This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Background and Date of Approval
Calcium citrate, Vitamin D3, Calcitriol, Magnesium, and Vitamin K2-7 work together to strengthen teeth and bones by improving calcium absorption, supporting bone mineralisation, and ensuring proper calcium distribution, helping to prevent bone loss and enhance overall skeletal health.
Mechanism of Action of undefined
The combination of Calcium citrate, Vitamin D3, Calcitriol, Magnesium, and Vitamin K2-7 works together to support bone health. Calcium citrate provides bioavailable calcium for bone strength, while Vitamin D3 enhances calcium absorption and bone mineralisation. Calcitriol, the active form of Vitamin D, regulates calcium and phosphate levels, promoting strong bones. Magnesium aids in the conversion of Vitamin D into its active form and supports bone structure. Finally, Vitamin K2-7 directs calcium to the bones, ensuring proper mineralisation and preventing calcium buildup in soft tissues. This combination works synergistically to maintain healthy bones and teeth.
Uses of undefined
The combination of Calcium citrate, Vitamin D3, Calcitriol, Magnesium, and Vitamin K2-7 is used to promote strong bones and teeth, enhance calcium absorption, and improve bone mineralisation. It helps prevent and treat conditions like osteoporosis, supports proper calcium metabolism, and ensures that calcium is properly utilised in the bones rather than in soft tissues. This combination also aids in maintaining bone density and preventing fractures.
undefined Drug administaration and Dosage available
The combination drug of Calcium citrate, Vitamin D3, Calcitriol, Magnesium, and Vitamin K2-7 is typically administered orally in the form of tablets or capsules. It is usually taken once or twice daily with food to enhance absorption, particularly for fat-soluble components like Vitamin D3 and Vitamin K2-7. The exact dosage and frequency depend on the specific formulation and the healthcare provider's recommendations.
Warnings, Precautions and Side Effects of undefined
Warnings
- Risk of hypercalcemia: Excessive calcium can cause kidney stones, abnormal heart rhythms, and soft tissue calcification.
- Kidney disease: Use with caution if you have kidney problems, as high calcium and magnesium can worsen kidney function.
- Vitamin D toxicity: Overuse can raise calcium levels, potentially damaging kidneys and bones.
- Magnesium overdose: It can lead to low blood pressure, irregular heartbeat, and muscle weakness, especially in those with kidney disease.
- Allergic reactions: Stop using if you experience rash, swelling, or difficulty breathing.
- Drug interactions: Consult your doctor if you take medications like diuretics, anticoagulants, or corticosteroids.
- Pregnancy and breast-feeding: Check with your healthcare provider before using during pregnancy or breastfeeding.
Precautions
When using the combination of Calcium citrate, Vitamin D3, Calcitriol, Magnesium, and Vitamin K2-7, monitor kidney function if you have kidney disease, as it can worsen the condition. Check calcium levels regularly to avoid hypercalcemia, and consult your doctor if you take medications like diuretics or anticoagulants. Consult your healthcare provider before using if you are pregnant or breastfeeding. Always follow the prescribed dosage to avoid Vitamin D toxicity.
Side Effects
Side effects are unwanted symptoms caused by medicines. Although all drugs can cause side effects, not everyone experiences them.
Common side effects of Calcium citrate, Vitamin D3, Calcitriol, Magnesium and Vitamin K2-7 are:
- Constipation
- Upset stomach or nausea
- Diarrhea
- Flatulence (gas)
- Headache
- Dry mouth
- Metallic taste
Serious side effects of Calcium citrate, Vitamin D3, Calcitriol, Magnesium and Vitamin K2-7 are:
- Hypercalcemia
- Hypermagnesemia
- Vitamin D toxicity
- Allergic reactions such as rash, swelling and difficulty breathing
Word Of Advice
When using the combination of Calcium citrate, Vitamin D3, Calcitriol, Magnesium, and Vitamin K2-7, follow the recommended dosage to avoid side effects like hypercalcemia or toxicity. Monitor your calcium and magnesium levels, especially if you have kidney disease. Consult your doctor before use if you're pregnant, breastfeeding, or taking other medications. Stay consistent with your supplement regimen to maximise the benefits for bone health.
Frequently Asked Question
References
1. Quesada Gómez JM, Blanch Rubió J, Díaz Curiel M, Díez Pérez A. Calcium citrate and vitamin D in the treatment of osteoporosis. https://pubmed.ncbi.nlm.nih.gov/21405146/
2. Peppone LJ, Hebl S, Purnell JQ, Reid ME, Rosier RN, Mustian KM, Palesh OG, Huston AJ, Ling MN, Morrow GR. The efficacy of calcitriol therapy in the management of bone loss and fractures: a qualitative review. https://pmc.ncbi.nlm.nih.gov/articles/PMC3063996/
3. https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional/
4. Jadhav N, Ajgaonkar S, Saha P, Gurav P, Pandey A, Basudkar V, Gada Y, Panda S, Jadhav S, Mehta D, Nair S. Molecular Pathways and Roles for Vitamin K2-7 as a Health-Beneficial Nutraceutical: Challenges and Opportunities. https://pmc.ncbi.nlm.nih.gov/articles/PMC9237441/
Disclaimer
The drug information on this page is not a substitute for medical advice. It is meant for educational purposes only. For further details, consult your doctor about your medical condition to know if you can receive this treatment.