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Bdaxit 5mg Tablet
Salt Composition : Axitinib
Manufacturer : BDR PHARMACEUTICALS INTERNATIONALS PVT LTD
Origin of Medicine : India
14 Tablet(s) In A Strip
Introduction to Bdaxit 5mg Tablet
Bdaxit 5mg tablet is an anticancer drug belonging to the class of tyrosine kinase inhibitors, containing the active ingredient Axitinib. It is used to treat advanced kidney cancer which is also known as renal cell carcinoma that originates in the cells of the kidney.
It is not recommended to undergo surgical procedures while on treatment with this drug due to the high risk of bleeding. Tell your physician before you undergo surgery or dental procedures. Get immediate medical attention if you experience itching, vision changes, confusion, or dizziness. This medicine may cause harm to an unborn baby. Tell your healthcare provider before beginning this treatment if you are pregnant or planning to have a baby. It is advised for both men and women to follow proper contraceptive methods during and one week after the last dose of this drug. Avoid breastfeeding your baby while you are on the treatment as this drug can impact the growth and development of the baby by passing into the breast milk. If you get mouth sores, weight loss, and have itchy skin, consult with your doctor.
This drug is not recommended for adolescents and children under the age of 18. Contact your doctor immediately if you experience shortness of breath, chest pain, or worsening cough. During the treatment, your doctor may periodically monitor your white blood cell counts, platelets, blood sugar, electrolytes, and kidney parameters to prevent serious complications. Some GI symptoms may also develop during the treatment such as diarrhea, nausea, vomiting, and constipation. It is necessary to report to your doctor right away.
Uses of Bdaxit 5mg Tablet
- Advanced kidney cancer
Therapeutic Effects of Bdaxit 5mg Tablet
It belongs to the category of tyrosine kinase inhibitors, which interferes with the growth of blood vessels inside the cancer cells. It also acts against a protein called receptor tyrosine kinases to interrupt cell signalling, ultimately stopping the growth and spread of cancer cells.
Interaction of Bdaxit 5mg Tablet with other drugs
Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Bdaxit 5mg tablet and reduce effectiveness by causing undesirable side effects.
More Information about Bdaxit 5mg Tablet
- Store Bdaxit 5mg tablet in the original package at room temperature (20°C to 25°C).
- Keep it out of reach from children.
How to consume Bdaxit 5mg Tablet
Your doctor will decide the dose and duration of Bdaxit 5mg tablet based on the disease condition. Always take this medicine as prescribed by your doctor. The recommended starting oral dose is 5 mg twice daily. Take the tablet at the same time every day, with or without food. Do not chew, crush, or break the tablet. Swallow the whole tablet with water. If you forgot to take the tablet, simply take your next dose at the scheduled time. Do not take a double dose to make up for a forgotten dose.
Safety Advices for Bdaxit 5mg Tablet
Bdaxit 5mg tablet is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
It is unsafe to breastfeed during the treatment with Bdaxit 5mg tablet because it may cause harm to the baby. Please consult your doctor before breastfeeding.
It is not known whether Bdaxit 5mg tablet can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Inform your doctor if you have any liver problems before taking Bdaxit 5mg tablet. Regular monitoring of liver function tests is recommended.
Consuming alcohol may affect the effectiveness of Bdaxit 5mg tablet. Stop consuming alcohol if you are taking this medicine.
It is unsafe to drive vehicles or operate heavy machinery after taking Bdaxit 5mg tablets, it may cause dizziness and impair your concentration.
Side Effects of Bdaxit 5mg Tablet
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
- Extreme tiredness and swelling
- Pressure or pain in the chest, arms, back, neck or jaw
- Numbness and weakness on one side of the body
- Difficulty speaking or communicating verbally
- Vision changes or dizziness
- Serious bleeding problems like black tarry stools, bloody cough or bloody sputum
- Severe stomach pain
- High blood pressure
- Kidney problems
- Hyper-active thyroid gland
- Sore throat
- Loss of appetite
- Joint pain
- Lack of energy
- Weight loss
- Mouth sores
- Skin itching, redness of skin and hair loss
Word of Advice
Bdaxit 5mg tablet can make you feel dizzy and weak. Avoid driving or operating heavy machines if you experience dizziness, confusion, or tiredness while on treatment with this drug. Grapefruit or grapefruit juice may also increase drug plasma concentrations and should be avoided. Some formulations of axitinib may contain lactose as an inactive ingredient in which the body is unable to digest lactose, a sugar found in milk and dairy products. It can cause symptoms such as bloating, and abdominal pain. If you have lactose intolerance, inform your doctor before starting this therapy. It is advised to avoid high-fiber foods and drink lots of fluids if you have severe diarrhea.
Q 1. What are the most common side effects of Bdaxit 5mg tablet?
The common side effects that are likely to occur while you are on the treatment with Bdaxit 5mg tablet are high blood pressure, diarrhea, nausea, vomiting, constipation, indigestion, soreness in the mouth, tongue, or throat, shortness of breath, cough, tiredness, weakness, dehydration, loss of appetite, joint pain, weight loss, headache, muscle pain, nose bleeding, tinnitus, itching, hair loss, dizziness, and inflammation of the gallbladder.
Q 2. Is it safe to use Bdaxit 5mg tablet during pregnancy?
Bdaxit 5mg tablet may cause harm to an unborn baby. Tell your healthcare provider before beginning this treatment if you are pregnant or planning to have a baby.
Q 3. Is it safe to undergo surgery during the treatment with Bdaxit 5mg tablet?
Bdaxit 5mg tablet is associated with an increased risk of bleeding complications and poor wound healing. Hence it is suggested to avoid planning for surgery and tell your physician before you undergo surgery or dental procedures. Your healthcare provider will suggest stopping the medication a day prior to the surgical procedure.
Q 4. What should you not take with Bdaxit 5mg tablet?
It is not recommended to take grapefruit and grapefruit juice while on treatment with Bdaxit 5mg tablet. Tell your healthcare provider if you are taking any prescription medicines, over-the-counter drugs, vitamins, or herbal supplements.
Q 5. What are all the dosage forms and strengths available for Bdaxit 5mg tablet?
This drug is available in the form of film-coated tablets in doses 1mg, 3mg, 5mg, and 7mg. The usual recommended dose is 5mg twice a day.
Fact Box of Bdaxit 5mg Tablet
Molecule name: Axitinib
Therapeutic class: Anticancer
Pharmacological class: tyrosine kinase inhibitors
Indications: Advanced kidney cancer
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- Pfizer Labs, Electronic Medicines Compendium(EMC), [Revised on Mar 2021] [Accessed on 23rd March 2023], https://www.medicines.org.uk/emc/files/pil.4325.pdf
- Pfizer, Fact sheet, [Revised on Sep 2012] [Accessed on 23rd March 2023], https://cdn.pfizer.com/pfizercom/news/esmo/renal_cell_carcinoma_fact_sheet.pdf
- Annex I summary of Product Characteristics - European Medicines Agency. Available at:https://www.ema.europa.eu/en/documents/product-information/inlyta-epar-product-information_en.pdf (Accessed on March 25, 2023).
- Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.
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