TAXOCARE 120MG INJECTION uses are

• Non-small cell lung cancer

• Breast cancer

• Stomach or gastric cancer

• Prostate cancer

• Head and neck cancer

Docetaxel works by binding to a protein called beta-tubulin, which helps cells grow and divide. By doing this, it stops cancer cells from dividing properly and prevents the formation of structures needed for cell division. Additionally, docetaxel reduces the activity of a gene called BCL2, which usually helps cancer cells survive. By lowering this gene's activity, the treatment helps cancer cells become more sensitive to natural cell death processes, making it easier for the body to fight against the cancer.

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Taxocare 120mg Injection and cause undesirable side effects.

• Keep Taxocare 120mg Injection out of sight and reach of children.

• Do not store above 25°C.

• Do not use this medicine after the expiry date.

It will be administered through an intravenous infusion directly into one of your veins by a healthcare professional. Your doctor will decide the suitable dose of Taxocare 120mg Injection for you based on your weight and overall health.

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. TAXOCARE 120MG INJECTION side effects are

Serious:

• Severe allergic reactions

• Severe fluid retention

• Severe skin problems

• Swelling of the small intestine and colon

Common:

• Headache, dizziness

• Risk of infections

• Low blood cell count

• Loss of appetite

• Trouble sleeping

• Joint or muscle pain

• Alteration in the sense of taste

• Eye problems, bleeding from the nose

• Nausea, vomiting

• Diarrhea, constipation

• Abdominal pain

• Hair loss, change in color of your nails

• Change or absence of menstrual period

• Weight loss

• Tiredness

• Dry mouth

• High blood sugar

• Decreased blood pressure, rapid heartbeat

• Women of reproductive age must use effective contraception during treatment and for six months after it ends.

• Men receiving this treatment should avoid fathering a child and use reliable contraception for six months after therapy.

• Taxocare 120mg Injection can lower white blood cell counts, increasing the risk of infection.

• Blood tests will be done before each dose. If white blood cell levels are too low, treatment may be delayed or supportive medicines may be given.

• After the infusion, you will be monitored closely for side effects and given supportive care if needed.

• On chemotherapy days, eat small, light meals at regular intervals and avoid skipping meals or eating fatty, greasy, or spicy food.

• Patients should communicate openly with their doctor and ask questions whenever they have concerns.

1. Seacross Pharma (Europe) Ltd, Electronic medicines compendium (EMC), [Revised on May 2022] [Accessed on Oct 2023], https://www.medicines.org.uk/emc/files/pil.7206.pdf
2. Sanofi-aventis US LLC, US Food and Drug Administration (FDA), [Revised on May 2020] [Accessed on Oct 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/020449s084lbl.pdf
3. Angela M Davies et al. Docetaxel in non-small cell lung cancer: a review; Expert Opinion on Pharmacotherapy; Published on April 2003; Accessed on 26/10/2023; https://pubmed.ncbi.nlm.nih.gov/12667118/
4. Katherine A Lyseng-Williamson, Caroline Fenton; Docetaxel: a review of its use in metastatic breast cancer; Drugs; Published on 2005; Accessed on 26/10/2023; https://pubmed.ncbi.nlm.nih.gov/16296875/
5. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1707 - 1709.
6. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 866.