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Sorafekast 200mg Tablet 30's
Last updated on 31 Mar 2026 | 09:30 AM (IST)
₹941
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Introduction
Sorafekast 200mg Tablet belongs to the group of anti-cancer medicines. The Sorafekast composition contains the active ingredient Sorafenib, which is prescribed for the treatment of advanced renal cell carcinoma (kidney cancer), advanced hepatocellular carcinoma (Sorafekast for liver cancer) in patients who are not eligible for surgery, and differentiated thyroid carcinoma in patients who do not respond to radioactive iodine therapy.
The Sorafekast dosage should always be taken as directed by a qualified oncologist. Self-adjustment of dose is not recommended, as it may lead to unwanted side effects or reduced effectiveness.
When comparing Sorafenib vs Sorafekast, both contain the same active ingredient (Sorafenib), but differences may exist in terms of brand availability, cost, and formulation. In cases where Sorafekast is not available or suitable, doctors may suggest Sorafekast substitutes depending on the patient’s condition.
The Sorafekast price may vary depending on pharmacy, location, and supplier. Patients looking for bulk packs can also check the Sorafekast 200mg Tablet 30's price for cost-effectiveness.
Uses
Sorafekast uses are :
- Advanced renal cell carcinoma
- Advanced hepatocellular carcinoma that cannot be surgically treated
- Advanced papillary and follicular Hurtle cell thyroid carcinoma
How Sorafekast 200mg Tablet 30's works
Sorafekast Tablet works by inhibiting multiple receptor tyrosine kinases (enzymes), primarily vascular endothelial growth factor receptors and platelet-derived growth factor-β receptors. This prevents the development of blood vessels in tumour cells (angiogenesis) and arrests the growth and spread of the tumour cells to other organs.
Interaction of Sorafekast 200mg Tablet 30's with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, or herbal products that you are taking or have taken before the treatment. Certain medications tend to interact with Sorafekas tablets and decrease their effectiveness.
Storage conditions
Store below 30°C in a dry place.
How to take Sorafekast 200mg Tablet 30's
Take the Sorafekast tablet without food (1 hour before or 2 hours after a meal). Swallow with a glass of water. Do not break, crush or chew the tablets.
Safety Advice for Sorafekast 200mg Tablet 30's
Breast Feeding
Do not breastfeed during treatment with Sorafekast Tablet and for two weeks after the last dose. It is vital to let your physician know if you are breastfeeding or planning to breastfeed before starting treatment with this drug.
Alcohol
Avoid drinking alcohol while taking Sorafekast Tablet as it can cause unpleasant side effects like drowsiness, dizziness, or difficulty in concentrating.
Liver
Sorafekast tablets should be taken with caution in patients with severe liver disease. Consult your doctor for advice.
Lungs
Sorafekast tablet should be cautiously administered in patients with certain lung problems. Consult your doctor if you have any lung disorders.
Driving
This medicine could cause peripheral sensory neuropathy that causes an impact on driving. Hence, avoid driving or doing things that require focus during this treatment period.
Pregnancy
It is unsafe to use Sorafekast Tablet during pregnancy as it may harm the unborn baby. Inform your physician before starting this treatment if you are pregnant or think you might be pregnant. Your physician will conduct a pregnancy test before prescribing this medicine.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Sorafekast side effects are
Serious:
- Stevens Johnsons Syndrome and toxic epidermal necrosis
- Decreased blood flow to the heart
- Increased risk of bleeding (blood in urine, stool, vomit, cough, etc.)
- High BP
- Skin problems
- Liver problems
- Problems in wound healing
Common:
- Nausea, stomach pain, diarrhea
- Tiredness and weakness
- Infection
- Hair thinning and patchy hair loss
- Rash
- Weight loss
- Loss of appetite
- Low levels of calcium in the blood
- Flu-like illness
Expert tips
-
Seek immediate medical help if you experience:
-
Swelling in the lower legs
-
Rapid or irregular heartbeat
-
Difficulty breathing (may indicate heart problems)
-
-
Bleeding risk: Inform your doctor right away if you notice blood in stools or urine.
FAQs about Sorafekast 200mg Tablet 30's
Q1.
Can a diabetic person take Sorafekast Tablet?
Yes, Sorafekast Tablet is safe to be taken by diabetic individuals. However, only take it after seeing a doctor, as they may change the dose based on the patient's condition.
Q2.
What are the conditions under which Sorafekast Tablet use is prohibited?
Sorafekast Tablet is not recommended for people who are allergic to any of its ingredients, have squamous cell lung cancer, or are already taking carboplatin and paclitaxel.
Q3.
When should I stop taking Sorafekast Tablet as a treatment?
Sorafekast Tablet should be discontinued if a person experiences a major adverse effect that impairs their quality of life. If not, you must continue taking this medication until your physician instructs you to stop.
Q4.
What class of medication is Sorafekast Tablet?
Sorafekast Tablet belongs to the group of medicines called anti-tumor and tyrosine kinase inhibitors.
Q5.
I am pregnant. Can I use the Sorafekast Tablet during pregnancy?
Sorafekast tablets should not be taken during pregnancy as they may harm the unborn baby. It is better to use effective contraceptive methods to prevent pregnancy while taking this medicine or for at least six months after taking the final dose.
Fact Box of Sorafekast 200mg Tablet 30's
|
Molecule name | Sorafenib |
|
Therapeutic class |
Tyrosine kinase inhibitor |
|
Pharmacological class |
Anti-Neoplastics |
|
Indications |
1. Advanced renal cell carcinoma 2. Advanced hepatocellular carcinoma that cannot be surgically treated 3. Advanced papillary and follicular Hurtle cell thyroid carcinoma |
References
- Bayer (Pty) Ltd, [Revised on 22nd Apr 2016] [Accessed on 22 Nov 2022], https://www.bayer.com/sites/default/files/NEXAVAR_200_EN_PI.pdf
- Bayer HealthCare Pharmaceuticals Inc., US Food & Drug Administration, [Revised on Dec 2018] [Accessed on 22 Nov 2022]], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/021923s020lbl.pdf
- Ciplamed, [Revised on Dec 2017] [Accessed on 22 Nov 2022]], https://www.ciplamed.com/print-product-pdf/24207
- Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.
- KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.
Disclaimer
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Author Details
Written By
Dr. Deva Prasath S.
Pharm D
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:30 AM (IST)
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