X TRANT 140MG CAPSULE

Introduction:

X Trant 140mg Capsule consists of the active ingredient Estramustine used to treat advanced cancer of the prostate gland, where hormonal therapy is not beneficial. It belongs to the category of medicines called antimitotic agents that stabilizes microtubule formation. 

This medicine should not be taken along with calcium-containing products such as milk, cheese and specific remedies for indigestion. Most common side effects include enlargement of breast tissues, liver dysfunction, swelling, nausea and diarrhea.

Uses of X Trant 140mg Capsule:

• Treatment of prostate cancer.

How X Trant 140mg Capsule Works:

Microtubules are essential components that play a vital role in cell division, signaling and shape, which makes it an attractive target for anticancer agents. X Trant 140mg Capsule gets concentrated in the prostate, binds to β-tubulin and interferes with the organization of microtubules and arrests cell multiplication. This leads to disruption of microtubule-associated proteins, inhibition of tumour cell growth and development.

Interaction with other drugs:

Inform your physician about any medications you are taking or have taken before the treatment.

More Information:

Store below 25˚C. 

References:

1. Pfizer Limited, Electronic Medicines Compendium (EMC), [Revised on Oct 2020] [Accessed on 21st May 2021] https://www.medicines.org.uk/emc/files/pil.1082.pdf
2. Christopher J. Hoimes, Antimicrotubule Agents, DeVita, Hellman, and Rosenberg’s Cancer Principles & Practice of Oncology, 11th edition, 2019, 571-585
3. Jaime E. Anderson, Andrea S. Dickens, Katherine Tipton Patel, Neoplastic Disorders and Their Treatment: General Principles, Applied Therapeutics: The Clinical Use of Drugs, 11th Edition, 2018, 1945-1967.
4. KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.

How to use X Trant 140mg Capsule:

Always take X Trant 140mg Capsule as directed by your physician. Do not take this medicine along with milk or milk products such as tea or coffee.     

Safety Advice:

Liver: 

Inform your physician before taking this medicine if you have liver problems.

Kidney:

Inform your physician before taking this medicine if you have kidney problems.

Allergies:

Inform your physician right away if you have allergic reactions to Estramustine or its ingredients

Others:

• Inform your physician if you have stomach or intestinal ulcer, heart disease
• Inform your physician if you have problems with blood clots or fluid retention.
• Consult your physician before starting this treatment if you have diabetes, high BP, stroke, breathing trouble, epilepsy, migraine or problems with bone marrow.
• Ensure that your physician regularly tests your blood, liver function and the calcium levels in your blood.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious:

• Allergic reactions such as wheezing, breathing difficulty, swelling of eyelids, face, lips.
• Rashes or itching that affects the whole body
• Chest pain

Common:

• Nausea, vomiting, diarrhea
• Abnormal liver function
• Low WBC, RBC and platelet levels in blood
• Enlargement of male breast tissue
• Fluid build-up in the body that causes swelling of ankles and legs.
• Headache
• Tiredness
• Heart attack
• Blood clots in blood vessels