Tevimbra 100mg Injection is a type of cancer treatment that helps your body’s immune system fight cancer more effectively. It contains Tislelizumab, which belongs to a group of medicines called immune checkpoint inhibitors. These medicines don’t attack cancer directly; instead, they help your immune system recognise and destroy cancer cells.

Doctors usually prescribe this medicine for certain advanced cancers, especially when other treatments haven’t worked. Tevimbra 100mg Injection is given through an IV drip in a hospital or cancer centre under a doctor’s supervision. While it can be very effective, it may also cause some serious side effects if your body’s immune system becomes too active. That’s why it’s important to be closely monitored during treatment. This medicine isn't safe for everyone, especially those with autoimmune diseases, severe liver problems, or women who are pregnant or breastfeeding.

Tevimbra 100mg Injection is approved to treat the following cancers:

1. Classical Hodgkin lymphoma (after trying at least two other treatments)

2. Non-small cell lung cancer (NSCLC) that has spread and doesn’t respond to chemotherapy

3. Liver cancer (after using a medicine called Sorafenib)

4. Oesophageal cancer that has worsened despite other treatments

Tislelizumab helps your immune system do its job better. Normally, cancer cells trick the immune system into ignoring them. This medicine blocks one of those tricks so that your immune cells can "see" and attack the cancer. You can think of it as taking the blindfold off your immune system, so it knows where the danger is and can fight back. It doesn't kill the cancer cells directly, but gives your immune system the power to do it.

Some medicines can interfere with how Tevimbra 100mg Injection works or increases your risk of side effects. Always tell your doctor about everything you're taking, even herbal supplements and over-the-counter pills.

Here are some drugs to watch out for:

• Steroids (like Prednisone): May reduce how well this medicine works

• Drugs that suppress the immune system (like Tacrolimus): Can increase your risk of infections

• Liver-damaging medicines (like Methotrexate or Isoniazid): Could increase the risk of liver issues

• Live vaccines: Should be avoided during treatment

• Some antibiotics or antifungals (like Rifampin or Ketoconazole): May affect how your body processes this medicine

Always check with your doctor or pharmacist before starting any new medication while on this treatment.

• Store in a refrigerator at 2°C to 8°C (36°F to 46°F) in the original carton to protect from light.  

• Do not freeze. 

• Do not shake.

Tevimbra 100mg Injection is available as an intravenous (IV) infusion and is usually given every 2 to 3 weeks, depending on your treatment plan. The infusion is done slowly over approximately 30–60 minutes at a clinic or hospital. It should not be taken with food, as it's not an oral medication. Doses are based on body weight or as fixed dosing per the latest clinical guidelines.

Common side effects (may not need medical attention unless severe):

• Tiredness or fatigue

• Loss of appetite

• Skin rash or itchiness

• Joint or muscle pain

• Diarrhoea or upset stomach

• Mild nausea

Serious side effects (contact your doctor right away):

• Shortness of breath or chest pain (could be lung inflammation)

• Severe stomach pain or persistent diarrhoea

• Yellowing of eyes or skin (could mean liver trouble)

• Changes in heartbeat or blood pressure

• Sudden weight changes or mood swings (may indicate hormonal changes)

• Don’t skip follow-up scans and blood tests: Regular monitoring is key while you're on Tevimbra 100mg Injection. These tests help your doctor catch any immune-related side effects early, even before you feel symptoms.

• Watch for warning signs like breathing issues or severe fatigue: If you suddenly feel short of breath, unusually tired, or notice yellowing of your eyes/skin, inform your doctor immediately. These could be signs of serious side effects.

• Tell every doctor you're on immunotherapy: Whether you're visiting a dentist, dermatologist, or any other specialist, always mention that you're receiving Tevimbra 100mg Injection. It helps prevent drug interactions or treatment conflicts.

• Avoid live vaccines during treatment: Stay away from live or weakened virus vaccines (like oral polio, MMR, or nasal flu sprays) while on Tevimbra 100mg Injection. Your immune system is being modified, and such vaccines can be risky.

• Use effective contraception: If you're of childbearing age, make sure to use reliable birth control during treatment and for at least 4 months after the last dose. Tevimbra 100mg Injection can harm an unborn baby.