Quick Summary
Cirrosam 400mg Tablet 15's
Last updated on 25 Apr 2026 | 06:28 AM (IST)
₹1574
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15 TABLET(s) IN A STRIP
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Introduction
Cirrosam 400mg Tablet 15's contains the active ingredient ademetionine. It is commonly used to treat intrahepatic cholestasis, a condition where bile flow from the liver is reduced. It is also prescribed for other liver conditions such as cirrhosis and alcoholic hepatitis, and may be used as part of treatment for major depressive disorder. This medicine works by supporting bile production, which helps in fat digestion and toxin removal, and it may also help reduce pain and inflammation in osteoarthritis by lowering inflammatory chemicals and supporting cartilage repair. Patients often enquire about the Cirrosam 400 mg 15's price in India, which may vary based on pharmacy and availability.
Cirrosam 400mg Tablet 15's should not be used by individuals who are allergic to ademetionine or any of the tablet’s components. It is not recommended for people with bipolar disorder, as it may trigger manic episodes. This medicine should be avoided during pregnancy and breastfeeding due to limited safety data. It may be harmful in patients with severe kidney impairment and is not advised for those with Parkinson’s disease or homocystinuria, as it may worsen symptoms. While generally considered safe for older adults, medical consultation is important before use. The medicine has not been well studied in children and should only be used if specifically prescribed by a doctor.
Doctors may discuss Cirrosam 400 mg Tablet 15's dosage and precautions based on the patient’s condition, liver function, and overall health. In some cases, alternative treatment options or Cirrosam 400 mg Tablet 15's substitutes may be considered depending on tolerance, response, or availability. Always follow medical advice closely and do not start or stop this medicine without consulting a healthcare professional.
Uses
Cirrosam 400 mg tablet 15's uses as follows:
Hepatoprotective
Antidepressant
Chondroprotective
Antioxidant
Nootropic
How Cirrosam 400mg Tablet 15's works
Cirrosam 400mg Tablet 15's works by donating methyl groups to other molecules, which is essential for many cellular functions, including DNA repair, gene expression, and protein synthesis. It is also a precursor to glutathione, a powerful antioxidant that protects cells from damage. Additionally, it is involved in the production of bile, which helps to digest fats and remove toxins from the body.
Interaction of Cirrosam 400mg Tablet 15's with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with the Cirrosam 400mg Tablet 15's reducing effectiveness by causing undesirable side effects.
Storage conditions
Store at room temperature, between 20°C to 25°C
Keep away from moisture, heat, and light.
It should not be frozen.
How to take Cirrosam 400mg Tablet 15's
Cirrosam 400mg Tablet 15's administered orally. Do not break or chew or crush this tablet. Follow the procedure mentioned by the doctor or pharmacist.
Safety Advices
Pregnancy
Cirrosam 400mg Tablet 15's has not been studied extensively in pregnant women, so it is best to avoid it during these times. It is important to consult with a healthcare provider to assess the individual situation.
Breast Feeding
It is important to consult with a healthcare provider before taking Cirrosam 400mg Tablet 15's as it has not been studied extensively in breastfeeding women.
Lungs
Consult your healthcare provider if you have a history of lung conditions before using the Cirrosam 400mg Tablet 15's.
Liver
If you have liver disorders, informing your healthcare provider before starting the Cirrosam 400mg Tablet 15's is important.
Alcohol
It is not safe alcohol while taking Cirrosam 400mg Tablet 15's, as alcohol can exacerbate certain side effects.
Driving
Cirrosam 400mg Tablet 15's is not known to impair cognitive or motor function. Therefore, it does not typically interfere with the ability to drive or operate machinery. If you experience these symptoms, consult your healthcare provider if you experience side effects.
Side Effects
Cirrosam 400mg Tablet 15's causes some side effects like all medications, although not everyone will experience them.
Serious
Allergic reactions
Mania or hypomania
Serotonin syndrome
Worsening liver disease
Common
Abdominal discomfort
Nausea and vomiting
Headache
Dizziness
Insomnia
Anxiety
Expert tips
Consult a healthcare provider before using Cirrosam 400mg Tablet 15's if you have bipolar disorder, Parkinson’s disease, or a history of mania.
Avoid using this medicine during pregnancy and breastfeeding, as its safety is not well established.
Use caution if you have underlying medical conditions, especially anxiety disorders or diabetes.
Children should use this medicine only under medical supervision.
Be aware of possible side effects such as stomach discomfort, dry mouth, headache, or mild insomnia.
Follow the recommended dosage strictly to reduce the risk of adverse effects.
Stop taking the medicine at least two weeks before any planned surgery, as it may affect the central nervous system.
Inform your doctor if you have a bleeding disorder or are taking medicines that increase bleeding risk before starting this treatment.
FAQs
Q1.
Are there any dietary restrictions to consider when taking Cirrosam 400mg Tablet 15's?
While there are no specific dietary restrictions while taking Cirrosam 400mg Tablet 15's, it is advisable to follow a balanced diet as recommended by a healthcare provider.
Q2.
What are the potential side effects of Cirrosam 400mg Tablet 15's?
Some common side effects of Cirrosam 400mg Tablet 15's may include gastrointestinal disturbances, dry mouth, headache, and mild insomnia. However, individual reactions may vary.
Q3.
Can Cirrosam 400mg Tablet 15's be used long-term?
The long-term use of Cirrosam 400mg Tablet 15's should be monitored by a healthcare provider, especially if it is used to manage chronic conditions. Regular check-ups and discussions with a healthcare provider can help assess the ongoing benefits and any potential risks associated with long-term use.
Fact Box
Molecule name | Ademetionine |
Therapeutic class | hepatoprotective agents |
Pharmacological class | Sulfur-containing amino acid derivative. |
Indications | 1. Hepatoprotective 2. Antidepressant 3. Chondroprotective 4. Antioxidant 5. Nootropic |
References
Abbott Laboratories, [Accessed on 25th Oct 2023], https://www.medicine.abbott/content/dam/bss/divisionalsites/epd/productpdf/Transmetil%20500mg.pdf
Mazen Noureddin et al., Early treatment efficacy of S-adenosylmethionine in patients with intrahepatic cholestasis: A systematic review;[Published on Feb 2020][Accessed on 25th Oct 2023] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061266/
S-adenosylmethionine; [Accessed on 25th Oct 2023]; http://accurateclinic.com/wp-content/uploads/2016/02/S-adenosylmethionine-University-of-Maryland-Medical-Center. pdf#2
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details
Written By
Dr. Vikas B S
Pharm D
Reviewed By
Dr. Abhishaanth Prabu
MBBS
Last updated : 25 Apr 2026 | 06:28 AM (IST)
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