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Bevacirel 400mg Injection
Last updated on 10 Aug 2026 | 05:15 AM (IST)
₹11378
MRP: ₹75718
(You Save ₹64340)
1 VIAL(s) OF 16ML
Bevacirel 400 mg Injection is a prescription anticancer medicine used to treat various cancers such as colorectal cancer, lung cancer, ovarian cancer, and certain brain tumors, as advised by an oncologist. It contains bevacizumab, a monoclonal antibody that works by inhibiting vascular endothelial growth factor (VEGF), thereby reducing the formation of blood vessels that supply tumors. Bevacirel is administered under strict medical supervision as part of a structured oncology treatment plan.
Sourced from:Manufacturer Authorized Distributor
Bevacirel 400mg Injection
Salt Composition
BEVACIZUMABMarketer
RELIANCE LIFE SCIENCES PVT LTD
Prepaid Only. Non-Returnable.
85% OFF
₹11378
MRP: ₹75,718.00
Inclusive of all taxes
85% Off
Salt Composition
BEVACIZUMABMarketer
RELIANCE LIFE SCIENCES PVT LTD
Prepaid Only. Non-Returnable.
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Introduction
Bevacirel 400mg Injection is an anticancer medication containing Bevacizumab as the active ingredient. It works by blocking the growth of blood vessels that supply oxygen and nutrients to tumours, thereby slowing or stopping cancer progression. This injection is used in combination with other chemotherapy drugs to treat several types of cancers, including lung cancer, brain tumors, colorectal cancer, breast cancer, cervical cancer, kidney cancer, and ovarian cancers.
The Bevacirel Injection dosage for lung cancer and other cancers varies depending on the patient’s weight, overall health, and treatment response. It is administered as an intravenous infusion under the supervision of an oncologist. Patients undergoing treatment are advised to use effective birth control during therapy and for at least six months after the final dose, as the drug can affect fertility. Breastfeeding should also be avoided during treatment.
The Bevacirel 400mg Injection for eye treatment may be prescribed in rare cases under specialist supervision to manage certain vision-threatening conditions caused by abnormal blood vessel growth. This medicine requires Bevacirel 400mg cold chain storage at recommended temperatures to maintain its stability and effectiveness.
Manufactured by Reliance Life Sciences, the Reliance Bevacirel 400mg price is often more affordable compared to similar brands. Patients can buy Bevacirel 400mg Injection online from verified pharmacies ensuring safe handling and delivery. The Bevacirel 400mg Injection price may differ based on location and hospital procurement.
Doctors may also suggest a Bevacirel 400mg substitute such as Cizumab or other biosimilars. A Bevacirel 400mg vs Cizumab 400mg comparison often highlights similar efficacy since both contain the same active ingredient. In certain cases, it is used as Bevacirel 400mg for brain tumor management when combined with radiation or chemotherapy.
Patients facing financial challenges may explore the Bevacirel 400mg Patient Assistance Program, which provides cost support through authorized distributors or oncology foundations.
Uses
Bevacirel 400mg usesin the following conditions:
Glioblastoma multiforme (brain cancer)
Persistent, recurrent, or metastatic breast cancer
Metastatic cervical cancer
Advanced kidney cancer
Metastatic colorectal cancer
Advanced non-small-cell lung cancer
Liver Cancer- Hepatocellular carcinoma
Cancers of the ovary, cervical, fallopian tube, or primary peritoneal cancer
How Bevacirel 400mg Injection works
Bevacirel 400mg Injection is a recombinant humanized monoclonal antibody that works as a targeted therapy in the treatment of various advanced cancers. It produces its action by selectively binding to the protein called vascular endothelial growth factor A (VEGF-A), present in the lining of blood and lymph vessels in the body. It interrupts the interaction of VEGF-A with its receptors. This further inhibits the formation of blood vessels that supply oxygen and nutrients to the tumor. As a result, it slows down the rate of progression of cancer.
Interaction of Bevacirel 400mg Injection with other drugs
Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional and vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with Bevacirel 400mg Injection and cause undesirable side effects.
Storage conditions
Store Bevacirel 400mg Injection at 2˚C to 8˚C. Do not freeze or shake.
Protect from light. Keep out of reach of children.
How to use Bevacirel 400mg Injection
Your physician or nurse will administer Bevacirel 400mg Injection as an intravenous infusion. The infusion should be given immediately after the dilution.
Safety Advice for Bevacirel 400mg Injection
Breast Feeding
It is recommended to avoid breastfeeding for a minimum of 6 months after your treatment with Bevacirel 400mg Injection as this medicine may interfere with the growth of your child.
