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Report any side effects or concerns during Admatop 2.5mg Injection treatment to your healthcare provider promptly.
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Avoid grapefruit and its juice, as it can interfere with the drug’s absorption and cause serious side effects.
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Use effective birth control during treatment and for at least 2 weeks after the final dose if you are a woman of reproductive age.
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Discuss risks and benefits with your doctor if you are pregnant, planning pregnancy, or breastfeeding.
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Protect your skin from sunlight during treatment to avoid skin sensitivity or reactions.
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Adopt healthy lifestyle changes such as:
-
Quitting smoking
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Maintaining a healthy weight
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Eating a balanced diet
-
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Seek emotional support from family, friends, or support groups to help cope with cancer treatment.
Quick Summary
Admatop 2.5mg Injection
Written By:P. Thirumal ReddyB. Pharm Reviewed By:Dr. Tejashwin AdigaMBBS
Last updated on 31 Mar 2026 | 09:30 AM (IST)
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Substitutes
Topowin 2.5mg Injection
NELWIN LIFESCIE...
₹ 3750.00/injection
7% cheaper
Topotec 2.5mg Injection
UNITED BIOTECH ...
₹ 5055.00/injection
25% costlier


Introduction
Admatop 2.5mg Injection is an anti-cancer medicine that contains Topotecan. It is used to treat ovarian and lung cancers that have returned after chemotherapy, and also for advanced cervical cancer in combination with cisplatin when surgery or radiation is no longer effective. The Admatop dosage is based on body weight and overall health and is given as an injection by a healthcare professional. This medicine is not recommended for children. Patients should avoid grapefruit or grapefruit juice during treatment, as it can increase the absorption of the drug and raise the risk of side effects.
One of the common side effects of Admatop injection is neutropenia, a drop in white blood cells that can increase the risk of infection. Admatop neutropenia management irinotecan includes regular blood tests, dose adjustments, or supportive medications like growth factors. Doctors usually manage this through regular blood tests and supportive medication. If you experience fever, unusual bleeding, or signs of infection, inform your doctor right away. Side effects are generally manageable, and many patients respond well to treatment. If you’ve had an allergy to Admatop or its ingredients before, make sure to tell your doctor. The Admatop price may vary depending on location and supplier, so consult a certified oncology pharmacy for accurate cost details.
Uses
Admatop Uses are:
- Ovarian cancer
- Small cell lung cancer
- Advanced cervical cancer
How Admatop 2.5mg Injection works
Admatop 2.5mg Injection works by interfering with the normal function of DNA, which prevents cancer cells from dividing and growing. This helps to slow or stop the growth of cancer cells, which can lead to the regression of tumors and an improvement in cancer symptoms.
Interaction of Admatop 2.5mg Injection with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Admatop 2.5mg Injection and reduce effectiveness by causing undesirable side effects.
Storage conditions
- Store in a refrigerator at 2-8°C.
- Do not freeze.
- Protected from light.
- Keep it in its original packaging until it is ready to be used.
- Keep out of the reach of children and pets.
- Should be disposed of properly.
How to use Admatop 2.5mg Injection
Admatop 2.5mg Injection is typically administered by a healthcare provider as an intravenous (IV) infusion in a clinical setting. The dosage and frequency of infusions will vary depending on the patient's individual medical condition, age, weight, and other factors. You should not take a double dose to make up for the second dose.
Safety Advice for Admatop 2.5mg Injection
Breast Feeding
Consult Your Doctor
It is not clear whether Admatop 2.5mg Injection is excreted in human milk or not. So you should consult a doctor before taking this medication if you are a breastfeeding mother.
Alcohol
Unsafe
It is recommended to avoid consuming alcohol while taking Admatop 2.5mg Injection, as alcohol can increase the risk of certain side effects associated with the medication, such as stomach ulcers or gastrointestinal bleeding.
