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Azacbuzz 100mg Injection
Prescription Required
Salt Composition : Azacitidine
Manufacturer : JASGUR LIFE SCIENCES LLP
Origin of Medicine : India
1 Vial(s)
Introduction to Azacbuzz 100mg Injection
Azacbuzz 100mg Injection consists of the active ingredient Azacitidine. It is used for treating adults with blood conditions, namely Myelodysplastic syndrome (MDS), chronic myelomonocytic leukemia and Acute myeloid leukemia (AML) if they are considered ineligible for stem cell transplant.
In Myelodysplastic Syndrome, the bone marrow does not produce healthy blood cells due to its lack of function. Acute Myeloid Leukemia is a type of bone marrow cancer caused by the release of incompletely formed blood cells into the bloodstream. Chronic myelomonocytic leukemia is a rare form of blood cancer caused by an increased number of monocytes of the white blood cells.
Uses of Azacbuzz 100mg Injection
This medicine is indicated to treat the following conditions:
- Acute Myeloid Leukemia with 20-30% blasts in patients who are not eligible for Haemopoietic stem cell transplant
- High-risk Myelodysplastic syndrome (MDS)
- Chronic myelomonocytic leukemia.
Therapeutic Effects of Azacbuzz 100mg Injection
Azacbuzz 100mg Injection binds to RNA and DNA, interrupts their activity in actively multiplying cells and exhibits a toxic effect on cancer cells.
Interaction of Azacbuzz 100mg Injection with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Azacbuzz 100mg Injection and cause undesirable side effects.
More Information about Azacbuzz 100mg Injection
- Store at 25°C.
- Keep out of reach of children.
How to consume Azacbuzz 100mg Injection
Take Azacbuzz 100mg Injection only under the supervision of your physician. Your physician will decide the dose based on your height, weight and general condition. Azacbuzz 100mg Injection shall be given under the skin of your thigh, stomach or upper arm.
Safety Advices for Azacbuzz 100mg Injection
Pregnancy
This medicine is not intended for use during pregnancy. Talk to your physician if you are pregnant or think you could be pregnant.
Breast Feeding
Consult your physician for advice on taking this medicine if you are a breastfeeding mother.
Lungs
Inform your physician before you take this medicine if you are diagnosed with a tumor in the lungs.
Liver
Inform your physician before you take this medicine if you are diagnosed with a tumor in the liver cells.
Alcohol
It is not known whether it is safe to consume alcohol with Azacite 100mg Injection. Please consult your doctor.
Driving
Exercise caution while driving and using machines during this treatment.
Side Effects of Azacbuzz 100mg Injection
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
Serious:
- Drowsiness
- Shivering
- Jaundice
- Stomach bloating
- Unusual bleeding or bruising
- Reduced urination
- Increased thirst
- Dizziness
- Confusion
- Chest pain
- Breathlessness
- Allergies
Common:
- Disturbances in the blood count (RBC, WBC, Platelets)
- Nausea, vomiting, diarrhea
- Constipation
- Tiredness
- Skin reaction like redness and pain at the site of injection
- Decreased appetite
- Dizziness
- Pain in extremities
- Joint pain
- Stomach pain
- Headache
- Sore nose and throat
- Rashes and bruising
Word of Advice
Inform the doctor if the patient has any allergy reactions, respiratory problems,kidney, liver, heart problems and medication taken for different medical conditions before taking this injection as they worsen the condition. Avoid using this injection if the patient is planning for pregnancy or during pregnancy and in breast feeding mothers as this medicine causes harmful effects in the developing baby. Take this injection only under the supervision of the physician. Doctors will decide the dose based on the patient's height, weight and general condition. It is administered under the skin of your thigh, stomach or upper arm.
FAQs
Q 1. How to use Azacbuzz 100mg Injection?
Take Azacbuzz 100mg Injection only under the supervision of the physician. Doctor’s will decide the dose based on patients height, weight and general condition. Azacbuzz 100mg Injection is administered under the skin of your thigh, stomach or upper arm.
Q 2. Does Azacbuzz 100mg Injection cause hair loss?
No, Azacbuzz 100mg Injection does not cause hair loss even after using for a prolonged period of time.
Q 3. How does Azacbuzz 100mg Injection work?
Azacbuzz 100mg Injection binds to RNA and DNA, interrupts their activity in actively multiplying cells and exhibits a toxic effect on cancer cells.
Q 4. Is Azacbuzz 100mg Injection chemotherapy?
Yes. Azacbuzz 100mg Injection is chemotherapy and it is used in the treatment of cancers. It interferes with the cell's DNA synthesis and decreases the growth and multiplication (cytotoxic effect).
Q 5. What are the side effects of Azacbuzz 100mg Injection?
The common side effects of Azacbuzz 100mg Injection are Nausea, vomiting, diarrhea, constipation, tiredness, decreased appetite, rashes, redness of skin, dizziness, joint pain, headache, sore throat and nose.
Q 6. Is it safe to drive after taking Azacbuzz 100mg Injection?
It is unsafe to drive after taking this injection as it causes dizziness and patients lack concentration and alertness. So, avoid driving and handling heavy machineries after taking this medication.
Fact Box of Azacbuzz 100mg Injection
Molecule Name: Azacitidine
| Therapeutic class: Antineoplastic agent (Anti-cancer) |
| Pharmacological Class: DNA Methyltransferase Inhibitor (Hypomethylating agent) | Indications: 1. Myelodysplastic Syndromes (MDS) 2. Acute Myeloid Leukemia (AML) 3. Chronic Myelomonocytic Leukemia (CMML) |
References
- K. Gaston and P.-S. Jayaraman, Transcriptional repression in eukaryotes: Repressors and repression mechanisms, Cellular and Molecular Life Sciences, [May 2003], 60(4):721-741, [Accessed on 5th Apr 2021] https://www.researchgate.net/publication/7094896_Transcriptional_repression_in_eukaryotes_Repressors_and_repression_mechanisms
- Roman M. Shapiro & Alejandro Lazo-Langner, Systematic review of azacitidine regimens in myelodysplastic syndrome and acute myeloid leukemia, BMC Hematology, 2018 [Accessed on 3rd Apr 2021] https://bmchematol.biomedcentral.com/articles/10.1186/s12878-017-0094-8
- Bristol-Myers Squibb, Electronic Medicines Compendium (EMC), [Revised on Oct 2021] [Accessed on 2nd Dec 2021], https://www.medicines.org.uk/emc/files/pil.6468.pdf
- Leukaemia Care, [Revised on Jul 2020] [Accessed on 2nd Dec 2021], https://media.leukaemiacare.org.uk/wp-content/uploads/Chronic-Myelomonocytic-Leukaemia-CMML-Web-Version.pdf
Disclaimer
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