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Aplex Kit
Prescription Required
Salt Composition : Apremilast
Manufacturer : AJANTA PHARMA LTD
Origin of Medicine : India
13 Tablet(s) In A Strip
Introduction to Aplex Kit
Aplex Kit contains an active component called Apremilast. It is indicated for treating moderate to severe plaque psoriasis, a chronic autoimmune condition characterised by patches of abnormal skin. It can help reduce the affected skin's redness, scaling, and thickness. It is also used to treat active psoriatic arthritis, a type of arthritis that affects some people with psoriasis.
This medication should not be used in individuals with a known hypersensitivity or allergic reaction to it or its components. It is associated with risks to the developing fetus and is contraindicated during pregnancy. The dosage adjustment of Aplex Kit is required in patients with severe renal impairment because the drug is primarily excreted through the kidneys.
There is limited information about using this Aplex Kit in the elderly population. Therefore, caution should be exercised in older adults, and the dosage may need adjustment based on individual health conditions and renal function. It has not been studied in children under 18, and its safety and efficacy in this population have yet to be established.
Uses of Aplex Kit
Aplex Kit is used in the treatment of the following:
- Plaque psoriasis
- Psoriatic arthritis
Therapeutic Effects of Aplex Kit
Aplex Kit works by inhibiting an enzyme called phosphodiesterase 4 (PDE4), which regulates the production of certain inflammatory mediators. Reducing the activity of PDE4 helps to decrease the levels of these inflammatory mediators, thereby alleviating the symptoms associated with psoriasis and psoriatic arthritis.
Interaction of Aplex Kit with other drugs
Inform the doctor about your medicines, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Aplex Kit, reducing effectiveness by causing undesirable side effects.
More Information about Aplex Kit
- Store at room temperature, between 20°C to 25°C
- Keep away from moisture, heat, and light.
- It should not be frozen.
- Keep away from children and pets.
How to consume Aplex Kit
Aplex Kit is administered orally in the form of tablets. It is taken orally with or without food, as directed by a healthcare professional. The recommended starting dosage and any necessary dose adjustments are determined based on the specific condition being treated and the individual patient's response to the medication.
Safety Advices for Aplex Kit
Pregnancy
Aplex Kit is unsafe during pregnancy due to the potential risks to the developing fetus.
Breast Feeding
Aplex Kit is unsafe if you are breastfeeding as it may pass into human milk, and there is a potential risk to the nursing infant.
Lungs
Consult your healthcare provider if you have a history of lung conditions before using the Aplex Kit.
Liver
Patients with liver dysfunction should consult a healthcare provider before taking the Aplex Kit.
Alcohol
It is not safe to consume excessive alcohol when taking any Aplex Kit as it may exacerbate certain side effects of this medication, such as gastrointestinal disturbances.
Driving
Aplex Kit is not known to impair the ability to drive or operate machinery. However, consult your healthcare provider if you experience side effects such as dizziness.
Side Effects of Aplex Kit
Aplex Kit causes some side effects like all medications, although not everyone will experience them.
Serious side effects of Aplex Kit are:
- Mood and mental health
- Gastrointestinal disturbances
- Allergic reactions
Common side effects of Aplex Kit are:
- Gastrointestinal effects
- Neurological effects
- Respiratory tract infections
- General symptoms
Word of Advice
Be cautious if you have a history of depression or mood disorders before taking Aplex Kit. Report any changes in mood or behavior to your healthcare provider. Watch for gastrointestinal issues like diarrhea or nausea, and stay hydrated. Inform your doctor if you experience severe or persistent symptoms. Keep an eye on your weight while taking Aplex Kit, as it may lead to weight loss. Report any significant or unexplained weight changes to your healthcare provider.
Be vigilant for signs of infection, such as fever or persistent cough, and promptly report any concerns to your doctor. Avoid live vaccinations while on this medication, which may affect your immune response. Consult your healthcare provider before receiving any vaccines. Use it with caution if you have a history of liver or kidney problems, and follow your doctor's instructions for regular monitoring.
Seek medical attention immediately if you notice any signs of allergic reactions, such as rash or swelling. Stick to the prescribed dosage. Do not stop taking it without consulting your healthcare provider. Be aware of any potential side effects and communicate any concerns promptly.
FAQs
Q 1. What should I do if I miss a dose of Aplex Kit?
If you miss a dose of Aplex Kit, take it as soon as you remember unless it is almost time for your next dose. In that case, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for the missed one.
Q 2. Can Aplex Kit be used in patients with a history of mental health issues?
Aplex Kit should be used cautiously in patients with a history of depression, mood disorders, or suicidal thoughts. Discussing your medical history thoroughly with your healthcare provider before starting this medication is essential.
Q 3. How long does it take for Aplex Kit to work?
The response to Aplex Kit can vary among individuals. Some patients may start noticing improvements in their symptoms within a few weeks, while others may take longer. It is essential to continue taking the medication as your healthcare provider prescribes.
Q 4. How often do I need to see my healthcare provider while taking Aplex Kit?
Regular follow-up appointments with your healthcare provider are important to monitor your response to Aplex Kit and assess for potential side effects or complications. The frequency of these visits will be determined based on your treatment plan and health status.
Q 5. Can Aplex Kit be taken with food?
Aplex Kit can be taken with or without food, as directed by your healthcare provider. It is essential to follow the specific instructions in the medication guide or as your doctor advises.
Q 6. What should I do if I experience severe side effects while taking Aplex Kit?
Consult your healthcare provider immediately if you experience severe or persistent side effects, such as allergic reactions, gastrointestinal issues, or mood changes after taking Aplex Kit. They can guide whether any adjustments to the treatment plan are necessary.
Fact Box of Aplex Kit
| Molecule name: Apremilast | Therapeutic class: Immunomodulatory agent |
| Pharmacological class: Phosphodiesterase 4 (PDE4) inhibitor | Indications: 1. Plaque psoriasis 2. Psoriatic arthritis |
References
1. Amgen Ltd, Electronic medicines compendium (EMC), [Revised on 30th Jun 2021] [Accessed on 19th Oct 2023], https://www.medicines.org.uk/emc/product/3648/smpc#gref
2. US Food and Drug Administration, [Revised on Dec 2021 ] [Accessed on 19th 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/205437s011lbl.pdf
Disclaimer
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