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Azolyst 50mg Tablet
Last updated on 16 Apr 2026 | 06:56 AM (IST)
₹84
MRP: ₹105.3
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Introduction
Azolyst 50mg Tablet contains Azathioprine, a medicine known for its immune-suppressing properties. It is commonly prescribed for managing autoimmune diseases and preventing organ rejection after transplantation. This tablet helps reduce joint inflammation and pain in conditions like rheumatoid arthritis. Inflammatory bowel diseases such as Crohn’s disease and ulcerative colitis are other conditions where this medication plays a role by controlling immune-driven gut inflammation. Additionally, Azolyst 50mg Tablet is sometimes used in patients with lupus when other treatments fail to control the disease.
Since Azolyst 50mg Tablet works by weakening the immune system, it makes the body more vulnerable to infections. It may also lead to blood-related problems and hypersensitivity reactions, so regular medical supervision and monitoring are essential while using this medicine. Azolyst 50 mg tablet price depends on the seller and the Place. Azolyst tablet substitutes in India include other brands containing fluconazole, such as Forcan, Zocon, and Flucos.
Uses
Azolyst 50mg uses include:
Crohn’s disease
Ulcerative colitis
Lupus
Autoimmune hepatitis
Prevention of organ rejection after transplant
How Azolyst 50mg Tablet Works
Once consumed, Azolyst 50mg Tablet gets converted in the body to 6-mercaptopurine, an active form that blocks the production of DNA and RNA in rapidly dividing cells, including immune cells. This process slows down the immune system's overactive response, easing inflammation and preventing the immune system from attacking healthy tissues or rejecting transplanted organs.
Interaction of Azolyst 50mg Tablet with other drugs
Before starting Azolyst 50mg Tablet, inform your doctor about all prescription and non-prescription medicines, herbal supplements, and vitamins you are taking. Some drugs, like allopurinol or warfarin, may interact with Azathioprine and increase the risk of side effects. Your doctor may adjust your dose or suggest alternative treatments to avoid potential drug interactions.
Storage Conditions
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Store at room temperature (20°C to 25°C)
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Keep away from direct sunlight, heat, and moisture
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Do not freeze
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Keep out of reach of children and pets
How to take Azolyst 50mg Tablet
Take Azolyst 50mg Tablet by mouth with food or as directed by your healthcare provider. Swallow the tablet whole with a glass of water. Follow the prescribed dosing schedule carefully to get the maximum benefit and reduce the risk of side effects.
Safety Advice for Azolyst 50mg Tablet
Breast Feeding
This medicine can pass into breast milk and may harm the infant.
Alcohol
Avoid alcohol while taking Azolyst 50mg Tablet, as it can increase the risk of liver damage.
Liver
Use with caution. Regular liver function tests may be necessary during treatment.
Lungs
Inform your doctor if you develop cough, breathing difficulty, or chest discomfort.
Driving
If you experience dizziness or drowsiness, avoid driving or operating machinery.
Pregnancy
Not recommended during pregnancy as it may affect the developing baby. Always consult your doctor before use.
Side Effects
Like all medicines, azolyst tablet side effects can occur, though not everyone will experience them.
Serious side effects include:
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Severe allergic reactions (rash, swelling, fever)
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Liver problems (yellowing of skin or eyes)
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Inflammation of the pancreas
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Bone marrow suppression (low blood counts)
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Severe infections
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Lung inflammation
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Increased risk of certain cancers
Common side effects include:
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Nausea and vomiting
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Diarrhoea
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Loss of appetite
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Skin rash
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Headache
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Hair thinning
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Increased susceptibility to infections
Expert Tips
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Inform your doctor about any existing infections, liver or kidney issues before starting Azolyst 50mg Tablet.
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Practice good hygiene and avoid close contact with people who have infections.
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Attend all scheduled blood tests to monitor your blood cell counts and liver function.
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Use sunscreen when outdoors as this medication can make your skin more sensitive to sunlight.
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Avoid live vaccines while on treatment.
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Do not stop taking the medicine without consulting your healthcare provider.
FAQs about Azolyst 50mg Tablet
Q1.
What is the time frame for Azolyst 50mg Tablet to show results?
The effects may take a few weeks to several months to become noticeable, depending on your medical condition. Your doctor will track your progress with regular check-ups.
Q2.
Is it safe to discontinue Azolyst 50mg Tablet on my own?
No, stopping the medication suddenly can cause your symptoms to flare up or increase the risk of organ rejection. Always follow your doctor’s instructions.
Q3.
Does Azolyst 50mg Tablet cause pancreatitis?
In rare cases, it may trigger pancreatitis. Watch for severe stomach pain, nausea, or vomiting and seek immediate medical help if these occur.
Q4.
What should I do if I forget a dose of Azolyst 50mg Tablet?
Take the missed dose as soon as you remember. If it's close to the next scheduled dose, skip the missed one and continue your regular dosing routine. Do not double up.
Q5.
Is Azolyst 50mg Tablet used for viral infections like COVID-19?
No, this medicine is not effective against viral infections, including COVID-19. It is strictly used for autoimmune conditions and transplant-related therapy.
Q6.
Can I receive live vaccines while using Azolyst 50mg Tablet?
Live vaccines are not recommended during this treatment as your immune response may be weakened. Always inform your doctor before getting vaccinated.
Fact Box
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Molecule name: |
Azathioprine |
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Therapeutic class: |
Immunomodulator |
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Pharmacological class: |
Immunosuppressive agents |
|
Indications: |
1. Autoimmune diseases 2.Inflammatory bowel diseases (IBD) 3. Organ transplantation 4.Autoimmune hepatitis |
References
- Mylan, Electronic Medicines Compendium (EMC), [Revised on 05 Aug 2022] [Accessed on 7th August 2023], https://www.medicines.org.uk/emc/product/2540/smpc#gref
- Sebela Pharmaceuticals Inc., US Food & Drug Administration, [Revised on Dec 2018] [Accessed on 7th August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/016324s039lbl.pdf
Disclaimer
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Author Details
Written By
P. Thirumal Reddy
B. Pharm
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 16 Apr 2026 | 06:56 AM (IST)
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