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Asviia 3750IU Injection 5ml
Prescription Required
Salt Composition : Pegaspargase
Manufacturer : ZYDUS CADILA
Origin of Medicine : India
1 Vial(s) Of 5ml
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Introduction to Asviia 3750iu Injection 5ml
Asviia 3750IU/5ML Injection is a chemotherapy drug containing the active constituent Pegaspargase. It is used to treat a type of blood cancer called Acute Lymphoblastic Leukemia (ALL). This is a white blood cell cancer in which the immature white cells start growing out of control, thus preventing the production of functional blood cells. Combined with other chemotherapy drugs, this medication can help increase the chances of remission and long-term survival for people with ALL. It is particularly effective in treating children with ALL, who have a higher remission rate and overall survival when included in their treatment plan.Â
Asviia 3750IU/5ML Injection is typically used with other chemotherapy agents to treat ALL, particularly in patients who have not responded to other treatments or who have relapsed after initial treatment. Glucose intolerance can occur with the administration of Asviia 3750IU/5ML Injection. Contact your doctor if you experience severe headaches, abdominal pain, excessive thirst, or serious allergic reactions while taking this medicine. Patients with previous kidney and pancreatic disease should talk to their healthcare provider before taking this medication.
Uses of Asviia 3750iu Injection 5ml
Asviia 3750IU/5ML Injection is indicated to treat the following conditions:Â
- Acute Lymphoblastic Leukemia
- Non-Hodgkin's Lymphoma
Therapeutic Effects of Asviia 3750iu Injection 5ml
Asviia 3750IU/5ML Injection is an enzyme that breaks down the amino acid asparagine in the body. Cancer cells require asparagine to grow and divide and cannot produce their asparagine. By breaking down asparagine in the body, this medication can effectively "starve" cancer cells of this essential nutrient, slowing their growth and promoting cancer cell death. However, normal cells in the body can produce their asparagine and are not as affected by the enzyme as cancer cells. Therefore, this medicine selectively targets cancer cells while sparing healthy cells in the body to some extent.
Interaction of Asviia 3750iu Injection 5ml with other drugs
Inform your healthcare provider about all the medicines you take, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Asviia 3750IU/5ML Injection and reduce effectiveness by causing undesirable side effects.
More Information about Asviia 3750iu Injection 5ml
- Store in a refrigerator at 2-8°C.
- Do not freeze.
- Protected from light.
- Keep it in its original packaging until it is ready to be used.
- Keep out of the reach of children and pets.
- Should be disposed of properly.
How to consume Asviia 3750iu Injection 5ml
Asviia 3750IU/5ML Injection is typically administered by a healthcare provider as an intravenous (IV) injection in a clinical setting. The dosage and frequency of infusions will vary depending on the patient's medical condition, age, weight, and other factors. You should not take a double dose to make up the second dose.
Safety Advices for Asviia 3750iu Injection 5ml
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Pregnancy
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There are no established adverse effects of Asviia 3750IU/5ML Injection in pregnant women. Consult your doctor if you are pregnant or planning to get pregnant before taking this medicine.
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Breast Feeding
 ÂIt is unclear whether Asviia 3750IU/5ML Injection is excreted in human milk. So you should consult a doctor before taking this medication if you are a breastfeeding mother.
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Lungs
  There is no evidence to suggest that Asviia 3750IU/5ML Injection harms the lungs. However, as with any medication, there is a risk of side effects that could affect the respiratory system. So patients should consult their doctor if they have any pre-existing lung disease before taking this medication.
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Liver
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Asviia 3750IU/5ML Injection is primarily metabolized in the liver, so inform your healthcare provider if you have any liver problems or diseases. This medication may also increase liver enzymes, which can be a sign of liver damage or inflammation. Patients taking this medication require regular blood tests to monitor liver function.
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Alcohol
 ÂIt is recommended to avoid consuming alcohol while taking Asviia 3750IU/5ML Injection, as alcohol can increase the risk of certain side effects associated with the medication, such as stomach ulcers or gastrointestinal bleeding.
