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Zyloric 100mg Tablet

Prescription Required
allopurinol

19

MRP: 20.27

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10 TABLET(s) IN A STRIP

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Zyloric 100mg Tablet
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19

MRP: 20.27

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10 Tablet(s) In A Strip

10 Tablet(s) In A Strip

1.9/Unit
Prescription Required
Prescription Required

Salt Composition

ALLOPURINOL

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GLAXO SMITHKLINE PHARMACEUTICALS LTD

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Introduction to Zyloric 100mg Tablet

Zyloric 100mg Tablet is an anti-hyperuricemic drug in the category of xanthine oxidase inhibitors, containing the active ingredient Allopurinol. It is used to treat gout (a form of inflammatory arthritis caused by sudden and severe attacks of pain, tenderness, redness, and swelling in the joints, most commonly affecting the base of the big toe). This tablet is also used to treat chemotherapy-induced hyperuricemia. Some cancer treatments can cause an increase in uric acid levels, which may lead to kidney damage or gout. This medicine may be used with chemotherapy to prevent hyperuricemia and its associated complications.

This drug is contraindicated in individuals with known hypersensitivity or allergy to it or its component. Stop taking this tablet and contact your doctor immediately if you develop a rash or skin symptoms. Inform your doctor of any heart, thyroid, kidney, or liver disease. Your physician may prescribe you a low dose and perform regular blood tests. It is generally recommended to avoid using Zyloric 100mg Tablet during pregnancy unless it is necessary. Taking this drug while breastfeeding is unsafe because it may affect the child. Do not breastfeed while taking this medicine.

Uses of Zyloric 100mg Tablet

Zyloric 100mg Tablet is used to treat,

  • Gout
  • Chemotherapy-induced hyperuricemia

Therapeutic Effects of Zyloric 100mg Tablet

Zyloric 100mg Tablet works by inhibiting the enzyme xanthine oxidase, which converts purines into uric acid. By reducing uric acid production, this drug helps lower uric acid levels in the blood count and prevents the formation of urate crystals, which cause gout and kidney stones.

Interaction of Zyloric 100mg Tablet with other drugs

Inform your physician about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications, including capecitabine, cyclosporine, mercaptopurine, theophylline, and warfarin, may interact with Zyloric 100mg Tablet and cause undesirable side effects.

More Information about Zyloric 100mg Tablet

  • Keep out of sight and reach of pets and children
  • Store the Zyloric 100mg Tablet protected from light at a temperature not exceeding 25°C.

How to consume Zyloric 100mg Tablet

Take the Zyloric 100mg Tablet as advised by your physician. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.

Safety Advice for Zyloric 100mg Tablet

Breast Feeding-Consult your doctor

Breast Feeding

Consult Your Doctor

Taking Zyloric 100mg Tablet while breastfeeding may be unsafe because it may affect the child. Do not breastfeed while taking this medicine.

Alcohol-Consult your doctor

Alcohol

Consult Your Doctor

It is unknown whether consuming alcohol while taking a Zyloric 100mg Tablet is safe. Please speak with your physician.

Liver-unsafe

Liver

Unsafe

Inform your doctor if you have liver disease because the Zyloric 100mg Tablet should be used cautiously with a liver condition.

Lungs-Consult your doctor

Lungs

Consult Your Doctor

It is unknown whether Zyloric 100mg Tablet is safe for patients with lung problems. Inform your doctor if you have lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.

Driving-unsafe

Driving

Unsafe

Driving vehicles or operating machinery while taking Zyloric 100mg Tablet is unsafe because it may cause drowsiness and vision problems. 

Pregnancy-Consult your doctor

Pregnancy

Consult Your Doctor

Zyloric 100mg Tablets should be taken if it is necessary during pregnancy. Report to your doctor if you are pregnant, suspecting, or planning for the pregnancy before starting the treatment. 

Side Effects of Zyloric 100mg Tablet

Side Effects are unwanted symptoms caused by medicines. Although all medicines cause side effects, not everyone gets them.

Common

  • Skin Rash
  • Nausea
  • Vomiting
  • Diarrhea
  • Headache
  • Drowsiness

Word of Advice

Avoid driving and lifting heavy machinery if you feel tired or weak during this treatment. Certain activities or conditions that can trigger gout attacks, such as fasting, rapid weight loss, and stress, should also be avoided while taking Zyloric 100mg Tablet. Foods high in purines should be avoided, such as red meat, organ meats, and some seafood, which can increase uric acid levels and reduce the effectiveness of this drug. It is highly advised to avoid or limit the consumption of these foods while taking this tablet.

Drink plenty of water. Smoking leads to oxidative stress in the body, leading to increased uric acid levels. It is advised to avoid smoking or using tobacco products while undergoing treatment with this drug.

FAQs about Zyloric 100mg Tablet

Q1.

How does Zyloric 100mg Tablet help in treating gout?

Zyloric 100mg Tablet works by inhibiting the enzyme xanthine oxidase, which converts purines into uric acid. By reducing uric acid production, this drug helps lower uric acid levels in the blood count and prevents the formation of urate crystals, which cause gout and kidney stones.

Q2.

How do I take Zyloric 100mg Tablet?

Zyloric 100mg Tablet is taken orally in the form of tablets. The frequency and dosage of administration will depend on the individual's condition and the doctor's recommendation. It is taken once daily, with or after a meal, along with plenty of fluids.

Q3.

Are there any common side effects of Zyloric 100mg Tablet?

Common side effects of Zyloric 100mg Tablet may include skin rash, nausea, vomiting, diarrhea, drowsiness, and headache. These side effects are temporary and mild. If you experience a severe skin rash, allergic reactions, or other side effects, seeking medical attention is important.

Q4.

How long does Zyloric 100mg Tablet take to start working?

The full effect of Zyloric 100mg Tablet may take several weeks or even months to be noticeable. You must continue taking this tablet as your doctor prescribes, even if you do not experience immediate relief.

Q5.

Can Zyloric 100mg Tablet be used in children?

Zyloric 100mg Tablet is generally not recommended in children under 11 unless specifically prescribed by a pediatric specialist. Dosage adjustments may be required in pediatric patients.

Fact Box of Zyloric 100mg Tablet

Molecule Name: Allopurinol 

Therapeutic class:  Antihyperuricemic agents

Pharmacological class: Xanthine oxidase inhibitors

Indications: 

1. Gout

2.Chemotherapy-induced hyperuricemia

References

  1. Strides Pharma UK Limited, European Medicine Consortium (EMC), [Revised on April 2022], Available at: https://www.medicines.org.uk/emc/files/pil.14283.pdf [Accessed on 27th May 2023].

  2. Allopurinol - food and drug administration (FDA). [Revised on Feb 2022], Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/020298s012lbl.pdf [Accessed on 27th May 2023].

  3. Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Inflammation, Immunomodulation and Hematopoiesis, pharmacotherapy of gout, 12th edition, 2011, 996.

  4. KD Tripathi, Essentials of Medical Pharmacology, Antirheumatoid and antigout drugs, 7th edition, 2013, 213-217.

Disclaimer

MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.

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Author Details
Dr. B. Deiva

Written By

Dr. B. Deiva

Pharm D

Dr. Tejashwin Adiga

Reviewed By

Dr. Tejashwin Adiga

MBBS

Last updated : 04 Sep 2026 | 06:21 AM (IST)

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