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At MrMed, we redefine accessibility to specialty medicines by offering comprehensive patient care services across India, serving customers and shipping medicines only within India. Whether you're in bustling metros like Mumbai, remote towns on the outskirts of Tamil Nadu, or quaint villages in Arunachal Pradesh, our extensive delivery network spans over 3,500 cities, including Indore, Jaipur, Coimbatore, Patna, Bhopal, Visakhapatnam, and more.

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  3. Tenecterel 40mg Injection

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Quick summary
Quick Summary

Tenecterel 40mg Injection

Prescription Required
Cold Chain Required
tenecteplase
Written By:Dr. Vijayalakshmi N.BDS Reviewed By:Dr. Tejashwin AdigaMBBS

Last updated on 31 Mar 2026 | 09:29 AM (IST)

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Prescription Required
Required
Cold Chain Required
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Salt Composition

TENECTEPLASE

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RELIANCE LIFE SCIENCES PVT LTD


Prepaid Only. Non-Returnable.

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1 Vial(s)

1 Vial(s)

₹ 35625.0/Unit

1 VIAL(s)


Prescription Required
Prescription Required
Cold Chain Required
Cold Chain
Info

Salt Composition

TENECTEPLASE

Marketer

RELIANCE LIFE SCIENCES PVT LTD


Prepaid Only. Non-Returnable.

Info
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₹ 31407.00/injection

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Introduction to Tenecterel 40mg Injection

Tenecterel 40mg Injection belongs to the antiplatelet agent category, containing the active ingredient Tenecteplase. It is used to prevent blood clots in patients with acute coronary syndrome (ACS), including unstable angina or myocardial infarction (heart attack).

This drug is contraindicated in individuals with known hypersensitivity or allergic reactions to other ingredients in it. If you are scheduled for surgery (including dental work), it is important to inform your doctor. Due to the increased risk of bleeding associated with this drug, your physician may advise you to stop taking the medication five days prior to the surgery.  If you develop irregular breathing patterns such as speeding up, slowing down, or experiencing short pauses in breathing, it is recommended to consult your doctor for further evaluation.

Tenecterel 40mg Injection is not recommended during pregnancy or if there is a possibility of becoming pregnant. It is advised for women to use appropriate contraceptive measures to prevent pregnancy while using this medication. If you are breastfeeding, it's important to consult with your physician before taking this drug.

Uses of Tenecterel 40mg Injection

  • Prevent blood clots in patients with acute coronary syndrome (ACS)

Therapeutic Effects of Tenecterel 40mg Injection

Tenecteplase works by inhibiting platelet activation and aggregation. It specifically blocks a receptor called P2Y12 on the platelets, preventing them from clumping together and forming blood clots. This helps reduce the risk of heart-related events in individuals with ACS.

Interaction of Tenecterel 40mg Injection with other drugs

Inform your physician about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications such as rosuvastatin, rifampicin, phenytoin, digoxin, cyclosporine, verapamil and opioids may interact with Tenecterel 40mg Injection and reduce effectiveness by causing undesirable side effects.

More Information about Tenecterel 40mg Injection

  • Do not store Tenecterel 40mg Injection above (30°C).
  • Keep out of reach of children.

How to consume Tenecterel 40mg Injection

Take the Tenecterel 40mg Injection as advised by your physician. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.

Safety Advice for Tenecterel 40mg Injection

Breast Feeding-Consult your doctor

Breast Feeding

Consult Your Doctor

If you are breastfeeding, it's important to consult with your physician before taking Tenecterel 40mg Injection.

Alcohol-Consult your doctor

Alcohol

Consult Your Doctor

It is unknown whether consuming alcohol interacts with Tenecterel 40mg Injection. Please consult your doctor for more advice.

Liver-Consult your doctor

Liver

Consult Your Doctor

It is unknown whether Tenecterel 40mg Injection is safe for patients with lung problems. Inform your physician if you have lung disease before starting the treatment.

Lungs-unsafe

Lungs

Unsafe

Inform your doctor if you have lung disease because Tenecterel 40mg Injection should be used cautiously with a lung condition.

