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14% Off

Syntran SB 65mg Capsule

Prescription Required

Salt Composition : Itraconazole

Manufacturer : GLENMARK PHARMACEUTICALS LTD

Origin of Medicine : India

MRP: 140
Price : 120
You Save : 20 (14%)

10 Capsule(s) In A Strip

Pincode
Delivery By -

Introduction to Syntran Sb 65mg Capsule

Syntran SB 65mg Capsule contains an active component of Itraconazole. It is a potent antifungal agent utilised to combat diverse fungal infections in individuals. As a member of the triazole antifungal class, this medication demonstrates great efficacy against a wide spectrum of fungal species, making it a valuable therapeutic option against challenging mycoses. This medication operates by interrupting ergosterol synthesis, a critical component in the fungal cell membrane, thereby stopping the fungal growth and replication. It serves as a front-line treatment for superficial and systemic fungal infections. 

Its wide-ranging antifungal activity targets yeasts and moulds responsible for various conditions, from skin infections to invasive diseases. Syntran SB 65mg Capsule treats fungal infections in nails, skin, mucous membranes, and systemic infections under specific circumstances. Regular liver function monitoring is essential during treatment. The medication is contraindicated in patients with known hypersensitivity to Itraconazole or its components. It should not be used during pregnancy and is not recommended during breastfeeding.


Uses of Syntran Sb 65mg Capsule

Syntran SB 65mg Capsule treats the following:

  • Superficial fungal infections (skin, nails, mucous membranes).
  • Systemic fungal infections
  • Onychomycosis (fungal nail infection)
  • Vaginal candidiasis (yeast infection)
  • Aspergillosis histoplasmosis
  • Cryptococcosis
  • Prophylaxis in immunocompromised patients
  • Fungal pneumonia

Therapeutic Effects of Syntran Sb 65mg Capsule

Itraconazole exerts its therapeutic effects by inhibiting the synthesis of ergosterol, a vital component of the fungal cell membrane. This disruption weakens the membrane's integrity, contaminating essential cellular components and inhibiting fungal growth and replication. As a result, this medicine effectively treats various fungal infections, including superficial and systemic mycoses caused by susceptible fungi, relieving symptoms and promoting recovery in affected individuals.


Interaction of Syntran Sb 65mg Capsule with other drugs

Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Itraconazole, reducing effectiveness by causing undesirable side effects.


More Information about Syntran Sb 65mg Capsule

  • Store at room temperature, between 20°C to 25°C (68°F to 77°F).
  • Keep away from moisture, heat, and light.
  • It should not be frozen.
  • Keep away from children and pets.

How to consume Syntran Sb 65mg Capsule

Syntran SB 65mg Capsule is available in oral capsules. Your healthcare provider will determine the dosage of this medication based on your medical condition. It is crucial to adhere to their prescribed form and dosage for safe and effective treatment.


Safety Advices for Syntran Sb 65mg Capsule

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Pregnancy

  

Syntran SB 65mg Capsule is generally not recommended during pregnancy, especially during the first trimester. If a woman becomes pregnant while taking this medicine, she should promptly inform her healthcare provider.

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Breast Feeding

  

Syntran SB 65mg Capsule is known to be excreted into breast milk, and its use during breastfeeding is generally not recommended. There is a risk of potential harm to the nursing infant due to the presence of the drug in breast milk. 

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Lungs

  

If you are having any problems related to the lungs, it's essential to inform your healthcare provider about any existing medical conditions before starting Syntran SB 65mg Capsule treatment.

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Liver

  

If you have a history of liver disease or are experiencing liver-related symptoms, it is essential to inform your healthcare provider before starting Syntran SB 65mg Capsule.

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Alcohol

  

To ensure the safe use of Syntran SB 65mg Capsule, it is best to avoid alcohol during treatment.

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Driving

  

Syntran SB 65mg Capsule may cause side effects such as dizziness and blurred vision, impairing driving ability.


Side Effects of Syntran Sb 65mg Capsule

Syntran SB 65mg Capsule causes some side effects like all medications, although not everyone will experience them. 

Serious:

  • Jaundice
  • Dark urine
  • Allergic reactions (hives or swelling of the face, lips, tongue, or throat)


Common:

  • Nausea.
  • Vomiting
  • Stomach pain
  • Headache
  • Dizziness
  • Skin rash
  • Muscle or joint pain
  • Changes in taste sensation (dysgeusia)

Word of Advice

Regular monitoring of liver function is crucial, particularly in individuals with pre-existing liver conditions or a history of liver disease, as the medication can cause liver toxicity. If you experience any signs of an allergic reaction, such as difficulty breathing or swelling, seek immediate medical attention. Additionally, Itraconazole may prolong the QT interval, leading to irregular heart rhythms, so patients with a history of heart rhythm disorders require close monitoring. For pregnant or breastfeeding individuals, it is essential to consult a healthcare provider before using this medication due to potential risks. Tendon disorders have been reported with this medication, so promptly report any tendon pain or inflammation to your healthcare provider. Elderly patients may be more susceptible to certain side effects, requiring close monitoring and potential dosage adjustments. By adhering to these precautions and communicating any concerns with your healthcare provider, you can ensure a safe and successful treatment experience with this medication.


FAQs

Q 1. Can I use Syntran SB 65mg Capsule for a common cold or flu?

No, Syntran SB 65mg Capsule is specifically used to treat fungal infections and is ineffective against viral infections like the common cold or flu.

Q 2. Can I stop taking Syntran SB 65mg Capsule once my symptoms improve?

No, it is essential to complete the full course of treatment even if your symptoms improve. Stopping early may lead to the return of the infection or the development of resistant fungal strains.

Q 3. What should I do if I miss a dose of Syntran SB 65mg Capsule?

If you miss a dose, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.


Fact Box of Syntran Sb 65mg Capsule

Molecule name: Itraconazole

Therapeutic class: Antifungal agent

Pharmacological class: Azoles



 

Indications: 

  1. Superficial fungal infections (skin, nails, mucous membranes).
  2. Systemic fungal infections
  3. Onychomycosis 
  4. Vaginal candidiasis 
  5. Aspergillosis histoplasmosis 
  6. Cryptococcosis
  7. Prophylaxis in immunocompromised patients
  8. Fungal pneumonia

References

1. Accord Healthcare Limited, Electronic Medicines Compendium (EMC), [Revised on Jan 2021] [Accessed on 26th Jul 2023], https://www.medicines.org.uk/emc/files/pil.5914.pdf 

2. KD Tripathi, Antifungal Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 838-848.

3. Harry W. Lampiris, Daniel S. Maddix, Antifungal Agents, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 853-862.

4. S.H. Ibbotson, R.S. Dawe, Skin Disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 1249-1305.

5. Sanico N.V., FDA (Food and Drug Safety Administration)  [Revised on April 2001] [Accessed on 26th Jul 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/022484s000lbl.pdf 


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