Alcohol
Consult your doctor to know if it is safe to consume while you are on treatment with Bevacirel 400mg Injection as only limited studies are available.
Liver
Inform your physician before starting Bevacirel 400mg Injection if you have liver diseases to avoid any serious side effects.
Lungs
Infor your doctor if you have any lung conditions before starting treatment with Bevacirel 400mg injection
Driving
Avoid driving or using machinery while you are on your treatment with Bevacirel 400mg Injection as it is related to cause dizziness or sleepiness.
Pregnancy
Inform your physician before starting your treatment with Bevacirel 400mg Injection in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Bevacirel 400mg side effects are
Serious:
Headache
Vision changes
Confusion
Severe allergic reactions
High Blood pressure
Delayed wound healing following surgery
Protein in urine
Severe infections
Blood clots in arteries and blood vessels of lungs
Gut perforation
Nosebleeds and bleeding risk
Heart problems with an increase in heart rate
Mouth sores, dryness
Shortness of breath
Common:
Numbness in hands or feet
Weakness and lack of energy
Diarrhoea, nausea, vomiting, abdominal pain
Constipation
Loss of appetite
Weight loss
Changes in taste and speech
Decrease in counts of white blood cells
Fever
Dry skin
Back pain
Expert tips
It is vital to inform your physician before taking Bevacirel 400mg Injection if you have the following conditions:
Have conditions involving inflammation in the stomach (ulcer, colitis).
Experience allergic reactions to Bevacirel 400mg Injection or its ingredients.
Have recently undergone surgery as it is associated with the risk of bleeding.
Have diabetes, hypertension, or heart problems.
FAQs about Bevacirel 400mg Injection
Q1.
Is Bevacirel 400mg Injection used as standalone treatment in cancers?
Bevacirel 400mg Injection is a recombinant monoclonal antibody that belongs to the immunotherapy class of cancer treatment. It can either be used as monotherapy or in combination with chemotherapy or immunotherapy medications to improve the overall survival rate.
Q2.
Is it safe for women to use Bevacirel 400mg Injection?
While for women with reproductive potential subjected to Bevacirel 400mg Injection, it is advised to discuss with your doctor regarding the effective birth control methods during the treatment. Also to be continued for a minimum of 6 months after the treatment course completion as this medicine may impair fertility.
Q3.
Is it safe to undergo a surgery during the treatment with Bevacirel 400mg Injection?
Bevacirel 400mg Injection is associated with increased risk of bleeding complications and poor wound healing. Hence it is suggested to avoid planning for surgery and maintain an interval of 28days before or after surgery.
Q4.
Do the side effects of Bevacirel 400mg Injection last for a chronic period?
All the side effects that are relatively caused by Bevacirel 400mg Injection occur until the drug concentration stays in the body. It is found that this medicine will be contained in our body for almost 4 months after the final dose.
Q5.
Can I take Bevacirel 400mg Injection if I am pregnant?
Inform your physician before starting your treatment with Bevacirel 400mg Injection in case, if you are pregnant or planning for pregnancy as this medicine may cause harm to the unborn baby and interrupt the formation of blood vessels.
Fact Box
Molecule name | Bevacizumab |
Therapeutic class | Anticancer |
Pharmacological class | VEGF Inhibitor |
Indications | 1. Glioblastoma multiforme (brain cancer) 2. Persistent, recurrent, or metastatic breast cancer 3. Metastatic cervical cancer 4. Advanced kidney cancer 5. Metastatic colorectal cancer 6. Advanced non-small-cell lung cancer 7. Liver Cancer- Hepatocellular carcinoma 8. Cancers of the ovary, cervical, fallopian tube, or primary peritoneal cancer |
References
1. Roche Products Limited, Electronic Medicines Compendium (EMC), [Revised on Jan 2022] [Accessed on 21/11/2022], https://www.medicines.org.uk/emc/files/pil.3885.pdf
2. G.G. Dark, A.R. Abdul Razak, Oncology, Davidson's Principles & Practice of Medicine, 22nd Edition, 2014, 259-282.
3. KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.
4. Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976.
5. Roche Group, U.S FDA, [Revised on Jan 2021][ Accessed on 21/11/2022], https://www.gene.com/download/pdf/avastin_prescribing.pdf
6. Roche Group,Bevacizumab Injection, Indication,[Revised on 2020] [Accessed on 21/11/2022]https://www.avastin.com/patient/mcrc.html
Disclaimer
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Author Details
Written By
Dr. Bhairavi S
Pharm. D
Reviewed By
Dr. Tejashwin Adiga
MBBS
Last updated : 10 Aug 2026 | 05:15 AM (IST)
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