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Trombonat 50mg Tablet
Last updated on 26 Sep 2026 | 08:41 AM (IST)
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Trombonat 50mg Tablet is a prescription thrombopoietin receptor agonist used to treat low platelet counts in chronic immune thrombocytopenic purpura, hepatitis C, and aplastic anemia. It contains Eltrombopag, which helps increase platelet production and reduce bleeding risks. Trombonat is used under medical supervision as part of platelet‑support treatment protocols.
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Introduction
Trombonat 50mg Tablet is an anticoagulant drug belonging to the thrombopoietin (TPO) receptor agonist category, containing the active ingredient Eltrombopag. It is commonly used as a Trombonat Tablet for ITP (primary immune thrombocytopenia) and also to manage low platelet counts caused by hepatitis C (HCV) infection. Platelets are blood cells that support blood clotting and protect blood vessels. Low platelet levels can cause severe bruising or bleeding. This medicine is also prescribed as a Trombonat Tablet for aplastic anaemia in adults with severe bone marrow failure when the body cannot produce enough new blood cells.
Patients searching for Trombonat 50mg substitute or alternative brands should only switch medicines under the guidance of a doctor, as platelet-management therapy requires personalised dosing and monitoring. Some individuals also compare Trombonat 50mg vs Revolade 50mg, as both contain Eltrombopag but may differ in pricing and manufacturer availability. The Natco Trombonat 50mg price may vary by location, pharmacy, and prescription support programs.
Tell your doctor about all medications, vitamin supplements, and herbal remedies you take, as interactions may affect treatment safety and response. Individuals often prefer to buy Trombonat 50mg Tablet online through trusted pharmacies for convenience and availability, especially when continuing long-term platelet-support therapy.
Uses
Trombonat 50mg Tablet uses to treat,
Low platelet counts are caused by primary immune thrombocytopenia (ITP) or hepatitis C virus (HCV) infection.
Severe aplastic anaemia
How Trombonat 50mg Tablet works
Trombonat 50mg Tablets stimulate megakaryocytes (the large bone marrow cells) responsible for producing platelets. By raising the number of platelets in the blood, this drug prevents bleeding and bruising.
Interaction of Trombonat 50mg Tablet with other drugs
Inform your healthcare provider about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications include antacid medicines, statins, ciclosporin, methotrexate, topotecan, lopinavir, or ritonavir, and vitamin and mineral supplements may interact with Trombonat 50mg Tablet and reduce effectiveness by causing undesirable side effects.
Storage conditions
Store Trombonat 50mg Tablet at room temperature (25°C).
Keep the medicine out of reach of children and pets.
How to take Trombonat 50mg Tablet
It is an orally available prescription drug. Your doctor will decide the dose and duration of the drug based on the disease condition and other factors. Always take an Trombonat 50mg Tablet as prescribed by your doctor. Take the tablet with or without food. Do not chew, crush, or break the tablet. Swallow the whole tablet with water.
Safety Advice for Trombonat 50mg Tablet
Breast Feeding
It is not known whether Trombonat 50mg Tablet passes into breast milk. If you are breastfeeding or planning to breastfeed, tell your doctor.
Alcohol
It is unknown whether alcohol may interact with the Trombonat 50mg Tablet. Inform your physician if you drink alcoholic beverages.
Liver
Trombonat 50mg Tablet should be cautiously administered in patients with severe liver diseases. Dose adjustments are necessary for severe liver failure. Inform your doctor if you have liver issues before initiating the therapy.
Lungs
It is unknown whether Trombonat 50mg Tablet can be prescribed for patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Driving
Driving vehicles or operating heavy machinery is unsafe after taking the Trombonat 50mg Tablet. It may cause dizziness and impair concentration.
Pregnancy
Trombonat 50mg Tablet is not recommended for pregnant patients because it may cause fetal harm. You must inform your doctor if you are pregnant, suspecting, or planning to get pregnant during the treatment.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Trombonat 50mg Tablet side effects are
Common
Nausea
Diarrhoea, abdominal pain
Common cold
Cough
Respiratory tract infection
Back pain
High temperature, cough
Loss of appetite
Hair loss
Swelling in feet or hands
Headache, dizziness
Mouth and throat pain
Joint pain
Expert tips
Avoid consuming dairy products (cheese, butter, milk, milkshakes) within 2 hours before or 4 hours after taking Trombonat 50mg Tablet.
Do not take antacids or supplements containing iron, aluminium, magnesium, calcium, selenium, or zinc close to your dose.
If you miss a dose, take the next one at the regular scheduled time. Do not double the dose.
Do not stop taking this medicine without your doctor’s advice.
If treatment is stopped, your platelet count will be monitored weekly for four weeks.
Consult your doctor if you have any doubts or experience concerns while using this medicine.
FAQs about Trombonat 50mg Tablet
Q1.
What is ITP?
Immune thrombocytopenia, also known as ITP, is a rare blood disorder. People with ITP have insufficient platelets in their blood. A low platelet count can cause bruising and bleeding.
Q2.
Who should not use the Trombonat 50mg Tablet?
People with immune (primary thrombocytopenia (ITP) and children under one should not use Trombonat 50mg Tablets. It is also not suggested for people with severe aplastic anemia and hepatitis C.
Q3.
Will you be monitored during treatment with the Trombonat 50mg Tablet?
Yes, you will be monitored during the Trombonat 50mg Tablet. Your healthcare provider will regularly access your white blood cell, platelets, blood clotting factors, heart rate, eye test, and complete blood count.
Q4.
Is it safe to take a Trombonat 50mg Tablet on an empty stomach?
Yes, Trombonat 50mg Tablets should be taken on an empty stomach. Because antacids, mineral and vitamin supplements (iron, calcium, magnesium, aluminum, selenium, and zinc), dairy products, calcium-enriched foods, and fortified juices interfere with this drug absorption. So, please take them at least two hours before or four hours after taking the medication.
Q5.
What happens if you discontinue using the Trombonat 50mg Tablet?
If you discontinue using Trombonat 50mg Tablets suddenly, it decreases platelet count as it can lead to severe bleeding. However, telling your healthcare practitioner before discontinuing this medication is advisable.
Q6.
What is the procedure to store a Trombonat 50mg Tablet?
Store Trombonat 50mg Tablet at 25°C and out of the reach of children. After the expiration date, do not use this medication.
Fact Box
Molecule name | Eltrombopag |
Therapeutic class | Anticoagulant |
Pharmacological class | Thrombopoietin (TPO) receptor agonist |
Indications | 1. Low platelet counts caused by immune primary thrombocytopenia (ITP) or hepatitis C virus (HCV) infection. 2. Severe aplastic anaemia. |
References
- Novartis Pharmaceuticals UK Limited, Electronic medicines compendium (EMC), [ Revised on Jan 2022] [Accessed on 22 May 2023], https://www.medicines.org.uk/emc/files/pil.508.pdf
- GlaxoSmithKline, US Food and Drug Administration, [ Revised on October 2008] [Accessed on 22 May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/022291lbl.pdf
- Revolade, Annex I summary of Product Characteristics - European Medicines Agency. Available at: https://www.ema.europa.eu/en/documents/product-information/revolade-epar-product-information_en.pdf [Accessed on 22 May 2023].
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details
Written By
Dr. B. Deiva
Pharm D
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 26 Sep 2026 | 08:41 AM (IST)
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