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Biodronate 90mg Injection

Prescription Required

Salt Composition : Pamidronate

Manufacturer : UNITED BIOTECH PVT LTD

Origin of Medicine : India

MRP: 4640
Price :3843
You Save :797 (17%)

1 Vial(s)


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Introduction to Biodronate 90mg Injection

Biodronate 90mg Injection consists of the active substance Pamidronate. It is a medication that belongs to a class of drugs called bisphosphonates. It is used to treat high calcium levels in the blood, a condition known as hypercalcemia, which can be caused by cancer or other medical conditions. This helps to increase bone density and reduce the risk of fractures in people with osteoporosis (bone weakening) or other bone conditions. It works by slowing down the breakdown of bone tissue, which helps reduce the amount of calcium released into the bloodstream. The dosage and frequency of administration will depend on the individual's medical condition and other factors such as age, weight, and overall health.

Biodronate 90mg Injection can effectively treat bone disorders, but it may not be suitable for everyone. People with low calcium levels may need caution when taking this medication. Before starting treatment, discussing any potential risks and benefits with a healthcare provider is important. Like all medications, it can cause side effects. The most common side effects include fever, chills, fatigue, nausea, and vomiting. These side effects are usually mild and go away within a few days.  Patients receiving this medication should be closely monitored by their healthcare provider for potential side effects. Breastfeeding and pregnant women should also discuss their benefits and side effects with their healthcare provider before starting this medication.


Uses of Biodronate 90mg Injection

  • Hypercalcemia
  • Cancer-related bone diseases
  • Osteoporosis
  • Paget's disease of bone
  • Osteolytic Bone Metastases of Breast Cancer
  • Osteolytic lesions of Multiple Myeloma (a type of blood cancer)

Therapeutic Effects of Biodronate 90mg Injection

Biodronate 90mg Injection belongs to a class of drugs called bisphosphonates, which work by inhibiting the activity of cells called osteoclasts. Osteoclasts are responsible for breaking down bone tissue, which releases calcium into the bloodstream. By inhibiting osteoclasts' activity, it helps slow down the breakdown of bone tissue and reduce the amount of calcium released into the bloodstream.


Interaction of Biodronate 90mg Injection with other drugs

Inform your healthcare provider about all the medicines you take, including prescription medications, over-the-counter medications, nutritional or vitamin supplements, and herbal products. Certain medications may interact with Biodronate 90mg Injection and reduce effectiveness by causing undesirable side effects.


More Information about Biodronate 90mg Injection

  • Biodronate 90mg Injection is usually provided in the form of a powder for injection, and it should be stored in a cool, dry place at room temperature between 20°C and 25°C (68°F and 77°F).
  • It should be kept in its original packaging until it is ready to be prepared for use.
  • Once the powder is mixed with the appropriate sterile diluent, the resulting solution should be used immediately or within 24 hours if stored in the refrigerator between 2°C and 8°C (36°F and 46°F). Any unused solution should be discarded after this time and not be saved for later use.
  • If the medication needs to be transported, it should be kept in a cooler with ice packs to maintain the appropriate temperature.
  • Keep it out of reach from children and pets.

How to consume Biodronate 90mg Injection

Biodronate 90mg Injection is a medication that is administered by a healthcare professional, typically in a hospital or clinic setting. The medication is given as an intravenous (IV) injection by healthcare professional. The infusion typically takes several hours. You will be closely monitored during and after the infusion to ensure the medication works effectively and to watch for any side effects. The dosage and frequency of administration will depend on the condition being treated and your circumstances. Your healthcare provider will determine the appropriate dosage and schedule for you.


Safety Advices for Biodronate 90mg Injection

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Pregnancy

  

Biodronate 90 mg Injection is unsafe for a developing foetus and is not recommended for use during pregnancy unless necessary.

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Breast Feeding

  

It is unknown whether Biodronate 90mg Injection is excreted in human breast milk. Breastfeeding women should discuss the potential risks and benefits of the medication with their healthcare provider before starting treatment.

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Lungs

  

Biodronate 90mg Injection should be used cautiously in individuals with lung disease, as the medication can potentially worsen lung function. Your healthcare provider will monitor you closely if you have lung disease and adjust your dosage if necessary. If you have lung disease or a history of respiratory problems, discussing the potential risks and benefits of treatment with your healthcare provider is important. Your healthcare provider may recommend additional monitoring or testing to ensure the medication is not causing any adverse effects on your lungs.

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Liver

  

Biodronate 90mg Injection should be used cautiously in individuals with liver disease, as the medication is primarily metabolised in the liver and could potentially worsen liver function. Your healthcare provider will monitor you closely if you have liver disease and adjust your dosage if necessary.

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Alcohol

  

There are no known interactions between Biodronate 90mg Injection and alcohol. However, it is generally recommended to avoid consuming alcohol while being treated for a medical condition, as alcohol can potentially interfere with the effectiveness of the medication and increase the risk of side effects.

