All Substitutes
Loading...
Disclaimer
Did you find this information helpful?
Vabysmo 6mg Injection
Prescription Required
Salt Composition : Faricimab
Manufacturer : ROCHE PRODUCTS INDIA PVT LTD
Origin of Medicine : Switzerland
1 Vial(s)
Introduction to Vabysmo 6mg Injection
Vabysmo 6mg Injection contains the active ingredient Faricimab, a humanised bispecific antibody. It targets and inhibits two pathways: VEGF-A and Ang-2. This reduces fluid buildup, controls abnormal blood vessel growth, and stabilises retinal health.
Vabysmo 6mg Injection is used to treat conditions such as Diabetic Macular Edema (DME), Wet Age-Related Macular Degeneration (AMD), Retinal Vein Occlusion (RVO), and Myopic Choroidal Neovascularization (mCNV), which cause significant vision problems. Vabysmo 6mg Injection improves vision by addressing these underlying issues and promoting retinal stability.
Vabysmo 6mg Injection must be administered by a healthcare professional in a controlled setting. It can cause serious risks such as eye infections, retinal detachment, increased intraocular pressure, and blood clots, potentially leading to strokes or heart attacks.
Healthcare providers will determine the dosage and treatment schedule based on the patient’s condition. Regular monitoring and follow-up visits are essential for optimal results. Always consult your healthcare provider before starting Vabysmo 6mg Injection, especially if you are pregnant, breastfeeding, or planning pregnancy.
Uses of Vabysmo 6mg Injection
Vabysmo 6mg Injection treats the following eye conditions:
- Diabetic macular edema (DME)
- Wet age-related macular degeneration (AMD)
- Retinal vein occlusion (RVO)
- Myopic choroidal neovascularisation (mCNV)
Therapeutic Effects of Vabysmo 6mg Injection
Vabysmo 6mg Injection is a humanised bispecific antibody that targets VEGF-A and Ang-2. It suppresses endothelial cell growth and vascular permeability by binding to VEGF-A while promoting vascular stability and reducing sensitivity to VEGF-A by targeting Ang-2. The role of Ang-2 inhibition in treating nAMD and DME is not yet fully understood.
Interaction of Vabysmo 6mg Injection with other drugs
Inform your healthcare professional about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Some medicines interact with Vabysmo 6mg Injection may reduce effectiveness by causing undesirable side effects.
More Information about Vabysmo 6mg Injection
- Keep out of reach of children and pets.
- Vabysmo 6mg Injection should be stored refrigerated at temperatures between 2ºC to 8ºC
- Close the container tightly after use to maintain product integrity.
- Avoid direct sunlight and store in a cool, dry place.
How to consume Vabysmo 6mg Injection
Vabysmo 6mg Injection should be administered in a healthcare setting, typically by an eye care specialist. The dose will be determined by the doctor based on the specific condition being treated. It is given through an intravitreal injection (injection into the eye), and the treatment schedule may vary depending on the patient's condition and response to therapy. Always follow the doctor's instructions for dosing and administration.
Safety Advices for Vabysmo 6mg Injection
Pregnancy
It is unknown whether it is safe to use Vabysmo 6mg Injection during pregnancy. Please consult your healthcare provider before starting treatment with Vabysmo 6mg Injection.
Breast Feeding
It is unknown if Vabysmo 6mg Injection is safe to use while breastfeeding. Please consult your healthcare provider before use if you are breastfeeding.
Lungs
Before starting treatment with Vabysmo 6mg Injection, talk to your doctor if you have any lung conditions.
Liver
You need to inform your doctor if you have any liver disorders before starting treatment with Vabysmo 6mg Injection.
Alcohol
It is unknown if Vabysmo 6mg Injection is safe to use while having alcohol. Please consult your healthcare provider before using Vabysmo 6mg Injection.
Driving
After your treatment with Vabysmo 6mg Injection, you may have temporary vision problems (for example, blurred vision). Do not drive or use machines as long as these last.
