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Aprecap 125mg/80mg Capsule
Last updated on 22 Jun 2026 | 11:06 AM (IST)
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Introduction to Aprecap 125mg/80mg Capsule
Aprecap 125mg/80mg capsule contains the active constituent Aprepitant in two different doses. It belongs to a class of medicines called NK1 Receptor antagonists. It is used with a combination of other medicines to prevent nausea and vomiting caused by chemotherapy (cancer treatment) in adults and children of twelve years and older. Do not take this medicine if you are allergic to this medicine or any of its other ingredients.
Before taking the Aprecap 125mg/80mg capsule, it is important to inform your physician about all the medications you have been taking recently, including supplements and herbal medicines. Notify your doctor if you are planning a pregnancy or think you might be pregnant because this medicine is unsafe to use in such conditions. This medication may reduce the efficacy of hormonal contraceptives. Talk with your doctor about alternative birth control options. Before taking this capsule, inform your doctor if you have liver disorders because the liver is crucial in breaking down medicine.
The doctor may, therefore, have to monitor the condition of the liver. Notify your doctor if you have had any allergic conditions or other diseases. Indigestion, tiredness, headache, hiccups, and loss of appetite are the common side effects of Aprecap 125mg/80mg medication. Talk to your doctor if you have an intolerance to some sugars, as this medication contains sucrose. Do not give this medicine to children under 12 years of age because the medicines have not been studied in this population.
Uses of Aprecap 125mg/80mg Capsule
Therapeutic Effects of Aprecap 125mg/80mg Capsule
Aprecap 125mg/80mg capsule blocks the action of a natural substance called neurokinin in the brain that causes nausea and vomiting. This medicine reduces the severity of chemotherapy-induced nausea and vomiting.
Interaction of Aprecap 125mg/80mg Capsule with other drugs
Inform your healthcare provider about all your medicines, including prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products. Certain medications, such as Pimpzide, Terfenadine, and Cisapride, may interact with Aprecap 125mg/80mg capsule and reduce effectiveness by causing undesirable side effects.
More Information about Aprecap 125mg/80mg Capsule
- Store at room temperature 20°C to 25°C.
- Keep out of sight and reach of children.
- Store in the original package in order to protect it from moisture.
How to consume Aprecap 125mg/80mg Capsule
Swallow the Aprecap 125mg/80mg capsule as a whole with water. Do not crush or chew the capsules. These capsules can be taken with or without food. Do not take more than recommended. If this medicine is prescribed, your physician will choose the dosage based on your medical condition because it differs for each person.
Safety Advice for Aprecap 125mg/80mg Capsule
Breast Feeding
It is unknown whether Aprecap 125mg/80mg capsule is excreted in human milk. So, it is not recommended to breastfeed while taking this capsule. Inform your physician before taking this medicine.
Alcohol
It is unknown whether consuming alcohol with Aprecap 125mg/80mg capsule. Consult your doctor for more information.
Liver
Inform your physician if you have any liver disorders before taking the Aprecap 125mg/80mg capsule, as this medication should be used with caution in liver disorder patients.
Lungs
Inform your doctor, if you have or had any lung condition before starting to take Aprecap 125mg/80mg capsule. Contact your physician immediately if you experience any lung-related symptoms such as difficulty to breath.
Driving
The medicine may make you dizzy. Avoid driving or handling heavy machines if you are unwell.
Pregnancy
This medication is unsafe because it may harm your unborn baby. Inform your physician if you are pregnant or planning to get pregnant before taking the Aprecap 125mg/80mg capsule. It will be given to you if clearly needed.
Side Effects of Aprecap 125mg/80mg Capsule
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious
- Allergic reactions (rash, itching, difficulty breathing, or swallowing)
Common
- Tiredness
- Increased liver enzyme
- Indigestion
- Constipation
- Loss of appetite
- Hiccups
- Headache
Word of Advice
Report to your doctor if you are intolerant to any type of sugar because Aprecap 125mg/80mg capsule contains sucrose. It is not advised for patients under the age of 12. Notify your doctor if you are pregnant or planning to get pregnant or if you are breastfeeding. It is not recommended to consume this medicine if you have any underlying liver conditions. Your doctor may monitor your liver to understand its functioning level.
FAQs about Aprecap 125mg/80mg Capsule
Q1.
Can Aprecap 125mg/80mg capsule be taken with other medications?
Aprecap 125mg/80mg capsule can be taken with other antiemetic drugs to provide more comprehensive prevention of chemotherapy-induced nausea and vomiting.
Q2.
Can Aprecap 125mg/80mg capsule be used to treat other conditions?
Aprecap 125mg/80mg capsule is primarily used to prevent nausea and vomiting caused by chemotherapy or surgery, but it may also be used to treat other conditions, such as migraine headaches.
Q3.
Why patients with liver conditions should not consume Aprecap 125mg/80mg capsule?
Because the Aprecap 125mg/80mg capsule initially gets metabolized in the liver. Hence patients with liver disorders will feel difficult to metabolize this medicine which may lead to an increased risk of side effects.
Q4.
What should I inform my doctor about before starting with Aprecap 125mg/80mg capsule?
You need to inform if you have any underlying liver conditions if you are allergic to Aprecap 125mg/80mg capsule and if you are intolerant to sucrose or any other sugar.
Q5.
Is Aprecap 125mg/80mg capsule safe for use during pregnancy?
Aprecap 125mg/80mg capsule should only be used during pregnancy if the potential benefits outweigh the potential risks to the fetus.
Fact Box of Aprecap 125mg/80mg Capsule
Molecule name: Aprepitant
| Therapeutic class: Antiemetic |
Pharmacological class: NK1 Receptor antagonists
| Indication: Prevents nausea and vomiting due to chemotherapy |
References
- KD Tripathi, Essentials of Medical Pharmacology, Antiemetic, Prokinetic and Digestant Drugs, 7th edition, 2013, 669-670.
- Goodman & Gilman’s, The Pharmacological Basics of Therapeutics, Treatment of disorders of bowel motility and water flux, 12th edition, 2011, 1345.
- Ethypharm, Electronic Medicines Compendium (EMC), [Revised on Oct 2022]; [Accessed on 19th April 2023], https://www.medicines.org.uk/emc/files/pil.14650.pdf
- Merck Sharp & Dohme Corp, US Food and Drug Administration, [Revised date April 2015], [Accessed on 19th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/021549s025lbl.pdf
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details
Written By
Sakshi Anil More
B. Pharm
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 22 Jun 2026 | 11:06 AM (IST)
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