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Themiset Injection
Last updated on 31 Mar 2026 | 09:31 AM (IST)
₹129
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1 VIAL(s) OF 5ML
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₹129
MRP: ₹247.44
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48% Off
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Introduction to Themiset Injection
Themiset Injection is an antiemetic drug belonging to the class of 5-HT3 receptor antagonists, containing the active ingredient Palonosetron. It is used to prevent and treat nausea, vomiting, or sickness caused by cancer treatments such as chemotherapy, radiotherapy, or after surgery. Nausea is characterised by stomach pain and the urge to vomit.
The common side effects that are likely to occur with this medicine are hives, swollen face, breathing trouble, and chest pain. Inform your healthcare provider if these side effects concern you or persist for longer than usual. It is given right away or later with anticancer medicines. It is usually given up to 24 hours while recovering from anesthesia after surgery.
Talk to your physician if you have a history of repeated constipation, blockage in the bowel, heart problems, or imbalance of certain minerals in your blood (such as magnesium and potassium). This medicine should not be used if you are allergic to this drug. Tell your physician about all the medications you have been taking recently, including herbal medicines and supplements, before taking the Themiset Injection.
Uses of Themiset Injection
- Postoperative nausea and vomiting.
- Chemotherapy-induced nausea and vomiting.
Therapeutic Effects of Themiset Injection
It is a type of serotonin receptor antagonist, which works by blocking the action of serotonin in the body that induces nausea and vomiting. The chemotherapeutic trigger zone(CTZ) contains the receptor serotonin, when this CTZ is stimulated, vomiting occurs. It prevents the signals from serotonin and helps to reduce the symptoms of nausea and vomiting.
Interaction of Themiset Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Themiset Injection and reduce effectiveness by causing undesirable side effects.
More Information about Themiset Injection
- Store Themiset Injection in the original package at room temperature (25°C). Do not freeze.
- Keep it out of reach from children and pets.
- It is important to get the dose at the scheduled time. If you missed the schedule, contact your doctor and reschedule the dose.
How to consume Themiset Injection
The medicine will be administered to you by a healthcare professional in a hospital setting. Themiset Injection is usually given about 30 minutes before you receive your anti-cancer medicine (chemotherapy) or right before anaesthesia for surgery.
Safety Advice for Themiset Injection
Breast Feeding
It is not known if Themiset Injection passes into your breast milk or if it will affect your baby or your breast milk. Please consult your doctor before breastfeeding.
Alcohol
It is unknown whether consuming alcohol interacts with Themiset Injection. Please consult your doctor for more advice.
Liver
It is unknown whether Themiset Injection can be administered to patients with liver disorders. Inform your physician if you have any liver problems before starting treatment with this drug.
Lungs
It is not known whether Themiset Injection can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Driving
It is unsafe to drive vehicles or operate heavy machinery after taking Themiset Injection because it contains a small amount of alcohol which may cause dizziness and impair your concentration.
Pregnancy
It is unknown whether Themiset Injection can be administered during pregnancy. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
Side Effects of Themiset Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious
- Hives
- Swollen face
- Breathing trouble
- Chest pain
Common
- Headache
- Fatigue
- Dizziness
- Abdominal pain
Word of Advice
Talk to your physician if you have a history of repeated constipation, blockage in the bowel, heart problems, or imbalance of certain minerals (such as potassium and magnesium) in your blood before taking Themiset Injection Inform your doctor or nurse if you are taking any medicines that affect your heartbeat because they could cause a heartbeat problem when taken with this injection.
FAQs about Themiset Injection
Q1.
What are the possible side effects of Themiset Injection?
It can cause serious allergic reactions like hives, swollen face, breathing trouble, and chest pain. Some common side effects include headache and constipation.
Q2.
When should you take the Themiset Injection?
The first dose of this drug is typically taken before the start of your surgery, chemotherapy, or radiation treatment.
Q3.
How does an Themiset Injection work?
Themiset Injection works by blocking the action of a chemical called serotonin, which is involved in causing nausea and vomiting.
Q4.
Who should not take an Themiset Injection?
Themiset Injection should not be taken by individuals who are allergic to it or its ingredients.
Q5.
What forms does the Themiset Injection come in?
Themiset Injection is available in the injection form.
Fact Box of Themiset Injection
Molecule name: Palonosetron | Therapeutic class: Antiemetics |
Pharmacological class: 5-HT3 receptor antagonists | Indications: 1.Postoperative nausea and vomiting. 2.Chemotherapy induced nausea and vomiting. |
References
- Helsinn Birex Pharmaceuticals Ltd, Electronic medicines compendium (EMC), [Revised on Dec 2021] [ Accessed on 01st March 2023], https://www.medicines.org.uk/emc/files/pil.513.pdf
- Fresenius Kabi, US Food and Drug Administration, [Revised on Dec 2018] [Accessed on 01st March 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/208109s001lbl.pdf
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Treatment of disorders of bowel motility and water flux, 12th edition, 2011, 1341.
- KD Tripathi, Essentials of Medical Pharmacology, Antiemetic, prokinetic and digestant drugs, 7th edition, 2013, 669.
Disclaimer
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Author Details
Written By
Dr. B. Deiva
Pharm D
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:31 AM (IST)
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