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ALPHALAN 5MG TABLET

Prescription Required

Salt Composition : Melphalan

Manufacturer : NATCO PHARMA LTD

Origin of Medicine : India

MRP: â‚ą3725
Price : â‚ą3167
You Save : â‚ą558 (15%)

25 Tablet(s) In A Bottle


Introduction to Alphalan 5mg Tablet

Alphalan 5mg tablet contains the active constituent Melphalan. It is an anticancer agent that belongs to the class of medications called alkylating agents. It is used to treat multiple myeloma (a type of cancer of the bone marrow). It is also used to treat advanced breast and ovarian cancer. It is also indicated to treat polycythemia vera ( a disease that increases the number of red cells in your blood. This makes the blood thicken and causes blood clots). It works by reducing the number of abnormal cells your body makes.  

Do not take Alphalan 5mg tablet if you are allergic to melphalan or any of the other ingredients. Inform your physician if you have had radiotherapy or cancer chemotherapy recently or have a kidney problem. Do not take this medicine if you are pregnant or planning for pregnancy. Inform your doctor if you have been vaccinated recently or planning to take any vaccination. Report to your physician immediately if you have a rash, lumps or hives on the skin, swollen face, eyelids, or lips, sudden wheeziness, and chest tightness after consuming the medicine.


Uses of Alphalan 5mg Tablet

  • Multiple myeloma
  • Advanced breast cancer
  • Advanced ovarian cancer
  • Polycythemia vera

Therapeutic Effects of Alphalan 5mg Tablet

Alphalan 5mg tablet is an alkylating agent. It exerts its cytotoxic action primarily due to the cross-linking of strands of DNA and RNA, as well as the inhibition of protein synthesis. It works by stopping or slowing the growth of cancer cells in your body.


Interaction of Alphalan 5mg Tablet with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional and vitamin supplements, and herbal products. Certain medications interact with Alphalan 5mg tablet and reduce its effectiveness by causing undesirable side effects. 


More Information about Alphalan 5mg Tablet

  • Store in a refrigerator, 2° to 8°C
  • Protect the medicine from light and excessive moisture.
  • Keep the medicine out of reach of children and pets
  • If you forgot to take the tablet, simply take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose.

How to consume Alphalan 5mg Tablet

Your doctor will decide the dose and duration of Alphalan 5mg tablet based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time, with or without food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with water. 


Safety Advices for Alphalan 5mg Tablet

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Pregnancy

  

Do not take Alphalan 5mg tablet if you are pregnant because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment. Use effective contraception during the treatment. 

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Breast Feeding

  

Breastfeeding is not recommended in patients taking Alphalan 5mg tablet because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment. 

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Lungs

  

It is unknown whether Alphalan 5mg tablet can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

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Liver

  

There is limited information available on the use of Alphalan 5mg tablet in patients with liver disease. Please consult your doctor if you have any liver diseases.

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Alcohol

  

It is not known whether it is safe to consume alcohol with Alphalan 5mg tablet. Please consult your doctor.

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Driving

  

It is not known whether Alphalan 5mg tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.


Side Effects of Alphalan 5mg Tablet

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. 

 Common 

  • Decreased blood cell count
  • Nausea, vomiting, diarrhea
  • Mouth ulcers
  • Hair loss

Serious  

  • Cardiac arrest
  • Liver inflammation
  • Hypersensitivity skin reactions
  • Acute renal failure
  • Lung inflammation

Word of Advice

This medicine may cause changes in your blood levels. Your doctor may advise you to take certain blood tests during the treatment to monitor any unwanted side effects. Do not take an extra dose to make up for a missed dose. This medicine could cause infertility. Talk with your doctor before using this medicine if you are planning for pregnancy. This medicine may you to bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. 


FAQs

Q 1. Can a patient with kidney problems take Alphalan 5mg tablet?

Alphalan 5mg tablet should be cautiously taken if you have any kidney problems. Dose adjustments are necessary for patients with kidney diseases. Inform your doctor if you are on dialysis and have any kidney disorders.

Q 2. Does Alphalan 5mg tablet weaken the immune system?

The medicine can suppress your immune system and increase your chances of getting infections. Take precautions to prevent illness and injury.

Q 3. What if I overdose or take two doses of Alphalan 5mg tablet?

If you unknowingly overdosed or took two doses of Alphalan 5mg tablet, immediately inform your healthcare professional and seek medical advice.

Q 4. Should Alphalan 5mg tablet be taken with or without food?

Alphalan 5mg tablet comes as a tablet to take by mouth. It is usually taken on an empty stomach once a day. Your doctor will tell you how to take the medicine.

Q 5. Does Alphalan 5mg tablet cause hair loss?

Thinning or loss of your hair will usually start within two to four weeks of your first dose of Alphalan 5mg tablet. You may also have thinning or loss of eyelashes, eyebrows, and other body hair. Consult your doctor if you have excessive hair loss.


Fact Box of Alphalan 5mg Tablet

Molecule name: Melphalan 

Therapeutic class:  Antineoplastics

Pharmacological class: Alkylating agents 

Indications: 

  1. Multiple myeloma 
  2. Advanced breast cancer 
  3. Advanced ovarian cancer 
  4. Polycythemia vera 

References

  1. Melphalan 2 mg Tablets - Summary of Product Characteristics (SmPC) - (emc) www.medicines.org.uk. [revised on 2022] [cited 2023 Apr 7]. Available from: https://www.medicines.org.uk/emc/product/3806/smpc
  2. ALKERAN ® 2 - melphalan [revised on 2021] [cited 2023 Apr 7]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2003/14691slr024_alkeran_lbl.pdf
  3. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 860.

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