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Silotrif M 50mg Tablet
Prescription Required
Salt Composition : Mirabegron,silodosin
Manufacturer : MSN LABORATORIES (INDIA)
Origin of Medicine : India
10 Tablet(s) In A Strip
Introduction to Silotrif M 50mg Tablet
Silotrif M 50mg Tablet combines the active constituents Mirabegron and Silodosin, offering dual-action therapeutic benefits. Mirabegron belongs to the pharmacological class of beta-3 adrenergic agonists and is primarily indicated for managing overactive bladder symptoms. Silodosin, an alpha-1 adrenergic blocker, is used for treating urinary retention caused by benign prostatic hyperplasia (BPH). Together, these molecules target urinary health, alleviating discomfort caused by urinary disorders.
Silotrif M 50mg Tablet is effective for adults with conditions requiring relaxation of bladder muscles and improved urine flow. While safe for most patients, it is crucial to follow dosage instructions to minimise potential side effects. Contraindications include severe liver or kidney impairments, uncontrolled hypertension, or hypersensitivity to any ingredient. Always consult your doctor for personalised advice.
Uses of Silotrif M 50mg Tablet
- Overactive bladder symptoms such as frequent or urgent urination.
- Urinary retention or difficulty due to benign prostatic hyperplasia (BPH).
- Relief of bladder muscle overactivity in specific medical conditions.
Therapeutic Effects of Silotrif M 50mg Tablet
The therapeutic action of Silotrif M 50mg Tablet stems from its dual mechanisms. Mirabegron works by relaxing bladder muscles, enabling the bladder to store more urine and reducing urgency and frequency. Silodosin eases the muscles of the prostate and bladder neck, enhancing urine flow in patients with BPH.
These actions address underlying dysfunctions in urinary pathways, providing symptom relief and improving quality of life.
Interaction of Silotrif M 50mg Tablet with other drugs
Interactions may occur if Silotrif M 50mg Tablet is taken with specific medications. Avoid combining it with:
- Antihypertensive drugs: May intensify blood pressure-lowering effects.
- Ketoconazole or other strong CYP3A4 inhibitors: Increases Silodosin’s plasma concentration.
- Digoxin: Mirabegron can raise its levels, necessitating dose adjustments.
- Warfarin: Monitor for altered anticoagulant effects.
- Other adrenergic agonists or blockers: May result in amplified or diminished effects.
Always inform your doctor about any medication you are taking to ensure safety.
More Information about Silotrif M 50mg Tablet
- Store at room temperature (15°C–30°C) away from direct sunlight and moisture.
- Take the missed dose as soon as remembered unless close to the next dose. Avoid doubling doses.
- Seek immediate medical attention if overdosed, as it may lead to severe symptoms such as high blood pressure or dizziness.
How to consume Silotrif M 50mg Tablet
- Dosage form: Tablet.
- Recommended dose: As directed by your doctor, typically one tablet daily.
- Administration: Take orally with or without food. Swallow whole; do not crush or chew.
Safety Advices for Silotrif M 50mg Tablet
Pregnancy
Limited data on use during pregnancy. Not recommended unless benefits outweigh risks.
Breast Feeding
Safety during breastfeeding is not established. Avoid use or consult a healthcare provider.
Lungs
Patients with severe respiratory conditions should exercise caution due to potential side effects.
Liver
Avoid in severe liver impairment as it may increase adverse effects.
Alcohol
Avoid alcohol consumption to prevent enhanced dizziness or drowsiness.
Driving
May cause dizziness or blurred vision; avoid driving if affected.
Side Effects of Silotrif M 50mg Tablet
Common Side Effects
- Dizziness
- Headache
- Dry mouth
- Nausea
- Fatigue
Serious Side Effects
- Severe allergic reactions (rash, swelling, difficulty breathing)
- Elevated blood pressure
- Urinary retention
Word of Advice
Use Silotrif M 50mg Tablet under strict medical supervision to avoid complications. Regular monitoring of blood pressure and liver function is advised. If you experience persistent side effects, contact your doctor immediately.
FAQs
Q 1. What is Silotrif M 50mg Tablet used for?
Silotrif M 50mg Tablet is used to treat overactive bladder symptoms and urinary retention caused by benign prostatic hyperplasia.
Q 2. Can I use Silotrif M 50mg Tablet for both BPH and overactive bladder?
Yes, this combination is specifically designed to manage both conditions effectively.
Q 3. Is Silotrif M 50mg Tablet safe for elderly patients?
Yes, but it should be used cautiously, especially in those with liver or kidney conditions.
Q 4. Can I take Silotrif M 50mg Tablet with blood pressure medication?
Silotrif M 50mg Tablet may interact with antihypertensives; consult your doctor for appropriate guidance.
Q 5. How soon can I see results with Silotrif M 50mg Tablet?
Most patients notice symptom improvement within a few weeks of consistent use.
Fact Box of Silotrif M 50mg Tablet
| Molecule name: Mirabegron, Silodosin | Pharmacological class: Beta-3 adrenergic agonist, Alpha-1 adrenergic blocker
|
| Therapeutic class: Urinary disorder medications | Indications: 1. Overactive bladder 2. Benign prostatic hyperplasia |
References
- https://jptcp.com/index.php/jptcp/article/view/4523
- https://pubmed.ncbi.nlm.nih.gov/39345311/
- https://cdsco.gov.in/opencms/resources/UploadCDSCOWeb/2018/UploadCTApprovals/14.Mirabegron%20(As%20extended%20release)%20+%20Silodosin%20film%20coated%20bilayered%20tablets%20(Phase%20III).pdf
- https://link.springer.com/article/10.1007/s11255-023-03880-y
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