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Adpaxil 300mg Injection
Last updated on 31 Mar 2026 | 09:29 AM (IST)
₹4519
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Introduction
Adpaxil 300mg Injection is a chemotherapy medication containing the active constituent paclitaxel. It is used to treat breast cancer, non-small cell lung cancer, ovarian cancer, and AIDS (Acquired Immuno-Deficiency Syndrome). Cancer is a condition in which cells are dividing and growing fast and in an uncontrolled manner. This medicine is not recommended for adolescents and children under the age of 18.
Adpaxil 300mg Injection may be given alone or in combination with other anticancer medicines. This chemotherapy medication is contraindicated in patients with severe liver problems, uncontrolled infection, and low white blood cell or platelet count. Talk to your doctor if you have heart disorders before taking this medicine. Adpaxil 300mg injection substitutes include Paclitaxel injection 300mg, depending on the prescribed treatment protocol.
Administration of this medicine may cause serious allergic reactions. Use effective birth control during the treatment and for at least six months after the last dose. Adpaxil 300mg Injection may be harmful to patients suffering from alcoholism as this medicine contains alcohol. Adpaxil 300mg injection price varies by retailer and location. You can buy Adpaxil 300mg online.
Uses
Adpaxil 300mg uses in the treatment of the following:
Ovarian cancer
Breast cancer
Non-small cell lung cancer
AIDS-related Kaposi’s sarcoma
How Adpaxil 300mg Injection Works
Adpaxil 300mg Injection inhibits the microtubule structures present in the cell. Microtubule structures help cancer cells to divide and multiply. Inhibition of these structures slows the growth of cancer cells.
Interaction of Adpaxil 300mg Injection with other drugs
Ketoconazole (Oral Route) Severe
Avoid combination if possible. Ketoconazole may increase paclitaxel levels in the blood, raising the risk of severe side effects such as nerve damage and bone marrow suppression.Ritonavir (Oral Route) Severe
Concurrent use can significantly increase paclitaxel exposure. If combination is unavoidable, close monitoring for toxicity is required.Clarithromycin (Oral Route) Moderate
This antibiotic may slow the breakdown of paclitaxel, increasing the risk of side effects like low blood counts and peripheral neuropathy.Erythromycin (Oral Route) Moderate
May increase paclitaxel concentration in the body. Doctors may monitor blood counts and adjust doses if needed.Phenytoin (Oral Route) Moderate
Phenytoin can reduce the effectiveness of paclitaxel by increasing its metabolism. Treatment response may need close evaluation.
Storage conditions
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Keep Adpaxil 300mg Injection out of sight and reach of children.
-
Do not store above 25°C.
-
Store in the original packaging to protect from moisture.
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Avoid direct sunlight
How to Use Adpaxil 300mg Injection
Adpaxil 300mg Injection will be administered to you intravenously by a healthcare professional or nurse in a healthcare setting. Do not self-administer this medication. For Adpaxil 300mg dosage adjustments or any concerns, please consult your healthcare provider.
Safety Advices
Pregnancy
Adpaxil 300mg Injection can harm your unborn baby. Tell your doctor if you are pregnant or planning to get pregnant before taking Adpaxil 300mg Injection.
Breast Feeding
Stop breastfeeding during the treatment with Adpaxil 300mg Injection. Consult your doctor for potential risks.
Lungs
It is unknown whether Adpaxil 300mg Injection can be given to patients with lung disorders. Please consult your physician for more advice.
Liver
It is contraindicated in patients with severe liver disorders. Inform your doctor if you have any liver disorders before taking Adpaxil 300mg Injection.
Alcohol
It is unsafe to consume alcohol with Adpaxil 300mg Injection.
Driving
The alcohol present in Adpaxil 300mg Injection may affect your ability to drive. Avoid driving if you feel unwell.
Side Effects
Adpaxil injection side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious side effects of Adpaxil 300mg Injection are:
Serious allergic reactions (rash, swelling of face, lips, throat, or tongue, trouble breathing, and swallowing)
Severe diarrhoea
Severe stomach pain
Common side effects of Adpaxil 300mg Injection are:
Anemia, feeling tired
Hair loss
Burning, tingling, or numbness in your feet or hands
Muscle and joint pain
Vomiting, nausea
Mouth or lip sores
Infections
Swelling of hands, feet, and face
Bleeding
Irritation at the injection site
Expert Tips
-
Inform your doctor if you are allergic to this medicine or have a history of liver problems, heart conditions, or if you are taking other medications for different health conditions.
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Your liver function, blood pressure, and blood count should be regularly monitored during treatment.
-
Do not take this medication if you are pregnant, planning to become pregnant, or breastfeeding, as it may harm the baby.
-
Avoid driving or operating heavy machinery after taking this medicine, as it may reduce your concentration and alertness.
FAQs
Q1.
Can Adpaxil 300mg Injection cause hair loss?
Yes, the common side effect of this medication is hair loss and inform the doctor if there is excessive hair loss.
Q2.
Can I take Adpaxil 300mg Injection during pregnancy?
It is unsafe to take this medication during pregnancy as it causes harmful effects on the developing baby. Inform the doctor if the patient is planning for pregnancy before starting this medication.
Q3.
What are the side effects of Adpaxil 300mg Injection?
The common side effects of this medication are anaemia, hair loss, numbness in feet or hands, muscle pain, nausea, vomiting, infections, swelling, bleeding, irritation on the injection site, and low blood pressure.
Q4.
What is the Working mechanism of Adpaxil 300mg Injection?
Adpaxil 300mg Injection works by interfering with the microtubule structures that cancer cells need to divide and grow. By disrupting this process it helps slow down the growth and spread of cancer cells.
Q5.
Can I take Adpaxil 300mg Injection while driving?
It is unsafe to use this medication while driving because it can cause dizziness, lack of concentration and alertness.
Q6.
Does Adpaxil 300mg Injection cause liver problems?
Yes, this medication is contraindicated in patients with severe liver disorders. Inform the doctor before starting this medication.
Fact Box
|
Molecule name |
Paclitaxel |
|
Pharmacological class |
Anti-Microtubular Agents |
|
Therapeutic class |
Anti-Neoplastics |
|
Indications |
1. Ovarian cancer 2. Breast cancer 3. Non-small cell lung cancer 4. AIDS-related Kaposi’s sarcoma |
References
1. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1707 - 1709.
2. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 865.
3. Hospira UK Limited, Electronic medicines compendium (emc), [ Revised on March 2020] [ Accessed on 22nd June 2021], https://www.medicines.org.uk/emc/files/pil.3891.pdf
4. Bristol-Myers Squibb Company, US Food and Drug Administration, [ Revised on April 2011] [ Accessed on 22nd June 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020262s049lbl.pdf
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details

Written By
Dr. Vikas B S
Pharm D

Reviewed By
Dr. Abhishaanth Prabu
MBBS
Last updated : 31 Mar 2026 | 09:29 AM (IST)

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