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Velcade 1mg Injection
Last updated on 07 Sep 2026 | 01:11 PM (IST)
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Introduction
Velcade 1mg Injection is a chemotherapy medication that belongs to the class of medicines called proteasome inhibitors. It contains the active ingredient Bortezomib and is used in the treatment of blood cancers. Many patients often ask, Is Velcade 1mg chemotherapy?, and the answer is yes, as it works by blocking cancer cell growth and survival. It is primarily prescribed for conditions such as multiple myeloma and mantle cell lymphoma. In fact, Velcade 1mg uses in Multiple Myeloma are well established, as it helps control the growth of abnormal plasma cells in the bone marrow. Mantle cell lymphoma is a less common cancer that affects the lymph nodes, and treatment plans may include specific regimens such as Velcade 1mg for Mantle Cell Lymphoma, which are determined by the doctor based on the patient’s condition.
This medication is often used along with other chemotherapy drugs like pegylated liposomal doxorubicin, rituximab, cyclophosphamide, doxorubicin, dexamethasone, prednisolone, or thalidomide, especially in patients who have not started treatment and are not eligible for a stem cell transplant. Patients should always consult their healthcare provider regarding practical details such as Velcade 1mg injection manufacturer, availability, and In, as these may vary based on the supplier and location. Some may also explore options to This, but it should only be done through authorised and trusted pharmacies with a valid prescription.
The common side effects associated with this injection include pneumonia, loss of appetite, tingling or burning sensation in the skin, nausea, vomiting, diarrhoea, mouth ulcers, constipation, muscle and bone pain, hair loss, fever, infections, itching, redness, dehydration, and other stomach-related issues. Inform your doctor if these side effects persist or worsen. In some cases, your doctor may suggest a Velcade 1mg injection substitute if the treatment is not well tolerated.
Uses
Treatment of multiple myeloma and mantle cell lymphoma.
How Velcade 1mg Injection works
Velcade 1mg Injection Injection works by exerting a toxic effect on cancer cells. It inhibits the 26S proteasome and blocks a major cell signaling pathway. This inhibition of the signaling pathway makes the cancer cells sensitive to chemotherapy. This medicine also enhances the build-up of a protein and minimizes cancer cell growth and multiplication.
Interaction of Velcade 1mg Injection with other drugs
Inform your doctor about any prescribed medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products that you are taking or have taken before the treatment. Certain medications may interact with Velcade 1mg Injection and may cause undesirable side effects.
Storage Conditions
Store unopened vials in the refrigerator (2 °C – 8 °C) and protect them from light.
Keep this medicine out of sight and reach of children.
How to use Velcade 1mg Injection
Velcade 1mg Injection is administered intravenously in your vein or subcutaneously under the skin. This injection should be given by a qualified healthcare professional experienced in the use of cytotoxic medications. Do not self-administer.
Safety Advice
Breast Feeding
Velcade 1mg Injection is unsafe to use during breastfeeding. Please discuss with your physician when it is safe to restart breastfeeding after this treatment.
Alcohol
It is unsafe to consume alcohol with this medication. Velcade 1mg Injection may cause excessive drowsiness with alcohol. Please consult your doctor for more advice.
Liver
Inform your physician before starting this treatment if you have Hepatitis infection or liver disease. Your physician will monitor your liver functions regularly.
Lungs
It is unknown whether Velcade 1mg Injection can be given to lung failure patients. Please consult your physician if you have any lung diseases.
Driving
Avoid driving or using machinery if you experience side effects like fainting, dizziness, tiredness, or blurred vision.
Pregnancy
Velcade 1mg Injection is unsafe to use during pregnancy unless clearly necessary. Both women of childbearing potential and men must use an effective contraception method during and three months after treatment.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Velcade 1mg side effects are
Serious
Muscle cramps
Confusion, visual disturbances, seizures, and headache
Breathlessness
Swelling of feet
Changes in heartbeat
High blood pressure
Fainting and tiredness
Cough and chest tightness
Common
Pneumonia
Loss of appetite
Sensitivity, tingling and burning sensation of the skin
Nausea, vomiting, and diarrhea
Mouth ulcers
Constipation
Muscle and bone pain
Hair loss
Fever
Reduction in blood cell count
Reduced kidney function
Shivering
Infections
Itching and redness
Dehydration
Stomach problems
Difficulty sleeping, anxiety, mood swings, depressed mood
Expert Tips
Both men and women should use effective contraception during treatment and for at least three months after completing it.
Velcade 1mg Injection may reduce red blood cells, white blood cells, and platelets.
Regular blood tests are required before and during treatment to monitor blood cell counts.
Pregnant women should not handle this injection as it contains cytotoxic substances.
Use gloves and protective clothing while handling the injection to avoid skin contact.
FAQs
Q1.
What is Velcade 1mg Injection used for?
Velcade 1mg Injection is mainly indicated to treat mantle cell lymphoma and multiple myeloma.
Q2.
Can I drive while taking Velcade 1mg Injection?
Velcade 1mg Injection may cause dizziness, tiredness, fainting, or blurred vision. Hence, avoid driving and operating heavy machines while this Injection.
Q3.
How is Velcade 1mg Injection given?
Velcade 1mg Injection is administered intravenously in your vein or subcutaneously under the skin by a doctor in a medical facility.
Q4.
Is it safe to handle Velcade 1mg Injection while pregnant?
No, Pregnant women should not handle Velcade 1mg Injection as it contains cytotoxic agents. Using gloves and protective clothing is recommended to prevent skin contact.
Q5.
What class of chemo is Velcade 1mg Injection?
Velcade 1mg Injection is a targeted therapy that belongs to the class of medicines called proteasome inhibitors.
Q6.
Can I take Velcade 1mg Injection when I am pregnant?
Avoid taking Velcade 1mg Injection if you are pregnant, as it can cause harmful effects on the unborn baby. Females should use effective birth control methods during treatment and at least three months after treatment.
Q7.
I am suffering from a Hepatitis infection. Can I take Velcade 1mg Injection?
Velcade 1mg Injection should not be used in patients with hepatitis infection because they might have a repeated attack of hepatitis, which can be fatal. If you have a history of hepatitis B infection, your doctor will carefully check you for signs of active hepatitis B.
Fact Box
Molecule name | Bortezomib |
Therapeutic class | Antineoplastics agents |
Pharmacological class | Proteasome inhibitor |
Indications | 1. Multiple myeloma 2. Mantle cell lymphoma |
References
- STADA, Electronic Medicines Compendium (EMC), [Revised on Nov 2021] [Accessed on 30 Nov 2022], https://www.medicines.org.uk/emc/files/pil.10201.pdf
- Takeda Pharmaceuticals U.S.A., Inc., [Revised on Aug 2022] [Accessed on 30 Nov 2022], https://www.velcade.com/files/pdfs/VELCADE_PRESCRIBING_INFORMATION.pdf
- Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.
- KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.
- H.G. Watson, J.I.O. Craig, L.M. Manson, Blood disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 989-1056
Disclaimer
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Author Details
Written By
Dr. Bhairavi S
Pharm. D
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 07 Sep 2026 | 01:11 PM (IST)
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