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  3. Zexipag 200mcg Tablet
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Zexipag 200mcg Tablet

Prescription Required
selexipag
Written By:Ishwarya R.M.Sc. Reviewed By:Dr. Tejashwin AdigaMBBS

Last updated on 31 Mar 2026 | 09:30 AM (IST)

₹741

MRP: ₹866.25

(You Save ₹125.25)

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Zexipag 200mcg Tablet


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SELEXIPAG

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Zexipag 200mcg Tablet
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₹741

MRP: ₹866.25

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10 Tablet(...

10 Tablet(s) In A Strip

₹ 74.1/Unit

10 TABLET(s) IN A STRIP


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Prescription Required

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SELEXIPAG

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Introduction to Zexipag 200mcg Tablet

Zexipag 200mcg Tablet is a pulmonary vasodilator medication that belongs to a class of drugs called prostacyclin receptor agonists containing the active ingredient Selexipag. It is used to treat pulmonary arterial hypertension (PAH) to improve exercise capacity and delay disease progression. Pulmonary arterial hypertension is a serious and rare medical condition caused by high blood pressure in the arteries that supply the lungs. It primarily affects the small blood vessels (arteries) in the lungs, leading to their narrowing and increased resistance to blood flow.

This drug is contraindicated in individuals with known hypersensitivity or allergy to it or its component. It is also contraindicated if you have certain heart conditions such as severe coronary heart disease, unstable angina, recent heart attack, decompensated cardiac failure, severe irregular heartbeat, or certain heart valve defects. Also, if you have had a stroke within the last three months or any other event that reduces blood supply to the brain or are taking gemfibrozil (a medication used to lower lipid levels), this drug should not be taken.

If you have issues with your thyroid gland, it is necessary to inform your physician. Thyroid problems can impact the treatment plan, and your doctor will consider the potential effects of this drug on your condition. This drug is contraindicated during pregnancy because it can harm a developing fetus, and breastfeeding is not recommended in patients taking Zexipag 200mcg Tablet because it is unknown whether the medicine passes into the breast milk and harms your baby. This drug is metabolized and excreted by the kidneys, so if you have severe kidney problems or are undergoing dialysis, your doctor needs to determine the appropriate dosage or prescribe an alternative medicine if necessary.

Uses of Zexipag 200mcg Tablet

  • Treatment of pulmonary arterial hypertension (PAH)

Therapeutic Effects of Zexipag 200mcg Tablet

Zexipag 200mcg Tablet works by activating the prostacyclin receptors in the blood vessels of the lungs. This activation leads to the relaxation and widening of the blood vessels, reducing the elevated blood pressure in the pulmonary arteries. By dilating the blood vessels, this drug improves blood flow and reduces the workload on the heart.

Interaction of Zexipag 200mcg Tablet with other drugs

Inform your physician about all your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Zexipag 200mcg Tablet and reduce effectiveness by causing undesirable side effects.

More Information about Zexipag 200mcg Tablet

  • Store Zexipag 200mcg Tablet below (25°C).
  • Protect from light and moisture.

How to consume Zexipag 200mcg Tablet

Take the Zexipag 200mcg Tablet as advised by your physician. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.

Safety Advice for Zexipag 200mcg Tablet

Breast Feeding-unsafe

Breast Feeding

Unsafe

Breastfeeding is not recommended in patients taking Zexipag 200mcg Tablet because it is unknown whether the medicine passes into the breast milk and harms your baby.

Alcohol-Consult your doctor

Alcohol

Consult Your Doctor

It is unknown whether consuming alcohol while taking a Zexipag 200mcg Tablet is safe. Please speak with your physician.

Liver-Consult your doctor

Liver

Consult Your Doctor

Inform your doctor if you have liver disease because the Zexipag 200mcg Tablet should be used cautiously with a liver condition.

Lungs-Consult your doctor

Lungs

Consult Your Doctor

Zexipag 200mcg Tablet is safe for patients with lung problems. Consult your doctor for more advice.

Driving-unsafe

Driving

Unsafe

Some side effects of Zexipag 200mcg Tablet may cause headache and low blood pressure. It impairs your ability to drive or operate machinery safely. It is unsafe to consume this drug.

Pregnancy-unsafe

Pregnancy

Unsafe

Zexipag 200mcg Tablet is not recommended during pregnancy or if there is a possibility of becoming pregnant. It is advised for women to use appropriate contraceptive measures to prevent pregnancy while using this medication.

Side Effects of Zexipag 200mcg Tablet

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious

  • Headache
  • Diarrhea
  • Reddening of face
  • Vomiting, nausea
  • Pain in the jaws, muscles, legs, or joints
  • Stuffy nose

Common

  • Weight loss
  • Stomach pain
  • Rashes
  • Hyperthyroidism
  • Reduced appetite

Word of Advice

Since this medication aims to reduce joint pain, swelling, and stiffness, it may take several weeks or months to experience the full benefits of Zexipag 200mcg Tablet, so be patient and continue taking it as doctor advice.

FAQs about Zexipag 200mcg Tablet

Q1.

Can I take the Zexipag 200mcg Tablet if I have a thyroid problem?

If you have issues with your thyroid gland, it is necessary to inform your physician. Thyroid problems can impact the treatment plan, and your doctor will consider the potential effects of this drug on your condition.

Q2.

Are there any medications that should not be taken with Zexipag 200mcg Tablet?

Yes, some medications can interact with Zexipag 200mcg Tablet. One example is gemfibrozil, a medication used to lower lipid levels in the blood. Gemfibrozil can increase the exposure to this drug and should not be taken concomitantly. It's important to inform your healthcare provider about all the medications, including over-the-counter drugs and supplements, that you are taking to avoid potential interactions.

Q3.

Do I need to follow any special diet while using the Zexipag 200mcg Tablet?

You can continue your regular diet unless or until your doctor advises you to recommend any dietary changes.

Fact Box of Zexipag 200mcg Tablet

Molecule name: Selexipag

Therapeutic class: Pulmonary vasodilator

Pharmacological class:  Prostacyclin receptor agonists

Indications: Treatment of pulmonary arterial hypertension (PAH)

References

  1. Janssen-Cilag Limited, Electronic medicines compendium (EMC), [Revised on June 2022] [ Accessed on 18th July 2023], https://www.medicines.org.uk/emc/files/pil.2163.pdf
  2. Actelion Pharmaceutical US, US Food and Drug Administration, [Revised on Dec 2017] [ Accessed on 18th July 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/207947s005lbl.pdf
  3. Olivier Sitbon et al.; Selexipag for the Treatment of Pulmonary Arterial Hypertension; The New England Journal of Medicine; Published on Dec 2015; Accessed on 18/07/2023; https://pubmed.ncbi.nlm.nih.gov/26699168/

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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Author Details
Ishwarya R.

Written By

Ishwarya R.

M.Sc.


Dr. Tejashwin Adiga

Reviewed By

Dr. Tejashwin Adiga

MBBS


Last updated : 31 Mar 2026 | 09:30 AM (IST)

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