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Tofatas 5mg Tablet 14's
Last updated on 01 Apr 2026 | 07:25 AM (IST)
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14 TABLET(s) IN A STRIP
Tofatas 5 mg Tablet 14’s is an immunosuppressive medicine used to treat autoimmune conditions such as Rheumatoid Arthritis. It contains tofacitinib, which works by blocking specific enzymes involved in the immune response, thereby reducing inflammation, pain, and joint damage. This pack of 14 tablets is typically prescribed as part of a short term or ongoing treatment plan and should be taken under careful medical supervision as directed by a doctor.
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Introduction
Tofatas 5mg Tablet 14's is a medicine used to treat autoimmune conditions like rheumatoid arthritis, psoriatic arthritis, and ulcerative colitis. It helps reduce pain, swelling, and joint stiffness by targeting the body’s immune response. This medication is often prescribed when other treatments haven't worked well enough or are not suitable.
Do not take Tofatas 5mg Tablet 14's if you are allergic to tofacitinib or any other ingredients of this medicine. Inform your healthcare professional if you have any symptoms of an infection, such as fever, sweating, chills, muscle aches, cough, shortness of breath, weight loss, skin sores, difficulty or pain when swallowing, diarrhoea, or stomach pain.
Before initiating the treatment, inform your physician if you have kidney, heart, lung, or liver problems, a history of tuberculosis, high blood pressure, or high cholesterol, and also if you are a current or past smoker.
Uses
Tofatas 5mg Tablet 14'ss is used in the treatment of the following:
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Rheumatoid arthritis
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Psoriatic arthritis
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Ankylosing spondylitis
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Ulcerative colitis
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Polyarticular juvenile idiopathic arthritis
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Juvenile psoriatic arthritis
How Tofatas 5mg Tablet 14'sworks
Tofatas 5mg Tablet 14's belongs to a class of medicines called Janus Kinase (JAK) inhibitors. It works by blocking certain enzymes (JAKs) that are involved in the inflammation process. By interfering with these pathways, it helps control an overactive immune system and reduce inflammation in the body.
Interaction of Tofatas 5mg Tablet 14's with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, vaccinations, nutritional and vitamin supplements, and herbal products. Certain medications may interact with the effects of tofacitinib and reduce its effectiveness by causing undesirable side effects.
Storage conditions
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Store tofacitinb.NPP at room temperature (20°C to 25°C)
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Keep the tablet away from the reach of children and pets.
How to take Tofatas 5mg Tablet 14's
Take Tofatas 5mg Tablet 14's exactly as prescribed by your doctor. It is usually taken by mouth with or without food. Swallow the tablet whole with a glass of water. Do not crush or chew the tablet.
Safety Advices
Pregnancy
Tofatas 5mg Tablet 14's is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for at least 4 weeks after your last dose is necessary.
Breast Feeding
Breastfeeding is not recommended in patients taking Tofatas 5mg Tablet 14's because the medicine passes into the breast milk in small amounts and may harm your baby.
Lungs
It is unknown whether Tofatas 5mg Tablet 14's can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Liver
Tofatas 5mg Tablet 14's is unsafe when administered in patients with severe liver diseases. Dose adjustments are necessary in severe liver failure. Inform your physician if you have liver problems before initiating the therapy.
Alcohol
It is unknown whether it is safe to consume alcohol when taking Tofatas 5mg Tablet 14's. Consult your doctor for more advice.
Driving
The drug has no or limited effect on your ability to drive or operate heavy machines. If you face any difficulties, consult your doctor for more advice.
Side Effects of Tofatas 5mg Tablet 14's
Like all medicines, Tofatas 5mg Tablet 14's may cause side effects in some people. Common ones include:
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Headache
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Diarrhea
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High blood pressure
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Increased risk of infections (e.g., cold, flu)
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Elevated cholesterol levels
Contact your doctor if any side effects persist or worsen.
Expert Tips
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Take it at the same time each day for best results.
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Avoid live vaccines while taking this medicine.
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Inform your doctor if you experience signs of infection like fever or sore throat.
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Do not stop the medication without consulting your healthcare provider.
FAQs
Q1.
What are the cautions of Tofatas 5mg Tablet 14's?
Tell your doctor immediately if you start to have swelling of your face, lips, tongue, throat, arms, or legs or if you are having trouble swallowing or breathing. Tofatas 5mg Tablet 14's can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection.
Q2.
Does Tofatas 5mg Tablet 14's cause high cholesterol?
Increased cholesterol levels are one of the side effects of Tofatas 5mg Tablet 14's, your doctor may take regular blood tests to check for serious side effects.
Q3.
Can Tofatas 5mg Tablet 14's cause depression?
No, Tofatas 5mg Tablet 14's does not cause depression. However, many people who have autoimmune conditions also have symptoms of depression. If you're having symptoms of depression, see your doctor right away.
Q4.
Does Tofatas 5mg Tablet 14's cause blood clots?
Yes, blood clots are reported in patients using Tofatas 5mg Tablet 14's for a longer period. Inform your physician if you face any symptoms of a blood clot.
Fact box
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Molecule name: Tofacitinib |
Therapeutic class: Anti-rheumatic, Anti-inflammatory agents |
|
Pharmacological class: Tyrosine kinase inhibitor |
Indications: 1. Rheumatoid arthritis 2. Psoriatic arthritis 3. Ankylosing spondylitis 4. Ulcerative colitis 5. Polyarticular juvenile idiopathic arthritis 6. Juvenile psoriatic arthritis |
References
1. Pfizer limited, Electronic Medicines Compendium (emc) [Revised Mar 2023] [Accessed on Mar 2024] https://www.medicines.org.uk/emc/product/2500/smpc
2. Pfizer limited, FDA, [Revised May 2018] [Accessed on Mar 2024] https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/203214s018lbl.pdf
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details

Written By
Dr. Vikas B S
Pharm D

Reviewed By
Dr. Abhishaanth Prabu
MBBS
Last updated : 01 Apr 2026 | 07:25 AM (IST)

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