Sevura Inhaler contains the active component Sevoflurane. It is used to produce a complete loss of sensation in the body, including unconsciousness, so that surgical operations or other procedures can be performed. This allows surgery to be carried out without pain or distress.  This medication is used in the hospital environment only and has a quick induction and emergence time. This helps in efficiently managing the anesthesia process. It can be easily adjusted and titrated to maintain the desired level of sedation throughout the procedure. Sevura Inhaler is suitable for many patients, including pediatric and elderly populations. It can be safely used in various surgical procedures and with other anesthetic agents and adjuncts.

Individuals with known hypersensitivity or allergy to Sevura Inhaler or other halogenated ethers should not receive this anesthesia. Like other volatile anesthetics, it can trigger malignant hyperthermia, a rare but potentially life-threatening condition characterized by a severe reaction to certain medications used during general anesthesia. Patients with a personal or family history of MH or suspected susceptibility to MH should avoid Sevura Inhaler. Although it is primarily eliminated through exhalation, caution should be exercised in patients with severe renal impairment. Patients with certain pre-existing cardiac conditions, such as severe cardiovascular disease or unstable angina, may require caution when using this medication.

• Produce unconsciousness for surgical procedures

Sevura Inhaler induces and maintains general anesthesia, providing rapid onset and offset, controllable depth of anesthesia, cardiovascular stability, and low airway irritation, enabling safe and effective surgical procedures.

Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Sevura Inhaler, reducing effectiveness by causing undesirable side effects.

• Stored at controlled room temperature, between 20°C to 25°C (68°F to 77°F).
• Keep away from moisture, heat, and light.
• It should not be frozen.
• Keep away from children and pets.

Sevura Inhaler is administered by inhalation during general anesthesia using a vaporizer. The patient breathes in through a mask or tube, and the anesthesiologist adjusts the concentration for the desired level of anesthesia. After surgery, administration is stopped, and the patient gradually wakes up from anesthesia.

Sevura inhalers cause some side effects like all medications, although not everyone will experience them. 

Serious:

• Allergic reactions
• Malignant hyperthermia (rapid increase in body temperature and muscle rigidity)
• Respiratory depression

Common:

• Nausea and vomiting
• Headache
• Dizziness
• Shivering

Inform your healthcare provider about any pre-existing medical conditions, allergies, or medications you are taking Sevura Inhaler. It is important to understand the potential risks and benefits associated with this anesthesia fully and to ask any questions or address any concerns you may have. Before using it, talk to your physician if you have liver disorders, seizures, heart problems, or allergic conditions. Trust and communicate openly with your healthcare team to ensure safe and effective anesthesia administration.

1. KD Tripathi, Essentials of Medical Pharmacology, General anesthetics, 7th edition, 2013, 381.
2. AbbVie Ltd, Electronic medicines compendium (EMC), [Revised on 2 July 2021] [Accessed on 9th June 2023], https://www.medicines.org.uk/emc/product/833/pil#gref
3. Abbott Laboratories, US Food, and Drug Administration, [Revised on Jan 2003] [Accessed on 9th June 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/020478s016lbl.pdf