Liver
Unsafe
Admatop 2.5mg Injection is primarily metabolized in the liver, so inform your healthcare provider if you have any liver problems or diseases. This medication may also increase liver enzymes, which can be a sign of liver damage or inflammation. Patients taking this medication require regular blood tests to monitor liver function.
Lungs
Consult Your Doctor
Admatop 2.5mg Injection is used to treat small-cell lung cancer, which is a type of lung cancer that is often aggressive and difficult to treat. Patients with pre-existing lung conditions, such as chronic obstructive pulmonary disease (COPD) or asthma, should discuss the risks and benefits of treatment with their healthcare provider.
Driving
Unsafe
Patients receiving Admatop 2.5mg Injection should be advised to avoid driving or operating machinery if they experience side effects such as fatigue, dizziness, or blurred vision, impairing a patient's ability to drive or operate machinery safely.
Pregnancy
Unsafe
Admatop 2.5mg Injection is unsafe during pregnancy as it can cause fetal harm. It is recommended to avoid this medication during pregnancy.
Side Effects
Admatop 2.5 mg injection ovarian cancer side effects include
Serious:
- Bone marrow suppression (increased risk of infection, anemia, and bleeding)
- Gastrointestinal toxicity (diarrhea, vomiting, and dehydration)
- Lung toxicity (difficulty breathing, coughing, and chest pain)
- Neurological toxicity (numbness or tingling in the hands or feet, confusion, and seizures)
- Cardiac toxicity (changes in heart rate and blood pressure)
- Allergic reactions (swelling of the face or throat, difficulty breathing, and hives)
- Liver toxicity (yellowing of the skin or eyes, dark urine, and abdominal pain)
Common:
- Nausea
- Vomiting
- Diarrhea
- Fatigue
- Anemia
- Hair loss
- Decreased appetite
- Mouth sores
- Fever
- Headache
- Insomnia
- Dizziness
- Muscle weakness
- Back pain
- Difficulty breathing
Expert Tips
FAQs about Admatop 2.5mg Injection
Q1.
Can Admatop 2.5mg Injection be given to elderly patients?
Yes, Admatop 2.5mg Injection can be given to elderly patients. However, elderly patients may be at higher risk of certain side effects, such as bone marrow suppression and gastrointestinal toxicity. The dosage may need to be adjusted for elderly patients.
Q2.
How Admatop 2.5mg Injection will affect my blood?
Admatop 2.5mg Injection can affect your blood count by decreasing the number of white blood cells, red blood cells, and platelets in your blood. This can increase the risk of infections, anemia, and bleeding. Your healthcare provider will monitor your blood counts regularly during treatment and may adjust your dosage or delay treatment based on your blood count results.
Q3.
Can Admatop 2.5mg Injection cause nerve damage?
Admatop 2.5mg Injection can cause nerve damage, which may lead to symptoms such as tingling, numbness, or weakness in the hands and feet. Patients should notify their healthcare provider if they experience any new or worsening neurological symptoms.
Q4.
Can Admatop 2.5mg Injection cause fertility problems?
Admatop 2.5mg Injection may affect fertility in both men and women. Patients should discuss their options for preserving fertility with their healthcare provider before starting treatment.
Q5.
What can I do to manage gastrointestinal toxicity caused by Admatop 2.5mg Injection?
Your healthcare provider medications to help manage nausea, vomiting, and diarrhea caused by Admatop 2.5mg Injection. You can also try eating small, frequent meals and drinking plenty of fluids to help alleviate these symptoms.
Fact Box
|
Molecule name |
Topotecan |
|
Therapeutic class |
Anticancer |
|
Pharmacological class |
Antineoplastic |
|
Indications
|
1. Ovarian cancer 2. Small cell lung cancer 3. Advanced cervical cancer |
References
- Accord Healthcare Limited, Electronic Medicines Compendium (EMC), [Revised on Feb 2021] [Accessed on 24th April 2023], https://www.medicines.org.uk/emc/files/pil.4159.pdf
- Accord Ltd, US Food & Drug Administration, [Revised on Sep 2018] [Accessed on 24th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/020671s023lbl.pdf
- Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976
Disclaimer
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Author Details

Written By
P. Thirumal Reddy
B. Pharm

Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 31 Mar 2026 | 09:30 AM (IST)

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