Side Effects of Vabysmo 6mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Common Side Effects of Vabysmo 6mg Injection are:
- Conjunctival hemorrhage
- Vitreous floaters
- Retinal pigment epithelial tear
- Increased intraocular pressure & inflammation
- Eye pain & Ocular discomfort
- Vitreous haemorrhage
Serious Side Effects of Vabysmo 6mg Injection are:
- Corneal abrasion
- Eye pruritus & Increased lacrimation
- Ocular hyperemia
- Blurred vision & Eye irritation
- The sensation of a foreign body in the eye
- Endophthalmitis
- Retinal tear
- Rhegmatogenous retinal detachment
Word of Advice
Vabysmo 6mg Injection can cause serious eye infections, retinal detachment, and temporary increases in eye pressure. It may also raise the risk of blood clots, especially in the first year. Your healthcare provider will decide the dosage and schedule, and a trained professional will administer the Vabysmo 6mg Injection in a healthcare setting. Always consult your doctor before starting or adjusting treatment, particularly if you are pregnant, breastfeeding, or of reproductive potential.
FAQs
Q 1. What is Vabysmo 6mg Injection used for?
Vabysmo 6mg Injection treats eye conditions like wet age-related macular degeneration, diabetic macular oedema, retinal vein occlusion, and myopic choroidal neovascularisation by targeting proteins that cause abnormal blood vessel growth and fluid leakage in the eye.
Q 2. Is Vabysmo 6mg Injection approved in India?
The active ingredient of Vabysmo 6mg Injection is Faricimab. Faricimab was first approved by the USFDA in January 2022 and is now available in over 90 countries, including India. More than 2 million doses have been administered globally.
Q 3. What are the risks of taking Vabysmo 6mg Injection?
The risks of taking Vabysmo 6mg Injection include eye infections, retinal detachments, and temporary increases in eye pressure. It may also increase the risk of blood clots, leading to serious events like stroke or heart attack. Your healthcare provider will monitor you for these risks during treatment.
Q 4. How many injections are needed for Vabysmo 6mg Injection?
The number of Vabysmo 6mg Injection needed depends on the condition being treated and the patient's response. Initially, patients may receive injections every 4 weeks, with the frequency adjusted based on their progress and the healthcare provider's assessment.
Q 5. What type of drug is Vabysmo 6mg Injection?
Vabysmo 6mg Injection is a biologic drug, specifically a bispecific antibody. It targets and inhibits two proteins, VEGF-A and Ang-2, to treat eye conditions by reducing abnormal blood vessel growth and fluid leakage.
Fact Box of Vabysmo 6mg Injection
Molecule Name: Faricimab | Therapeutic class: VEGF (Vascular Endothelial Growth Factor) and Ang-2 (Angiopoietin-2) inhibitors |
Pharmacological class: Monoclonal Antibodies | Indications: Uses of Vabysmo 6mg Injection: 1. Diabetic macular edema (DME) 2. Wet age-related macular degeneration (AMD) 3. Retinal vein occlusion (RVO) 4. Myopic choroidal neovascularisation (mCNV) |
References
1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/761235s000lbl.pdf
2. Shirley M. Faricimab: First Approval. https://pubmed.ncbi.nlm.nih.gov/35474059/
3. Nair AA, Finn AP, Sternberg P Jr. Spotlight on Faricimab in the Treatment of Wet Age-Related Macular Degeneration: Design, Development and Place in Therapy. https://pubmed.ncbi.nlm.nih.gov/36199631/
4. Liberski S, Wichrowska M, Kocięcki J. Aflibercept versus Faricimab in the Treatment of Neovascular Age-Related Macular Degeneration and Diabetic Macular Edema: A Review. https://pubmed.ncbi.nlm.nih.gov/36012690/
5. https://www.ema.europa.eu/en/documents/product-information/vabysmo-epar-product-information_en.pdf
Disclaimer
MrMed’s primary intention is to ensure that its consumers get accurate and trustworthy information that is reviewed by experts. The contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
