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Somastin 3000mcg Injection
Last updated on 31 Mar 2026 | 09:29 AM (IST)
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Introduction to Somastin 3000mcg Injection
Somatostatin 3000mcg Injection contains the active substance Somatostatin. It is a synthetic compound of octreotide, a substance naturally found in the human body that inhibits the effects of certain hormones, such as growth hormones. It is used to reduce the amount of growth hormone produced by people with acromegaly (a condition in which the body produces too much growth hormone, causing enlargement of the hands, feet, and facial features, joint pain, and other symptoms) who cannot be treated with surgery, radiation, or another medication.
It is also used to control diarrhea and flushing caused by carcinoid tumors (slow-growing tumors that release natural substances that can cause symptoms) and vasoactive intestinal peptide-secreting adenomas (VIP-omas, tumors that form in the pancreas and release natural substances that can cause symptoms). It is used to prevent complications following surgery of the pancreas gland. It is also indicated to stop bleeding and to protect from re-bleeding from ruptured gastro-esophageal varices in patients suffering from chronic liver disease. Somatostatin 3000mcg Injection is used to treat people with pituitary tumors that produce too much thyroid-stimulating hormone (TSH) when other types of treatment (surgery or radiotherapy) are not suitable or have not worked and after radiotherapy, to cover the interim period until the radiotherapy becomes fully effective.
Uses of Somastin 3000mcg Injection
- To treat acromegaly
- Relieve symptoms associated with some tumors of the GI tract
- To prevent complications following surgery of the pancreas gland
- To treat pituitary tumors that produce too much TSH
Therapeutic Effects of Somastin 3000mcg Injection
Somatostatin, a neuropeptide agent, inhibits growth hormone, glucagon, and insulin more effectively than the natural hormone. The drug also reduces growth hormone and IGF-I (somatomedin C) in acromegaly, inhibits gallbladder contractions, reduces bile secretion, and suppresses thyroid stimulating hormone (TSH) secretion.
Interaction of Somastin 3000mcg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications interact with Somatostatin 3000mcg Injection and reduce their effectiveness by causing undesirable side effects.
More Information about Somastin 3000mcg Injection
- Store the Somatostatin 3000mcg Injection in the refrigerator at 2°C to 8°C
- Do not freeze
How to consume Somastin 3000mcg Injection
Always use this medicine as exactly prescribed by your doctor. Depending on the condition being treated, an infusion of Somatostatin is given by either subcutaneous (under the skin) injection, intramuscularly (into the muscle of the buttocks), or intravenous (into a vein). If you are prescribed a subcutaneous injection, your doctor or other healthcare professional will explain how to inject the medicine under the skin.
Safety Advice for Somastin 3000mcg Injection
Breast Feeding
Breastfeeding is not recommended in patients taking Somatostatin 3000mcg Injection because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.
Alcohol
It is unsafe to drink alcohol while you take Somatostatin 3000mcg Injection because it may cause damage to your liver.
Liver
It is unknown whether Somatostatin 3000mcg Injection can be used in patients with liver issues. Consult your doctor if you have any lung diseases before starting the treatment.
Lungs
It is unknown whether Somatostatin 3000mcg Injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Driving
Somatostatin 3000mcg Injection does not alter your ability to drive and operate heavy machinery. If you feel dizzy, consult the doctor before driving or using machines.
Pregnancy
Somatostatin 3000mcg Injection will only be given during pregnancy if needed. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment. Use effective contraception during the treatment.
Side Effects of Somastin 3000mcg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Increased heart rate
- Changes in heart rhythm
- Increased or decreased blood sugar levels
- Changes in thyroid levels
- Vitamin B12 deficiency
- Gall stones
Common
- Diarrhea, flatulence
- Abdominal pain
- Back pain
- Tiredness
Word of Advice
Regularly check blood sugar levels and inform your physician if you notice any changes such as increased or decreased blood sugar level. Female patients of reproductive potential use an alternative non-hormonal method of contraception, such as condoms, when the oral form of this medicine is used. Somatostatin 3000mcg Injection is given as a shot under your skin, into a muscle, or into a vein, based on your condition. This medicine may improve fertility in women and can cause unwanted pregnancies. Talk to your doctor if you have any concerns.
FAQs about Somastin 3000mcg Injection
Q1.
What do I have to inform the doctor before using Somatostatin 3000mcg Injection?
Tell your doctor if you are pregnant or breastfeeding or if you have kidney disease, liver disease, gallbladder disease, diabetes, psoriasis, heart or blood vessel problems, vitamin B12 deficiency, thyroid problems, or a history of gallstones before using Somatostatin 3000mcg Injection.
Q2.
What are the long-term side effects of Somatostatin 3000mcg Injection?
Somatostatin 3000mcg Injection, when used in the long term, can cause gallstones, which may lead to swelling of the gallbladder, bile ducts, or pancreas changes in blood sugar levels, heart rhythm problems, and high blood pressure.
Q3.
How to use Somatostatin 3000mcg Injection subcutaneous injection?
Your physician or nurse will teach you how to use this medicine. Make sure you understand all instructions before giving yourself an injection. You will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas.
Q4.
Does Somatostatin 3000mcg Injection result in weight gain and hair loss?
Yes, hair loss is Somatostatin's most common side effect, and it might also cause weight gain.
Fact Box of Somastin 3000mcg Injection
Molecule Name: Somatostatin | Therapeutic Class: Endocrine-metabolic agent |
Pharmacological Class: Somatostatin analogs | Indications: 1. Treat acromegaly 2. Relieve symptoms associated with some tumors of the GI tract 3. To prevent complications following surgery of the pancreas gland 4. To treat pituitary tumors that produce too much TSH |
References
- SANDOSTATIN LAR 10 mg powder and solvent for suspension for injection, Electronic Medicines Compendium (EMC), [Revised May 2022], [Accessed on 5th July 2023], https://www.medicines.org.uk/emc/files/pil.1038.pdf
- Highlights Of Prescribing Information - Somatostatin Injection. Access.fda.gov. [Revised 2019 Apr] [Accessed on 5th July 2023] https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/021008s043lbl.pdf
- Biocon, [Accessed on 5th July 2023], https://www.biocon.com/docs/prescribing_information/ccd/zomator_pi.pdf
- KD Tripathi, Essentials of Medical Pharmacology, Hormone and related drugs, 7th edition, 2013,237-239.
Disclaimer
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Author Details
Written By
Dr. Vijayalakshmi N.
BDS
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:29 AM (IST)
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