Afzanna uses are in treat the following conditions: 

• Non-small cell lung cancer (NSCLC)

The therapeutic effect of Afzanna 40mg Tablet is primarily related to its ability to inhibit the activity of certain proteins in cancer cells, specifically the epidermal growth factor receptor (EGFR) family of proteins. These proteins play a key role in promoting the growth and spread of cancer cells, and by inhibiting their activity, it can help to slow or stop the progression of cancer.

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Afzanna 40mg Tablet and reduce effectiveness by causing undesirable side effects.

• Afzanna 40mg Tablet should be stored at room temperature, between 40°C to 25°C (68°F to 77°F).
• Protected from light.
• Keep it in its original packaging until it is ready to be used.
• Keep out of the reach of children and pets.
• Should be disposed of properly.

Afzanna 40mg Tablet is an oral medication that is usually taken once a day, at approximately the same time each day, with or without food. It should be taken as prescribed by a doctor. These capsules should be swallowed whole with a glass of water. They should not be crushed, chewed, or opened, as this can affect how the medication is absorbed and decrease its effectiveness. You should not take a double dose to make up for the second dose.

Like all medications, Afzanna 40mg Tablet can cause side effects, although not everyone who takes it will experience them. Afzanna 40mg side effects

Serious:

• Interstitial lung disease (ILD)
• Severe diarrhea or dehydration
• Liver problems
• Eye problems, such as corneal erosion or ulceration
• Hemorrhage or bleeding problems
• Kidney problems
• Cardiac problems 

Common:

• Diarrhea
• Mouth sores
• Acne or skin rash
• Nausea and vomiting
• Fatigue
• Loss of appetite
• Abdominal pain
• Nail changes, such as nail bed infections or inflammation
• Dry skin or itching
• Eye irritation or dryness
• Respiratory infections

• Follow all instructions and dosing recommendations provided by your healthcare provider.

• Do not take more or less medication than prescribed.

• Report any new or worsening symptoms immediately, especially if they affect your lungs, eyes, skin, liver, kidneys, heart, or cause bleeding.

• Stay well-hydrated during treatment.

• Report any signs of dehydration (such as dry mouth, dizziness, or decreased urination) to your healthcare provider immediately, especially if severe diarrhea occurs.

• Women should avoid pregnancy and breastfeeding while on this medication.

• Reproductive-age women must use effective birth control during treatment and for at least two weeks after the last dose.

1. Boehringer Ingelheim Pharmaceuticals, Inc, US Food and Drug Administration, [ Revised on Jan 2018] [ Accessed on 21st April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/4018/401292s014lbl.pdf

2. Boehringer Ingelheim International GmbH, Electronic Medicines Compendium (emc), [ Revised on Sept 2020] [ Accessed on 21st April 2023], https://www.medicines.org.uk/emc/files/pil.5147.pdf

3. Helga Wecker, Cornelius F Waller; Afatinib; Recent Results in Cancer Research 2018; https://pubmed.ncbi.nlm.nih.gov/40069769/