• Adjunct to Dexamethasone for treating newly diagnosed multiple myeloma.
• Treatment of moderate to severe leprosy.
• Prevention of recurrence of skin lesions in leprosy.

Adthal 50mg Capsule reduces inflammation and regulates the immune system. It works by enabling the body’s immune system and attacking the cancer cells. It inhibits tumor necrosis factor-alpha, increases the production of interleukin-10 and interacts with the T-cells to generate an immune response. It halts the growth of blood vessels in cancer cells and arrests their development.

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Adthal 50mg Capsule and can cause undesirable side effects.

• Do not store above 30°C
• Keep out of sight and reach of pets and children.
• Do not freeze the medicine.
• Always check the expiry date before consuming it.

Take the Adthal 50mg Capsule as your physician advises. Take medicine at a fixed time. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious

• Nerve damage
• Decreased blood pressure
• Low WBC count
• Slow heartbeat
• Serious allergic reactions
• Tumor lysis syndrome
• Sudden pain in the chest or difficulty breathing
• Pain and swelling of legs
• Bleeding or bruising without injury

 Common

• Sleepiness
• Rashes
• Headache
• Dizziness
• Impotence
• Decreased energy or strength
• Pain
• Tiredness
• Low calcium and blood count levels
• Swelling of hands and feet
• Constipation
• Numbness or tingling
• Nausea and reduced appetite
• Anxiety, depression, confusion and mood swings
• Fever
• Weight loss or weight gain
• Indigestion, vomiting and dry mouth
• Muscle cramps
• Blurred vision
• Chest infection, lung disease
• Ear problems
• Kidney damage

Talk to your physician if you have had a heart attack, blood disorders, high BP or high cholesterol. Inform your physician before starting treatment, seizures, skin reactions or severe infections. Inform your physician if you smoke or drink alcohol. Before starting the treatment, inform your doctor about all the underlying medical conditions. Do not stop the medicine until your doctor advises. Do not double-dose the medicine to make up for a forgotten dose. Notify your doctor if you experience any serious side effects. Contact your doctor for more information.

1. Celgene Europe B.V, Electronic Medicines Compendium (EMC), [Revised on Aug 2021] [Accessed on 19th August 2023], https://www.medicines.org.uk/emc/files/pil.6317.pdf

2. Celgene Corporation, US Food and Drug Administration, [Revised on Jun 2019] [Accessed on 19th August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/020785s067lbl.pdf

3. Douglas F. Lake and Adrienne D. Briggs, Immunopharmacology, Lange’s Basic & Clinical Pharmacology, 14th Edition, 2018, 977-1002.

4. D.H. Dockrell, S. Sundar, B.J. Angus, R.P. Hobson, Infectious Disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 293-386.