This page contains brief details about the drug , it's indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Background and Date of Approval

Iron polysaccharide is an iron supplement primarily used to treat or prevent iron deficiency anaemia, a condition caused by insufficient iron levels in the body. This complex delivers elemental iron in a polysaccharide matrix, allowing for efficient absorption and minimal gastrointestinal side effects. It was approved by the U.S. Food and Drug Administration (FDA) for medical use to combat iron deficiency. 

Clinical trials demonstrated its efficacy in improving haemoglobin levels and replenishing iron stores, with fewer adverse effects compared to traditional iron salts. This molecule has become a preferred choice for patients who cannot tolerate other iron supplements.

Mechanism of Action of undefined

Iron polysaccharide is designed to release iron in a controlled manner, allowing the body to absorb it through the small intestine. Once absorbed, iron contributes to haemoglobin and myoglobin synthesis, which are essential for oxygen transport and storage in the body. Additionally, it supports various enzymatic reactions crucial for energy production and cellular function. The polysaccharide coating prevents the iron from reacting with stomach acids, reducing gastrointestinal irritation and enhancing tolerability.

Uses of undefined

Iron polysaccharide is FDA-approved for:

  • Treating iron deficiency anaemia.
  • Preventing iron deficiency in individuals at risk (e.g., pregnant women, children, and those with poor dietary intake).

undefined Drug administaration and Dosage available

This supplement is available in oral forms, including capsules, tablets, and liquid suspensions. Dosages vary based on age, gender, and medical conditions:

  • Adults: Typically 50-100 mg of elemental iron daily.
  • Children: Dosage determined by weight and age, under medical supervision.

It should be taken on an empty stomach or with food if stomach upset occurs.

Warnings, Precautions and Side Effects of undefined

Warnings

  • Drug Interactions: Avoid concurrent use with antacids, tetracyclines, and quinolone antibiotics as they may reduce absorption.
  • Allergic Reactions: Individuals with hypersensitivity to any components should avoid this supplement.
  • Medical Conditions: Contraindicated in conditions like hemochromatosis or hemosiderosis due to iron overload risks.

Precautions

When taking iron polysaccharides, it is important to follow the prescribed dosage and avoid self-adjusting. Excessive iron can lead to toxicity. Pregnant and breastfeeding women should consult a healthcare provider to ensure appropriate supplementation. The drug should be kept out of reach of children to prevent accidental ingestion, which can cause serious poisoning. Always report persistent side effects or unusual symptoms to your doctor promptly.

Side Effects

Common Side Effects:

  • Mild nausea
  • Constipation or diarrhoea
  • Dark stools
  • Stomach cramps

Serious Side Effects:

  • Severe abdominal pain
  • Vomiting with blood
  • Allergic reactions (rash, itching, swelling)

Word Of Advice

To maximise the benefits of iron polysaccharide, take it with vitamin C-rich foods or beverages like orange juice, which enhances iron absorption. Avoid taking it alongside tea, coffee, or dairy products, as these can inhibit absorption. Store the supplement in a cool, dry place and always follow your doctor’s instructions regarding dosage and duration of use.

Frequently Asked Question

Disclaimer

This content is for informational purposes only and should not replace professional medical advice. Always consult your healthcare provider for personalised recommendations.