Soliris 300mg Injection contains the active ingredient Eculizumab. it is a medication that works by inhibiting the complement protein C5 in the immune system. It is primarily used to treat rare blood disorders such as paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), and generalised myasthenia gravis (gMG). The benefits of this medication include preventing the destruction of red blood cells, reducing the risk of blood clots, improving kidney function, and helping manage muscle weakness associated with autoimmune conditions.

Soliris Injection is also prescribed in conditions where uncontrolled complement activation can cause organ damage. The complement system is a part of the immune system that normally protects the body from infections, but can attack healthy cells when overactive.

The Soliris Injection price varies depending on dosage and pack size. Patients should consult their doctor or pharmacist for the exact cost. Always purchase from verified pharmacies to ensure safety, authenticity, and proper storage of the medication.

Soliris 300mg Injection is approved for the following conditions:

• Paroxysmal Nocturnal Hemoglobinuria (PNH): Prevents destruction of red blood cells and reduces anaemia and risk of blood clots.

• Atypical Hemolytic Uremic Syndrome (aHUS): Helps protect kidneys and prevents organ damage caused by uncontrolled complement activation.

• Generalised Myasthenia Gravis (gMG): Reduces muscle weakness and improves daily functioning in patients with antibodies against acetylcholine receptors.

• Prevention of Complement-Mediated Organ Damage: Used in conditions where overactivation of the complement system can harm organs.

• Other Rare Complement-Mediated Disorders: May be prescribed for other conditions as determined by a physician.

Soliris 300mg Injection is a medicine that works by blocking a specific protein called C5 in the immune system. Normally, this protein helps the body fight infections. However, in certain diseases, it can target healthy red blood cells and organs, leading to severe complications.

In conditions like paroxysmal nocturnal hemoglobinuria (PNH), Soliris 300mg Injection prevents the destruction of red blood cells, reducing anaemia and the risk of blood clots. In atypical hemolytic uremic syndrome (aHUS), it protects the kidneys and other organs from damage caused by an overactive immune system.

For people with generalised myasthenia gravis (gMG), Soliris 300mg Injection reduces the immune system’s attack on nerves and muscles, helping improve muscle strength and daily functioning.

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter drugs, nutritional or vitamin supplements, and herbal products. Some medicines may interact with Soliris 300mg Injection and affect its effectiveness or increase the risk of side effects.

Particularly, medications that affect the immune system or increase the risk of infections may require close monitoring while using Soliris 300mg Injection. Always consult your physician before starting or stopping any medicine during your treatment.

• Store Soliris 300mg Injection at room temperature between 68°F to 77°F (20°C to 25°C).

• Keep the medicine in its original package to protect it from light.

• Do not freeze the medicine. Keep it away from heat, moisture, and direct sunlight.

• Keep it out of reach of children and pets.

• Do not shake the vial or prefilled syringe. Handle gently before use.

Soliris 300mg Injection is given as an intravenous (IV) infusion by a healthcare professional, and your doctor will decide the exact dose and schedule based on your condition. It is important not to self-administer this medication at home unless specifically instructed. Follow all instructions carefully regarding the dose, timing, and frequency, and do not skip doses or change the schedule without consulting your doctor. If you experience any side effects or unusual reactions during or after the infusion, inform your healthcare provider immediately. Regular blood tests and check-ups may be needed to monitor your response and ensure the medicine is working safely and effectively.

Like all medications, Soliris 300mg Injection can cause side effects, although not everyone who takes it will experience them.

Serious

• Severe infections (due to immune system suppression)

• Infusion-related reactions (fever, chills, low blood pressure, difficulty breathing)

• Blood clots (deep vein thrombosis or pulmonary embolism)

• Liver problems (jaundice, dark urine, abdominal pain, nausea, vomiting)

• Allergic reactions (rash, swelling, severe itching, anaphylaxis)

Common

• Headache

• Fatigue

• Nausea

• Diarrhea

• Fever or mild chills

• Dizziness

• Cough or mild shortness of breath

• Skin rash or redness at the injection site.

• Follow your doctor’s instructions carefully regarding dose and schedule.

• Report any side effects or unusual health changes immediately.

• Inform your doctor if you have liver, lung, or kidney problems.

• Women who could become pregnant should use effective birth control during and after treatment.

• Maintain a healthy diet and stay well-hydrated.

• Use sun protection when outdoors, as skin may be sensitive during treatment.