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Apregur Kit 125/80 Capsule
Last updated on 26 Sep 2026 | 08:41 AM (IST)
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Introduction
The Apregur Kit 125/80 Capsule contains Aprepitant in two different doses. It belongs to a class of medicines called NK1 receptor antagonists and is commonly prescribed to prevent nausea and vomiting caused by chemotherapy in adults and children twelve years and older. This aligns with established Apregur Kit 125/80 Capsule uses and answers the question, What is Apregur Kit 125 80 Capsule used for? Do not take this medicine if you are allergic to Aprepitant or any of its ingredients.
Before taking the Apregur 125/80 Capsule, inform your physician about all medications you are currently using, including supplements and herbal products. Notify your doctor if you are planning a pregnancy or think you might be pregnant, as this medicine is unsafe during pregnancy. This medication may also reduce the effectiveness of hormonal contraceptives, so discuss alternative birth control methods with your doctor. If you have liver disorders, inform your physician because the liver plays a key role in breaking down this medicine, and monitoring may be required.
Notify your doctor if you have had any allergies or other medical conditions. Common Apregur Kit 125/80 Capsule side effects include indigestion, tiredness, headache, hiccups, and loss of appetite. If you have an intolerance to certain sugars, talk to your doctor, as this medication contains sucrose. Do not give this medicine to children under 12 years of age, as it has not been studied in this age group.
For patients comparing costs, the Apregur Kit 125/80 Capsule price may vary by pharmacy and region. Many individuals prefer the convenience of buy Apregur Kit 125/80 Capsule online through trusted, verified medical platforms.
Uses
The Apregur Kit 125/80 Capsule is uses for the treatment of the following:
Prevents nausea and vomiting due to chemotherapy
How Apregur Kit 125/80 Capsule Works
The Apregur Kit 125/80 Capsule blocks the action of a natural substance called neurokinin in the brain that causes nausea and vomiting. This medicine reduces the severity of chemotherapy-induced nausea and vomiting.
Interaction of Apregur Kit 125/80 Capsule with other drugs
Inform your healthcare provider about all your medicines, including prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products. Certain medications, such as Pimpzide, Terfenadine, and Cisapride, may interact with the Apregur Kit 125/80 Capsule and reduce effectiveness by causing undesirable side effects.
Storage conditions
Store at room temperature 20°C to 25°C.
Keep out of sight and reach of children.
Store in the original package in order to protect it from moisture.
How to take Apregur Kit 125/80 Capsule
Swallow the Apregur Kit 125/80 Capsule as a whole with water. Do not crush or chew the capsules. These capsules can be taken with or without food. Do not take more than recommended. If this medicine is prescribed, your physician will choose the Apregur Kit 125/80 Capsule dosage based on your medical condition because it differs for each person.
Safety Advices
Pregnancy
This medication is unsafe because it may harm your unborn baby. Inform your physician if you are pregnant or planning to get pregnant before taking the Apregur Kit 125/80 Capsule. It will be given to you if clearly needed.
Breast Feeding
It is unknown whether the Apregur Kit 125/80 Capsule is excreted in human milk. So, it is not recommended to breastfeed while taking this capsule. Inform your physician before taking this medicine.
Lungs
Inform your doctor if you have or have had any lung condition before starting to take the Apregur Kit 125/80 Capsule. Contact your physician immediately if you experience any lung-related symptoms, such as difficulty breathing.
Liver
Inform your physician if you have any liver disorders before taking the Apregur Kit 125/80 Capsule, as this medication should be used with caution in liver disorder patients.
Alcohol
It is unknown whether consuming alcohol with an Apregur Kit 125/80 Capsule is. Consult your doctor for more information.
Driving
The medicine may make you dizzy. Avoid driving or handling heavy machines if you are unwell.
Side Effects
Apregur Kit 125/80 Capsule side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them.
Serious side effects of the Apregur Kit 125/80 Capsule are:
Allergic reactions (rash, itching, difficulty breathing, or swallowing)
Common side effects of the Apregur Kit 125/80 Capsule are:
Tiredness
Increased liver enzyme
Indigestion
Constipation
Loss of appetite
Hiccups
Headache
Expert Tips
Report to your doctor if you are intolerant to any type of sugar because the Apregur Kit 125/80 Capsule contains sucrose.
It is not advised for the patient under the age of 12. Notify your doctor if you are pregnant or planning to get pregnant or if you are breastfeeding.
It is not recommended to consume this medicine if you have any underlying liver conditions. Your doctor may monitor your liver to understand its functioning level.
Frequently Asked Questions(FAQs)
Q1.
Can the Apregur Kit 125/80 Capsule be taken with other medications?
Apregur Kit 125/80 Capsule can be taken with other antiemetic drugs to provide more comprehensive prevention of chemotherapy-induced nausea and vomiting.
Q2.
Can the Apregur Kit 125/80 Capsule be used to treat other conditions?
Apregur Kit 125/80 Capsule is primarily used to prevent nausea and vomiting caused by chemotherapy or surgery, but it may also be used to treat other conditions, such as migraine headaches.
Q3.
Why patients with liver conditions should not consume an Apregur Kit 125/80 Capsule?
Because the Apregur Kit 125/80 Capsule initially gets metabolised in the liver. Hence, patients with liver disorders will find it difficult to metabolise this medicine, which may lead to an increased risk of side effects.
Q4.
What should I inform my doctor about before starting with the Apregur Kit 125/80 Capsule?
You need to inform your doctor if you have any underlying liver conditions, are allergic to the Apregur Kit 125/80 Capsule, or are intolerant to sucrose or any other sugar.
Q5.
Is the Apregur Kit 125/80 Capsule safe for use during pregnancy?
Apregur Kit 125/80 Capsule should only be used during pregnancy if the potential benefits outweigh the potential risks to the fetus.
Fact Box
Molecule name: | Aprepitant |
Pharmacological class: | NK1 Receptor antagonists |
Therapeutic class: | Antiemetic |
Indication: | Prevents nausea and vomiting due to chemotherapy |
References
1. KD Tripathi, Essentials of Medical Pharmacology, Antiemetic, Prokinetic and Digestant Drugs, 7th edition, 2013, 669-670.
2. Goodman & Gilman’s, The Pharmacological Basics of Therapeutics, Treatment of disorders of bowel motility and water flux, 12th edition, 2011, 1345.
3. Ethypharm, Electronic Medicines Compendium (EMC), [Revised on Oct 2022]; [Accessed on 19th April 2023], https://www.medicines.org.uk/emc/files/pil.14650.pdf
4. Merck Sharp & Dohme Corp, US Food and Drug Administration, [Revised date April 2015], [Accessed on 19th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/021549s025lbl.pdf
Disclaimer
MrMed’s primary intention is to ensure that its consumers get information that is reviewed by experts, accurate and trustworthy. The information and contents of this website are for informational purposes only. They are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of your doctor and discuss all your queries related to any disease or medicine. Do not disregard professional medical advice or delay in seeking it because of something you have read on MrMed. Our mission is to support, not replace, the doctor-patient relationship.
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Author Details
Written By
P. Thirumal Reddy
B. Pharm
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 26 Sep 2026 | 08:41 AM (IST)
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