistent side effects to a healthcare professional.
Q5.
What precautions should I take while using Salphaz 500mg Tablet?
It's important to drink plenty of fluids while using Salphaz 500mg Tablet to prevent crystallization in the urinary tract. Avoid prolonged exposure to sunlight as this drug can make your skin more sensitive to UV rays.
Q6.
Are there any drug interactions with Salphaz 500mg Tablet?
Salphaz 500mg Tablet may interact with certain medications, including anticoagulants and oral hypoglycemic agents. It's important to inform your healthcare provider about all the medications you are taking to avoid potential interactions.
Fact Box of Salphaz 500mg Tablet
Molecule name: Sulphadiazine | Therapeutic class: Antibiotic |
Pharmacological class: Sulfonamide derivatives | Indications: Treatment of bacterial infections |
References
- Wockhardt UK Ltd, Electronic medicines compendium (EMC), [Revised on Aug 2015] [Accessed on 9 August 2023], https://www.medicines.org.uk/emc/files/pil.253.pdf
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Sulfonamides, trimethoprim, sulfamethoxazole, quinolones, and agents for urinary tract infections, 12th edition, 2011, 1463 - 1467.
- KD Tripathi, Essentials of Medical Pharmacology, Sulfonamides, cotrimoxazole and quinolones, 7th edition, 2013, 705.
Disclaimer
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Author Details
Written By
Dr. B. Deiva
Pharm D
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 26 Sep 2026 | 08:43 AM (IST)
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