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Driving
  Patients receiving Asviia 3750IU/5ML Injection should be advised to avoid driving or operating machinery if they experience side effects such as fatigue, dizziness, or blurred vision, impairing a patient's ability to drive or operate machinery safely.
Side Effects of Asviia 3750iu Injection 5ml
Like all medications, Asviia 3750IU/5ML Injection can cause side effects, although not everyone who takes it will experience them.Â
Serious:
- Anaphylaxis (severe allergic reaction)
- Thrombosis (blood clots)
- Hemorrhage (bleeding)
- Tumor Lysis Syndrome (a potentially life-threatening condition due to the breakdown of cancer cells)
- Acute pancreatitis (inflammation of the pancreas)
- Hepatotoxicity (liver damage or failure)
- Neurotoxicity (damage to the nervous system)
- Hypersensitivity reactions (allergic reactions, including anaphylaxis)
- Renal failure (kidney damage or failure)Â
Common:Â
- Nausea
- Vomiting
- Diarrhea
- Fatigue
- Loss of appetite
- Headache
- Fever or chills
- Muscle or joint pain
- Rash or itching
- Swelling or redness at the injection site
Word of Advice
If you are receiving treatment with Asviia 3750IU/5ML Injection, report any side effects or concerns promptly. If you are pregnant or planning to become pregnant or breastfeeding, it is important to discuss the risks and benefits with your healthcare provider. If patients see any sign of jaundice (yellow skin and eyes, abdominal pain, vomiting) after taking this medication, they should contact a doctor immediately because it can cause pancreas inflammation.
Patients require close monitoring for any signs of abnormal bleeding or clotting. Making lifestyle changes, such as quitting smoking, maintaining a healthy weight, and eating a healthy diet, can also help support your overall health and reduce the risk of cancer-related complications. Additionally, seeking support from family members, friends, or support groups can provide patients with emotional support and help them cope with the challenges of cancer treatment.
FAQs
Q 1. Can I take Asviia 3750IU/5ML Injection if I have diabetes?
Patients with diabetes may still be able to use Asviia 3750IU/5ML Injection, but caution is needed as the medication can cause glucose intolerance and hyperglycemia. Patients with a history of diabetes should be closely monitored for signs of high blood sugar, such as increased thirst, urination, and fatigue, during treatment.
Q 2. Can I use Asviia 3750IU/5ML Injection if I have kidney disease?
Patients with kidney disease may still be able to use Asviia 3750IU/5ML Injection, but caution is needed as the medication can cause kidney toxicity. Dosing and monitoring may need to be adjusted based on the severity of kidney disease.
Q 3. How will Asviia 3750IU/5ML Injection affect my blood?
Asviia 3750IU/5ML Injection can cause blood clotting disorders, leading to serious or life-threatening bleeding or clotting. Patients should be closely monitored for signs of abnormal bleeding or clotting.
Q 4. Can Asviia 3750IU/5ML Injection be given to patients with a history of pancreatitis?
It depends on the severity and cause of pancreatitis. Patients with a history of pancreatitis may be at increased risk of experiencing pancreatitis while using Asviia 3750IU/5ML Injection. However, if the benefits of using this medication outweigh the risks, it may sometimes be used with careful monitoring.
Q 5. How long does the effect of Asviia 3750IU/5ML Injection last?
The effect of Asviia 3750IU/5ML Injection may last several weeks, depending on the patient's medical condition and response to treatment.
Fact Box of Asviia 3750iu Injection 5ml
Molecule name: Pegaspargase | Therapeutic class: Anticancer |
Pharmacological class:Â Asparagine-specific enzyme inhibitors
| Indications:Â 1. Acute Lymphoblastic Leukemia 2. Non-Hodgkin's Lymphoma |
References
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 868
- Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1720
- Les Laboratories Servier, Electronic medicines compendium (EMC), [ Revised on Nov 2021] [ Accessed on 25th April 2023], https://www.medicines.org.uk/emc/files/pil.10824.pdf
- Sigma-Tau Pharmaceuticals, US Food, and Drug Administration, [ Revised on March 2011] [ Accessed on 25th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/103411s5126lbl.pdf
Disclaimer
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