Driving-safe

Driving

Safe

Tenecterel 40mg Injection are not known to cause drowsiness or impair driving ability, so they are generally considered safe for use while driving or operating machinery.

Pregnancy-unsafe

Pregnancy

Unsafe

Tenecterel 40mg Injection is not recommended during pregnancy or if there is a possibility of becoming pregnant. It is advised for women to use appropriate contraceptive measures to prevent pregnancy while using this medication

Side Effects of Tenecterel 40mg Injection

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious: 

  • Shortness of breath
  • Blood clotting problem called TTP (purplish spots in the mouth or mouth, fever, confusion, yellowing of the eyes or skin, fever)
  • Fainting
  • Bleeding (red or black stools, coughing up or vomiting with blood, red, pink, or brown urine)


Common:

  • Headache
  • Indigestion
  • Nausea
  • Constipation
  • Rash, itching
  • Pain and swelling in the joints
  • Blurred vision
  • Bleeding gums
  • Bruising

Word of Advice

Since Tenecterel 40mg Injection affects platelet production, it's essential to take precautions to avoid injuries and bleeding. Be cautious when engaging in activities that may increase your risk of injury, and report any unusual bleeding or bruising to your physician.

FAQs about Tenecterel 40mg Injection

Q1.

How does Tenecterel 40mg Injection work?

Tenecteplase works by inhibiting platelet activation and aggregation. It specifically blocks a receptor called P2Y12 on platelets, which prevents them from sticking together and forming blood clots. This helps maintain blood flow and reduce the risk of cardiovascular events in patients with ACS.

Q2.

How is Tenecterel 40mg Injection taken?

Tenecterel 40mg Injection is taken orally in tablet form. The usual recommended dose for ACS patients is 180 mg as a loading dose, followed by 90 mg twice daily. It is important to follow the dosing instructions provided by your healthcare provider.

Q3.

What are the common side effects of Tenecterel 40mg Injection?

Common side effects of Tenecterel 40mg Injection may include bleeding, shortness of breath, headache, dizziness, nausea, and fatigue. It is important to seek medical attention if you experience any signs of bleeding, such as prolonged or excessive bleeding from cuts, blood in urine or stool, or unexplained bruising.

Q4.

Are there any drug interactions with Tenecterel 40mg Injection?

Tenecterel 40mg Injection may interact with other medications, including prescription drugs, over-the-counter medications, and herbal supplements. It is crucial to inform your healthcare provider about all the medications you are taking to avoid potential interactions that may affect the safety or efficacy of Tenecteplase.

Q5.

What should I do if I miss a dose of Tenecterel 40mg Injection?

If you miss a dose of Tenecterel 40mg Injection, take it as soon as you remember and then continue with your regular dosing schedule. Do not take a double dose to make up for a missed dose unless advised by your healthcare provider.

Fact Box of Tenecterel 40mg Injection

Molecule name: Tenecteplase

 

Therapeutic class: Thrombolytics 

Pharmacological class: Tissue-plasminogen activator (tPA)

Indications: 

Prevent blood clots

 

References

  1. Boehringer Ingelheim Ltd, Electronic medicines compendium (EMC), [ Revised on Feb 2023] [ Accessed on 18th July 2023], https://www.medicines.org.uk/emc/files/pil.3013.pdf
  2. Genentech, Inc, US Food and Drug Administration, [ Revised on Feb 2018] [ Accessed on 18th July 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/103909s5187lbl.pdf
  3. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Modulation of cardiovascular functions, 12th edition, 2011, 866.
  4. KD Tripathi, Essentials of Medical Pharmacology, Drugs affecting coagulation, bleeding and thrombosis, 7th edition, 2013, 627

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

Did you find this information helpful?

Author Details
Dr. Vijayalakshmi N.

Written By

Dr. Vijayalakshmi N.

BDS


Dr. Tejashwin Adiga

Reviewed By

Dr. Tejashwin Adiga

MBBS


Last updated : 31 Mar 2026 | 09:29 AM (IST)

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