• Supportive therapy for patients with chronic diseases
• Treatment of constipation in adults
• Reduce the symptoms of gastrointestinal problems
• Boost the immune system by restoring gut health
• Treatment of diarrhea
• Treatment of inflammatory bowel disease, peptic ulcer, and allergic diseases
• Prevention of cancer and related side effects
• Reduction of blood cholesterol, which is helpful in preventing obesity, diabetes, and other metabolic disorders

Refilac capsule contains pre-probiotics. Lactobacillus acidophilus, Bifidobacterium longum, and Streptococcus thermophilus are probiotics, while lactate is a prebiotic. Probiotics and prebiotics are used together to facilitate the growth of good bacteria in the gut. Lactitol decreases the intestine's pH and favors good bacteria growth while inhibiting Enterobacteriaceae. It acts as a laxative by increasing fecal volume. Streptococcus thermophilus has the potential to inhibit infection-causing microorganisms in the intestine and is beneficial to prevent or amend certain diseases. Bifidobacterium longum utilizes toxic compounds in the intestine as nutrients that favor its growth.

Inform your healthcare provider about all your medicines, including prescription, over-the-counter, nutritional, supplements, and herbal products. Certain medications interact with refilac capsules, reducing their effectiveness by causing undesirable side effects.

• Store refilac capsule below 2℃ - 8℃.
• Protect from light and excessive moisture.
• Keep the medicine out of reach of children and pets.

Take the refilac capsule as advised by your physician. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the capsule if your doctor advises you to stop.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Common

• Stomach cramps
• Loose stools
• Bloating
• Gas and flatulence

Inform the doctor about all the underlying medical conditions. Do not stop the medicine until your doctor advises. Notify your doctor if you experience any serious side effects. Your medical professional will inform you if you need any dose adjustments. Please do not take this medicine more than your physician prescribed, as it can cause some side effects. Seek immediate medical emergency if needed. Contact your doctor for more information.

1. Ramos‐Ramos et al., Proof‐of‐concept trial of the combination of lactitol with Bifidobacterium bifdum and Lactobacillus acidophilus for the eradication of intestinal OXA‐48‐producing Enterobacteriaceae; Accessed on 13/12/2023;  https://gutpathogens.biomedcentral.com/articles/10.1186/s13099-020-00354-9
2. Larry E Miller et al., Efficacy and tolerance of lactitol supplementation for adult constipation: a systematic review and meta-analysis; Published on Jul 2014; Accessed on 13/12/2023; https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4103919/
3. Rohit Sharma et al., Probiotic Efficacy and Potential of Streptococcus thermophilus modulating human health: A synoptic review, IOSR Journal of Pharmacy and Biological Sciences; Published on 03/09/2023; Accessed on 13/12/2023;  https://www.researchgate.net/publication/262416546
4. Markowiak P et al., Effects of Probiotics, Prebiotics, and Synbiotics on Human Health, Nutrients. 2017 Sep; 9(9): Published on 09/09/2023; Accessed on 13/12/2023;  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622781/
5. Elisavet Stavropoulou et al., Probiotics in Medicine: A Long Debate, Front. Immunol., Accessed on 13/12/2023; https://www.frontiersin.org/articles/10.3389/fimmu.2020.02192/full