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Alphanine 500IU Injection
Salt Composition : Factor Ix
Manufacturer : GRIFOLS
Origin of Medicine : India
Introduction to Alphanine 500iu Injection
Alphanine 500IU Injection contains active components such as factor IX. In some cases, individuals with hemophilia A (caused by a deficiency of factor VIII) may develop inhibitors (antibodies) against factor VIII, making standard treatment less effective. In such situations, it may be considered as an alternative. It can be used before, during, and after surgery to prevent excessive bleeding. Some people with hemophilia B may receive it as a preventive measure to maintain a certain level of this in their bloodstream, reducing the risk of spontaneous bleeding episodes, particularly in joints and muscles. It may be administered following traumatic injuries or accidents to prevent or control bleeding. In rare cases, it may be considered for treating other bleeding disorders or conditions that involve a deficiency, such as acquired hemophilia.
If a person has a known allergy or hypersensitivity to Alphanine 500IU Injection or any components of this product, it is a contraindication to its use. It is inappropriate for individuals with DIC, a complex bleeding disorder characterized by abnormal clotting and bleeding. People with severe liver disease may not respond well to it, and the risks and benefits should be carefully weighed. While it is commonly used in pediatric patients with hemophilia B, the dosage and administration should be carefully adjusted based on age and weight, and the treatment should be closely monitored. Alphanine 500IU Injection replacement therapy can be safe and effective for older adults with hemophilia B. However, dosing and treatment plans may need to be adjusted based on individual health and medical history.
Uses of Alphanine 500iu Injection
Alphanine 500IU Injection is used in the following:
- Treatment of hemophilia B
- Prophylactic treatment
- Management of bleeding episodes
- Surgical procedures
- Trauma and injuries
- Alternative treatment for hemophilia A with inhibitors
- Other bleeding disorders
- Pediatric hemophilia B
Therapeutic Effects of Alphanine 500iu Injection
Once administered, the infused form Alphanine 500IU Injection, it mixes with the patient's blood, becoming available to participate in the coagulation cascade. In the event of an injury or bleeding episode, it helps initiate and accelerate the formation of a stable blood clot by activating other coagulation factors, ultimately leading to the cessation of bleeding.
Interaction of Alphanine 500iu Injection with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Alphanine 500IU Injection , reducing effectiveness by causing undesirable side effects.
More Information about Alphanine 500iu Injection
- Stored at room temperature from 20°C to 25°C.
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Alphanine 500iu Injection
Alphanine 500IU Injection replacement therapy can be administered through intravenous (IV) infusion or intravenous injection. The choice of administration route depends on the specific Alphanine 500IU Injection product, the patient's age, the severity of hemophilia B, and individual preferences.
Safety Advices for Alphanine 500iu Injection
The use of Alphanine 500IU Injection therapy during pregnancy should be discussed with a healthcare provider. The safety and potential risks to the developing fetus should be carefully considered, and treatment options should be weighed.
The safety of Alphanine 500IU Injection therapy during breastfeeding should be discussed with a healthcare provider. Considerations should include the impact on the nursing infant and the treatment's potential risks and benefits.
If you have a lung problem, consult a healthcare provider before taking Alphanine 500IU Injection
Individuals with severe liver disease should consult their healthcare provider before using Alphanine 500IU Injection.
Excessive alcohol consumption can lead to side effects, so it is not safe to consume alcohol if you are using Alphanine 500IU Injection.
Individuals on Alphanine 500IU Injection therapy need to be aware of their own limitations and consult with their healthcare provider regarding driving safety.
Side Effects of Alphanine 500iu Injection
Alphanine 500IU Injection causes some side effects like all medications, although not everyone will experience them.
- Allergic reactions
- Development of inhibitors
- Thrombosis (blood clots)
- Hepatitis transmission
- Liver complications
- Localized reactions
Word of Advice
Patient should be aware of the potential for allergic reactions and promptly report any signs, such as hives or difficulty breathing. Regular monitoring of Alphanine 500IU Injection levels is crucial, especially for inhibitor development, as adjustments to the treatment plan may be needed. Patients with liver or kidney conditions should exercise caution, as should those receiving live vaccines, to avoid potential interactions. In surgical or dental procedures, healthcare providers should be informed to make necessary treatment adjustments. Patients should also be mindful of alcohol intake, especially given its impact on liver function, and practice safe driving. An emergency plan for bleeding episodes and access to psychosocial support can further enhance the safety and well-being of individuals with hemophilia B.
Q 1. How often is Alphanine 500IU Injection replacement therapy required?
The frequency of Alphanine 500IU Injection replacement therapy depends on the severity of hemophilia B and the treatment plan developed by healthcare providers. Some individuals may require regular prophylactic treatment, while others only need it when experiencing bleeding episodes.
Q 2. Are there any side effects or risks associated with Alphanine 500IU Injection replacement therapy?
While Alphanine 500IU Injection replacement therapy is generally safe and well-tolerated, there can be risks, including allergic reactions, inhibitor development, and thrombosis (blood clot formation). Patients should discuss potential risks with their healthcare providers.
Q 3. What should I do in case of a bleeding emergency while on Alphanine 500IU Injection therapy?
Individuals on Alphanine 500IU Injection therapy should contact their healthcare provider or seek immediate medical attention if a bleeding emergency occurs. In some cases, they may be trained to administer Alphanine 500IU Injection at home for quick response to bleeding episodes.
Q 4. Can Alphanine 500IU Injection replacement therapy be self-administered at home?
Some individuals with hemophilia B are trained to self-administer Alphanine 500IU Injection at home. This can provide convenience and rapid access to treatment when needed, especially for prophylactic regimens.
Q 5. Are there any dietary restrictions while on Alphanine 500IU Injection therapy?
There are usually no specific dietary restrictions while on Alphanine 500IU Injection therapy. However, maintaining a balanced diet and staying hydrated can support overall health and well-being for individuals with hemophilia B.
Q 6. Is participating in sports and physical activities possible while on Alphanine 500IU Injection therapy?
With proper management and treatment, individuals with hemophilia B can participate in sports and physical activities. They should work closely with their healthcare providers to develop a safe exercise regimen and take precautions to prevent injuries.
Fact Box of Alphanine 500iu Injection
Molecule name: Factor IX
Therapeutic class: Hemostatic Agent
Pharmacological class: Coagulation Factor - Antihemorrhagic
1. Treatment of hemophilia B
2. Prophylactic treatment
3. Management of bleeding episodes
4. Surgical procedures
5. Trauma and injuries
6.Alternative treatment for hemophilia A with inhibitors
7.Other bleeding disorders
8. Pediatric hemophilia B
- Octapharma Limited, Electronic Medicines Compendium (EMC), [Revised on 04 Jan 2022] [Accessed on 2nd September 2023], https://www.medicines.org.uk/emc/product/6566/smpc#gref
- NA Orlova et al; Factor IX for Haemophilia B therapy; Acta Naturae 2012; [Accessed: 2nd September 2023], https://pubmed.ncbi.nlm.nih.gov/22872812/
- T Zögg; Activation mechanisms of coagulation factor IX; Biological Chemistry 2009; [Accessed:2nd September 2023]], https://pubmed.ncbi.nlm.nih.gov/193612
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