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Driving

  

Patients receiving Biodronate 90mg Injection should avoid driving or operating machinery if they experience side effects such as fatigue, dizziness, or blurred vision, impairing a patient's ability to drive or operate machinery safely.


Side Effects of Biodronate 90mg Injection

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.

Serious:

  • Kidney problems
  • Low calcium levels
  • Irregular heartbeat
  • Osteonecrosis of the jaw
  • Severe allergic reactions

Common:

  • Fever
  • Chills
  • Fatigue
  • Muscle aches
  • Nausea
  • Vomiting
  • Diarrhoea
  • Bone pain

Word of Advice

It is important to follow the healthcare provider's instructions carefully when receiving treatment with Biodronate 90mg Injection or any other medication. One of the most essential things you can do is attend all scheduled appointments. It will allow your healthcare provider to monitor your progress, check for any potential side effects, and adjust your treatment plan as needed. In addition to attending appointments, it is important to report any symptoms or side effects to your healthcare provider as soon as possible. It can help ensure that any issues are addressed promptly and effectively. Patients should avoid pregnancy while taking this drug. Maintaining a healthy lifestyle while receiving treatment is also essential. It includes eating a balanced diet, getting enough rest, and engaging in regular physical activity, as the healthcare provider recommends.Finally, being patient and staying positive throughout the treatment process is essential. Staying positive and optimistic can help you stay motivated and focused on your recovery.


FAQs

Q 1. Can Biodronate 90mg Injection Cause Jaw Problems?

Biodronate 90 mg Injection has been associated with a rare but serious side effect known as jaw osteonecrosis, which involves the death of bone tissue. This condition can cause pain, swelling, infection, and other complications.

Q 2. Can Biodronate 90mg Injection Cause Skin Reactions?

While skin reactions are not a common side effect of Biodronate 90mg Injection, some patients may experience rash, itching, or other skin irritation during or after treatment. Patients who experience severe or persistent skin reactions should contact their healthcare provider for further evaluation and treatment recommendations.

Q 3. Can Biodronate 90mg Injection be Given at Home?

Biodronate 90mg Injection infusions are typically administered in a healthcare setting, such as a hospital, clinic, or infusion center. However, some patients may be able to receive injection at home with appropriate monitoring and support from a healthcare provider.

Q 4. Can Biodronate 90mg Injection be Used in Children?

Biodronate 90mg Injection may be used in children in certain situations, such as in the treatment of osteogenesis imperfecta, a genetic condition that causes brittle bones. However, the safety and effectiveness in children have not been established for all conditions, so the decision in children should be made in consultation with a pediatric specialist.

Q 5. Is it safe to consume milk after being given an IV injection of Biodronate 90mg Injection?

It is generally recommended to wait at least 90 minutes after receiving an intravenous (IV) injection of Biodronate 90mg Injection before consuming any food or drink, including milk. This is to ensure that the medication has been fully absorbed into the body and to avoid any potential interactions with food or drink that may affect its absorption.

Q 6. Is My Daily Routine Life Hamper after Taking Biodronate 90 mg Injection?

Taking Biodronate 90mg Injection may not significantly affect your daily routine life, but it is important to follow your healthcare provider's instructions for post-treatment care. This may include avoiding activities that could cause injury or discomfort for some time after treatment, such as heavy lifting or strenuous exercise. Additionally, some people may experience side effects from the medication that could affect their daily routines, such as nausea or fatigue.

Q 7. What Food Is Good During the Treatment Period of Biodronate 90mg Injection?

When taking Biodronate 90mg Injection, it is important to maintain a healthy and balanced diet that includes foods high in calcium and vitamin D to support bone health. Some good food sources of calcium include dairy products such as milk, cheese, and yoghurt, as well as leafy green vegetables such as kale, spinach, and broccoli.


Fact Box of Biodronate 90mg Injection

Molecule name: Pemidronate

Therapeutic class: Bisphosphonates

Pharmacological class: Bisphosphonates

Indications: 

  1. Hypercalcemia.
  2. Cancer-related bone diseases
  3. Osteoporosis.
  4. Paget's disease of bone.
  5. Osteolytic Bone Metastases of Breast Cancer
  6. Osteolytic lesions of Multiple Myeloma 

References

  1. Hospira UK Ltd, U.S. Food and Drug Administration, Pamidronate Disodium. [24 Nov 2021], [Accessed on 31st March 2023] https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/020235s065lbl.pdf 
  2. Goodman and Gilman's,The Pharmacological Basis of Therapeutics,12th edition, 2018, 1688-1693
  3. Hospira UK Ltd, Electronic Medicines Compendium (EMC) [Revised on 30th March 2023] [Accessed on 1st Mar 2022], https://www.medicines.org.uk/emc/files/pil.6455.pdf

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