This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
Atazanavir is an antiretroviral medication containing the active constituent atazanavir. Along with other antiretroviral medications, it is utilized to treat HIV-1 infection. The human immunodeficiency virus (HIV-1) targets and kills immune system cells; if left untreated, the body's capacity to fight diseases declines and results in death. Lactose can be found in this medicine. If you are intolerant to sweets, let your doctor know. Atazanavir received FDA approval on June 20, 2003, to treat HIV-1 infection in adults.
Mechanism of Action of undefined
The working of Atazanavir lies in its ability to suppress the replication of HIV. As a protease inhibitor, it blocks the activity of the HIV protease enzyme, preventing the production of mature, infectious viral particles.
By reducing the viral load and slowing down the progression of HIV infection, this antiviral medication helps to preserve immune function, increase CD4 cell counts, and reduce the risk of opportunistic infections. This therapeutic effect allows individuals with HIV to maintain a healthier immune system and improve their long-term outcomes.
Uses of undefined
Atazanavir is used to treat HIV -1 Infection.
undefined Drug administaration and Dosage available
Atazanavir Tablet is taken orally. The medication is taken once a day, either with or can be taken without food, as directed by your healthcare provider. Swallow the capsule or tablet whole without crushing or chewing it.
Warnings, Precautions and Side Effects of undefined
Atazanavir carries several important warnings. These include the risk of severe skin reactions such as Stevens-Johnson syndrome or toxic epidermal necrolysis, the potential for liver problems and pancreatitis, the occurrence of immune reconstitution syndrome, the possibility of QT prolongation and associated irregular heartbeat, kidney problems, the increased risk of diabetes and hyperglycemia, fat redistribution, the potential for hypersensitivity reactions, and the likelihood of drug interactions.
Precautions while taking atazanavir include regularly monitoring liver function. Close monitoring of kidney function is also recommended. Individuals with existing heart conditions or taking medications that prolong the QT interval should exercise caution. Blood sugar levels may need to be monitored, especially in individuals with diabetes. Any unusual skin reactions or signs of hypersensitivity should be promptly reported to a healthcare professional.
Atazanavir may cause various side effects. Common side effects include nausea, diarrhea, headache, rash, and abdominal pain or discomfort. Serious side effects can include severe skin reactions, liver problems, pancreatitis, and immune reconstitution syndrome.
Word Of Advice
It is crucial to prioritize safety when considering using Atazanavir or other medication. Avoid its use during breastfeeding to protect the developing fetus. Cautious should be taken in existing heart conditions or medications that prolong the QT interval. Regular monitoring of blood sugar levels is important for individuals with diabetes. By following these precautions and promptly seeking medical attention for any concerning symptoms, individuals can ensure this medication's safe and effective use and optimize their overall treatment experience.
Frequently Asked Question
- Bristol-Myers Squibb, US Food and Drug Administration, [ Revised date: OCT 2011], [ Accessed date: 17 May 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021567s026lbl.pdf
- Dr. Reddy, Electronics Medicine compendium, [ Revised date: NOV 2018], [ Accessed date: 17 My 2023], https://www.medicines.org.uk/emc/files/pil.10778.pdf
- Laurance Brunton, Bruce Chabner, Bjorn Knollman Goodman & Gilman’s, The Pharmacological Basics of Therapeutics, Antiretroviral agents and treatment of HIV infection, 12th Edition, 2011, Page: 1623-1660
The drug information on this page is different from medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.